Antibody-drug conjugates: Converting our expanding knowledge of disease and immune system biology into successful immunotherapeutics
Antibody-drug conjugates, or ADCs, are a class of exciting new therapeutics that utilize the patient’s own immune system, with the antibody delivering the drug right to the disease site
There are two ADCs currently being used to treat lymphoma and breast cancer in patients, with dozens more in clinical development. Yet challenges remain, and new tools and methods must be designed to deal with them.
This white paper discusses:
- Early clinical failures of ADCs and what was learned from those failures
- Selecting the tumor antigen target in ADC development
- How monoclonal antibodies serve as vehicles to deliver a drug to the disease site
Read the white paper.
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