Series: Pharmacochemistry Library

Since its inception in 1977 the Pharmacochemistry Library has focussed mainly on developments in the field of Quantitative Structure-Activity Relationships (QSAR). However, although QSAR studies have contributed to a large extent to the results of modern medicinal chemistry research and are expected to continue to do so, they constitute only one aspect of current innovative research on bioactive compounds. Other techniques have emerged which have been found to be of great importance in this field. It was felt that these developments should be reflected in the Pharmacochemistry Library, the scope of which has therefore been enlarged to encompass the following topics:

• Innovative approaches, including topics such as improvements in QSAR methodologies, introduction of new techniques (e.g. specialised computer graphics) and application of existing techniques (e.g. X-ray) to medicinal chemistry

• (Q)SAR studies in specific fields and/or within certain classes of compounds

• Developments in new fields, e.g. the possibilities of certainly newly described physiological or pathological systems for developing new products

• Updating of medicinal chemistry in establishing fields, with special emphasis on the impact of recent findings or new techniques

• Molecular mechanisms involved in the wanted and unwanted effects of bioactive compounds and the exploitation thereof in drug design

• Drug design in general

• Proceedings of major symposia on medicinal chemistry

Book Series: Trends in Drug Research III

Most recent volume

Volume 32. Trends in Drug Research III

Published: 25th January 2002 Editor: H. van der Goot
The tradition of setting new trends in medicinal chemistry continued at the 13th Symposium where topics included chemical and biological diversity, new paradigms in drug action, and new insights in receptor mechanisms. Other topics of great interest discussed, and included in these proceedings, are the discoveries in green chemistry, the interface between organic synthesis and biosynthesis, the growing problem of resistant micro-organisms and the possibilities to identify new, and better, antibiotics. And finally, in recent developments, the discovery of small molecules with insulin sensitizing properties.

Additional volumes

Volume 31. Receptor Chemistry Towards the Third Millennium

Published: 31st May 2000 Editors: M. Gianella G. Marucci W. Quaglia U. Gulini

Volume 30. The Histamine H3 Receptor

Published: 9th December 1998 Editors: R. Leurs H. Timmerman

Volume 29. Trends in Drug Research II

Published: 1st January 1998 Editor: H. van der Goot

Volume 26. Stable Isotopes in Pharmaceutical Research

Published: 18th December 1997 Editor: T.R. Browne

Volume 28. XIVth International Symposium on Medicinal Chemistry

Published: 12th September 1997 Author: F. Awouters

Volume 25. Approaches to Design and Synthesis of Antiparasitic Drugs

Published: 10th July 1997 Editors: N. Anand S. Sharma†

Volume 27. Serotonin Receptors and their Ligands

Published: 10th July 1997 Editors: B. Olivier I. van Wijngaarden W. Soudijn

Volume 23. QSAR and Drug Design: New Developments and Applications

Published: 20th November 1995 Editor: T. Fujita Author: H. Timmerman

Volume 22. The Chemistry and Pharmacology of Taxol® and its Derivatives

Published: 16th June 1995 Editor: V. Farina Author: H. Timmerman

Volume 18. Trends in Receptor Research

Published: 17th August 1992 Editor: P. Angeli