Series: Comprehensive Analytical Chemistry

Comprehensive Analytical Chemistry presents the basic principles, recent developments and important applications of analytical chemistry. The volumes in this series discuss in depth topics regarding experimental phenomena, major advances, experimental approaches, essential instrumental methods, theoretical strategies and important applications within the field. The comprehensive coverage of this series also generates a broad appeal for graduate students and researchers in academia and industry. For more information about the series or to submit a proposal, please contact the Series Editor or the Acquisitions Editor, Susan Dennis at
Book Series: Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis

Most recent volume

Volume 71. Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis

Published: 1st June 2016 Series Volume Editors: Sandra Perez Peter Eichhorn Damia Barcelo

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance.

This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants.

This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications.

This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS.

Additional volumes

No Tech Hacking

Volume 66. Gold Nanoparticles in Analytical Chemistry

Published: 21st October 2014 Series Volume Editors: Miguel Valcárcel Ángela López-Lorente

Volume 59. Analysis and Risk of Nanomaterials in Environmental and Food Samples

Published: 31st August 2012 Editors: Damia Barcelo Marinella Farré

Volume 72. Rapid Immunotests for Clinical, Food and Environmental Applications

Published: 1st July 2016 Series Volume Editor: Irina Goryacheva

Volume 48. Passive Sampling Techniques in Environmental Monitoring

Published: 10th May 2007 Editors: Richard Greenwood Graham Mills Bran Vrana

Volume 57. Green Analytical Chemistry

Published: 27th October 2010 Authors: Miguel de la Guardia Sergio Armenta

Volume 69. Chemical Imaging Analysis

Published: 8th June 2015 Authors: Freddy Adams Carlo Barbante

The Immunoassay Handbook

Volume 31. Surfactants in Analytical Chemistry

Published: 9th August 1996 Authors: E. Pramauro E. Pelizzetti

Ninja Hacking

Volume 60. Food Protected Designation of Origin

Published: 1st July 2013 Series Volume Editors: Miguel de la Guardia Ana Gonzalvez Illueca

Volume 68. Advanced Mass Spectrometry for Food Safety and Quality

Published: 8th May 2015 Series Volume Editor: Yolanda Picó

Volume 63. Fundamentals of Advanced Omics Technologies: From Genes to Metabolites

Published: 15th November 2008 Series Volume Editors: Carolina Simó Alejandro Cifuentes Virginia García-Cañas

Volume 67. Persistent Organic Pollutants (POPs): Analytical Techniques, Environmental Fate and Biological Effects

Published: 3rd March 2015 Series Volume Editor: Eddy Zeng

Volume 65. Analysis of Marine Samples in Search of Bioactive Compounds

Published: 29th August 2014 Series Volume Editors: Teresa Rocha-Santos Armando Duarte

Volume 56. Hypercrosslinked Polymeric Networks and Adsorbing Materials

Published: 6th October 2010 Authors: Vadim Davankov Maria Tsyurupa

Volume 47. Modern Instrumental Analysis

Published: 17th October 2006 Editors: Satinder Ahuja Neil Jespersen

Volume 53. Molecular Characterization and Analysis of Polymers

Published: 24th October 2008 Editors: John Chalmers Robert Meier

Volume 15. Methods of Organic Analysis

Published: 1st June 1983 Editor: G. Svehla Author: L. Mázor

Volume 14. Ion Exchangers in Analytical Chemistry

Published: 1st September 1982 Editor: G. Svehla Author: M. Marhol

Volume 64. Applications of Advanced Omics Technologies: From Genes to Metabolites

Published: 4th June 2014 Series Volume Editors: Virginia García-Cañas Alejandro Cifuentes Carolina Simó

Volume 61. Advanced Techniques in Gas Chromatography-Mass Spectrometry (GC-MS-MS and GC-TOF-MS) for Environmental Chemistry

Published: 23rd October 2013 Series Volume Editors: Imma Ferrer E. Thurman

Volume 9. Ultraviolet Photoelectron and Photoion Spectroscopy, Auger Electron Spectroscopy, Plasma Excitation in Spectrochemical Analysis

