University of Oxford, UK
Talk Title: Preclinical and clinical development of ChAdOx1 nCoV-19
Dr. Gilbert completed her undergraduate studies at the University of East Anglia and her doctoral degree at the University of Hull. Following four years as a research scientist at the biopharmaceutical company Delta Biotechnology she joined the Nuffield Department of Medicine (NDM) at Oxford University in 1994 and became part of the Jenner Institute (within NDM) when it was founded in 2005.
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Her chief research interest is the development of viral-vectored vaccines that work by inducing strong and protective T and B cell responses. She leads the Jenner Institute programme in influenza vaccine development and also works on vaccines for many different emerging pathogens, including Nipah, MERS, Lassa, Crimean-Congo haemorrhagic fever, and SARS-CoV-2. Working with colleagues in the Jenner Institute research labs, the Clinical Biomanufacturing Facility and Centre for Clinical Vaccinology and Tropical Medicine, all situated on the Old Road Campus in Oxford, she is able to take novel vaccines from design to clinical development, with a particular interest in the rapid transfer of vaccines into manufacturing and first in human trials. She is the Oxford Project Leader for ChAdOx1 nCoV-19, a promising vaccine against the novel coronavirus, SARS-CoV-2.
Barney Graham, NIAID Vaccine Research Center, USA
London School of Hygiene & Tropical Medicine, UK
Heidi J. Larson, PhD, is Professor of Anthropology, Risk and Decision Science and Director of the Vaccine Confidence Project at the London School of Hygiene & Tropical Medicine. She is also Clinical Professor and Director of European Initiatives at the Institute of Health Metrics and Evaluation, University of Washington, Seattle, USA, and Associate Professor, Centre for Evaluation of Vaccination, University of Antwerp, Belgium.
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Prof. Larson’s research focuses on the analysis of social and political factors that can affect uptake of health interventions. She previously headed UNICEF’s global communication work around new vaccine introduction and chaired the GAVI Advocacy Task Force. She served on the FDA Medical Countermeasure (MCM) Emergency Communication Expert Working Group and is Principle Investigator of the EU-funded (EBODAC) project on the deployment, acceptance and compliance of an Ebola vaccine trials in Africa.
The Vaccine Confidence Project has developed multiple metrics to measure population confidence in vaccines, from a survey-based Vaccine Confidence Index™ to monitoring media and social media, qualitative research to understand the drivers of vaccine reluctance and refusal, and tracking the ecology of rumours and transnational influences on public trust in vaccines. Prof. Larson is also author of Stuck: How Vaccine Rumors Start ― and Why They Don't Go Away. (Oxford U Press, 2020)