Industry Insights - Pharma & Life Sciences


    Added 20th June 2016
    With an astonishing one million new articles being published every year, the wealth of knowledge now available to researchers is beginning to look more like a burden than a blessing. ...

    Added 31st May 2016
    For the successful discovery and eventual launch of drugs, researchers need to use all of the available information. However, traditional literature searches of full-text articles are laborious and limiting research ...

    Added 31st May 2016
    Too many drugs still cause adverse events after reaching clinical trials, despite all the efforts to eliminate unsafe candidates early. This late-stage attrition remains one of the greatest—and most costly—challenges ...

    Added 31st May 2016
    Finding disease-specific drug targets is becoming more straightforward thanks to the development of text-mining technology. The advances in informatics that allow researchers to search vast virtual libraries have made it ...

    Added 31st May 2016
    The role of in silico profiling in the drug candidate selection process is growing. Clinical outcome predictions are proving increasingly accurate thanks to both the available higher-quality data and the ...

    Added 31st May 2016
    Understanding diseases at a molecular level is essential to the accurate identification of drug targets and the discovery of successful drug candidates. To predict a drug’s impact, researchers must have ...

    Added 30th May 2016
    Addressing unanticipated problems with a drug candidate can be very expensive, especially if the candidate reaches clinical trials before the problem is discovered. The solution is to identify all potential ...

    Added 10th March 2016
    Life sciences companies are spending more on R&D but are earning less for their efforts. However, dealing with more data does not have to mean reduced productivity. Discover why companies ...

    Added 19th January 2016
    This white paper looks at how small steps, such as greater data sharing and extending data searches beyond standard literature searches, can bring about huge improvements to pre-clinical R&D productivity. ...

    Added 22nd December 2015
    QSAR modeling is a powerful tool in the assessment of new chemical entities. Using the example of ErB1 kinase, the dysfunction of which has been implicated in diseases such as ...

    Added 17th December 2015
    In silico studies at the interface of biology and chemistry can help medicinal chemists and pharmacologists identify innovative leads, optimize selectivity issues and select appropriate test conditions. This new application ...

    Added 30th October 2015
    Despite the promise of T-type calcium channels as a drug target, the first marketed blocker was withdrawn due to adverse drug interactions. Can virtual screening of potential ligands help identify ...

    Added 30th October 2015
    Most traditional drugs act on more than one target, meaning their pharmacological profile is quite complex. Comparing the compound–target affinities of chemical substances can reveal considerable information for drug repurposing ...

    Added 14th October 2015
    The European Medicines Agency (EMA) recently launched their new literature-screening service, Medical Literature Monitoring (MLM). Whether it will ultimately lessen the burden on market authorization holders or add unwanted complexity ...

    Added 13th October 2015
    New targeted medications have revealed the value of matching patient and therapy, but the narrow indications for such drugs call for big changes in the way drugs are developed.Discover more ...

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