Published: 1st January 1979 Editor: G. Svehla

Volume 10. Organic Spot Test Analysis: The History of Analytical Chemistry

Published: 1st January 1980 Editor: G. Svehla

Volume 45. Analysis and Detection by Capillary Electrophoresis

Published: 6th September 2005 Editors: Maria Luisa Marina Angel Ríos Miguel Valcárcel

Volume 62. Analysis, Removal, Effects and Risk of Pharmaceuticals in the Water Cycle

Published: 3rd September 2007 Series Volume Editor: Sandra Perez

Volume 32. Environmental Analytical Chemistry

Published: 13th April 1999 Authors: D. Pérez-Bendito S. Rubio

Volume 43. Chromatographic-Mass Spectrometric Food Analysis for Trace Determination of Pesticide Residues

Published: 11th December 2004 Author: A.R. Fernandez Alba

Volume 42. Non-destructive Micro Analysis of Cultural Heritage Materials

Published: 26th November 2004 Editors: K. Janssens R. Van Grieken

Volume 41. Sample Preparation for Trace Element Analysis

Published: 16th December 2003 Authors: Zoltan Mester Ralph Sturgeon

Volume 38. Countercurrent Chromatography

Published: 10th October 2002 Author: A. Berthod

Volume 44. Biosensors and Modern Biospecific Analytical Techniques

Published: 2nd April 2005 Editor: L. Gorton

Volume 49. Electrochemical Sensor Analysis

Published: 5th September 2007 Editors: Salvador Alegret Arben Merkoci

Volume 55. Comprehensive two dimensional gas chromatography

Published: 22nd July 2009 Editor: Lourdes Ramos

Volume 37. Sampling and Sample Preparation in Field and Laboratory

Author: Janusz Pawliszyn

Volume 54. Advances in Flow Injection Analysis and Related Techniques

Published: 15th November 2008 Series Volume Editors: Spas Kolev Ian McKelvie

Volume 35. Modern Fourier Transform Infrared Spectroscopy

Published: 26th October 2001 Authors: A.A. Christy Y. Ozaki V.G. Gregoriou

Volume 51. Food Contaminants and Residue Analysis

Published: 28th July 2008 Author: Yolanda Picó

Volume 29. Chemiluminescence Immunoassay

Published: 4th December 1991 Author: I. Weeks

Volume 52. Protein Mass Spectrometry

Published: 2nd September 2008 Editor: Julian Whitelegge

Volume 58. TOF-MS within Food and Environmental Analysis

Published: 2nd August 2012 Editor: Amadeo Rodriguez Fernandez-Alba

Volume 33. Elemental Speciation

Published: 12th December 2000 Authors: J.A. Caruso K.L. Sutton K.L. Ackley

Volume 37. Sampling and Sample Preparation in Field and Laboratory

Published: 9th September 2002 Author: Janusz Pawliszyn

Volume 27. Analytical Voltammetry

Published: 17th January 1992 Editors: M.R. Smyth J.G. Vos

Volume 40. Analysis and Fate of Surfactants in the Aquatic Environment

Published: 22nd August 2003 Authors: Thomas Knepper Pim de Voogt Damia Barcelo

Volume 36. Chemical Test Methods of Analysis

Published: 15th March 2002 Editors: Zolotov Ivanov Amelin

Volume 34. Discrete Sample Introduction Techniques for Inductively Coupled Plasma Mass Spectrometry

Published: 12th December 2000 Authors: D. Beauchemin D.C. Grégoire D. Günther V. Karanassios Jean-Michel Mermet T.J. Wood

Volume 30. Spectrochemical Trace Analysis for Metals and Metalloids

Published: 9th May 1996 Authors: R. Lobinski Z. Marczenko

Volume 39. Integrated Analytical Systems

Published: 19th June 2003 Author: Salvador Alegret

Volume 46. Proteomics & Peptidomics

Published: 16th December 2005 Editor: Gyorgy Marko-Varga

Volume 28. Analysis of Substances in the Gaseous Phase

Published: 6th November 1991 Authors: E. Smolkova-Keulemansova L. Feltl