Preclinical safety programs often follow a standard template to determine off-target effects. ...

With the growing number of high-profile safety-related drug withdrawals and the increasing consumer expectations of drug safety. ...

The scope of what pharmacovigilance leaders must consider has greatly increased as regulatory agencies worldwide have broadened their expectations. ...

Practical steps that pharmacovigilance leaders should take in order to achieve and maintain global oversight of their pharmacovigilance process. ...

Technological advances in the retrieval and assessment of data have enabled a straightforward and elegant means to create predictive models of compound. ...

There is no room for error when it comes to pharmacovigilance. The FDA and EMA expect 100% of adverse drug reactions to be found in the literature ...

Precision medicines display high efficacies against their target groups, but they still face the same problems as other drugs: high attrition rates ...

Since the early 1990s, R&D expenditure by U.S. pharmaceutical companies has grown exponentially, but not because more drugs are being produced and approved ...

Antibody-drug conjugates, or ADCs, are a class of exciting new therapeutics that utilize the patient’s own immune system, with the antibody ...

The vision for precision medicine is that it will offer improved treatments for patients, while also optimizing the drug development process as a whole. ...

Partnering with outside organizations, such as small biotech firms, academic institutions, CROs and individual experts, has become vital for the health ...

By boosting anti-cancer response using a patient’s own immune system, immunotherapeutics are showing incredible promise ...

Precision medicine has significantly progressed in the last several years as it has become possible to find more tailored treatments for patients ...

A combination of high-quality, accessible data and powerful in silico profiling solutions has proven to accurately predict the potential of lead compounds. ...

Understanding complex biological processes is critical whether doing basic research or trying to find the next blockbuster drug. ...