Infants’ Regulatory Behaviors and Maternal Mental Health May Predict Unexplained Physical Symptoms in Older Children
Cincinnati, OH, September 27, 2012 – Functional somatic symptoms (FSS) are physical complaints, such as headaches, pain, fatigue, and dizziness, that cannot be explained medically. These symptoms affect 10-30% of children and adolescents and account for 2-4% of all pediatric doctor visits. A new study scheduled for publication in The Journal of Pediatrics finds that infants with regulatory problems (i.e., feeding, sleeping, and tactile reactivity) and/or maternal psychiatric problems may have an increased risk of FSS in later childhood.
It is believed that maternal anxiety and depression can influence the child’s capacity to self-regulate, but infant problems can also exaggerate parental problems. Charlotte Ulrikka Rask, MD, PhD, Child and Adolescent Psychiatrist at Aarhus University Hospital in Denmark, states, “Parents of infants with regulatory problems could be taught to help their infants regulate their behavioral and physiological state, which potentially could reduce the risk of later development of impairing FSS.”
Dr. Rask and colleagues from Aarhus University Hospital and Copenhagen University Hospital in Denmark prospectively assessed 1,327 5-7-year-old children who are part of the Copenhagen Child Cohort (6,090 children born around Copenhagen in 2000). Home health nurses assessed infants 4 times before they were 10 months of age. Maternal mental health was assessed by self-report 1-5 weeks after child birth, and researchers checked whether mothers had been diagnosed with a mental disorder during the infant’s first year of life. Three overall factors were assessed: (1) infant regulatory factor; (2) maternal postnatal psychiatric illness; and (3) annual household income.
At 5-7 years of age, 23.2% of the children had FSS, with an increased prevalence in girls (27.6% versus 18.8%). Impairing, or severe, FSS was seen in 4.4% of the children. Limb pain, headaches, and stomach aches were the most frequent FSS reported. Thirteen mothers were diagnosed with depression, bipolar disorder, or anxiety during their infants’ first year of life; the infants of these mothers were 7 times more likely to develop FSS at 5-7 years of age. Infants with 2 or more regulating issues had a nearly 3-fold increased risk of FSS at 5-7 years of age. There was no association between impairing FSS and household income early in life.
Because recent studies have suggested that eating and sleeping problems during early childhood may be risk factors for mood and anxiety disorders and FSS (e.g., recurrent abdominal pain) later in life, early intervention is important for both parents and infants. Dr. Rask suggests, “Interventions should include strategies to improve maternal mental health and parents’ ability to handle the infant’s regulatory problems, as well as strategies that focus on infants who have multiple regulatory problems.”
# # #
Notes for editors
“Infant Behaviors are Predictive of Functional Somatic Symptoms at the Age of 5-7 Years: Results from the Copenhagen Child Cohort CC2000,” by Charlotte Ulrikka Rask, MD, PhD, Eva Ørnbøl, MSc, Else Marie Olsen, MD, PhD, Per Fink, MD, DmSci, and Anne Mette Skovgaard, MD, DmSci, appears in The Journal of Pediatrics(www.jpeds.com), DOI 10.1016/j.jpeds.2012.08.001.
About The Journal of Pediatrics
The Journal of Pediatrics is a primary reference for the science and practice of pediatrics and its subspecialties. This authoritative resource of original, peer-reviewed articles oriented toward clinical practice helps physicians stay abreast of the latest and ever-changing developments in pediatric medicine. The Journal of Pediatrics is ranked 4th out of 113 pediatric medical journals (2011 Journal Citation Reports®, published by Thomson Reuters). URL: www.jpeds.com
Elsevier is a world-leading provider of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders. Elsevier’s online solutions include ScienceDirect, Scopus, Reaxys, ClinicalKey and Mosby’s Nursing Suite, which enhance the productivity of science and health professionals, and the SciVal suite and MEDai’s Pinpoint Review, which help research and health care institutions deliver better outcomes more cost-effectively.
A global business headquartered in Amsterdam, Elsevier employs 7,000 people worldwide. The company is part of Reed Elsevier Group PLC, a world-leading publisher and information provider, which is jointly owned by Reed Elsevier PLC and Reed Elsevier NV. The ticker symbols are REN (Euronext Amsterdam), REL (London Stock Exchange), RUK and ENL (New York Stock Exchange).
Elsevier is a global information analytics business that helps institutions and professionals advance healthcare, open science and improve performance for the benefit of humanity. Elsevier provides digital solutions and tools in the areas of strategic research management, R&D performance, clinical decision support and professional education, including ScienceDirect, Scopus, SciVal, ClinicalKey and Sherpath. Elsevier publishes over 2,500 digitized journals, including The Lancet and Cell, more than 38,000 e-book titles and many iconic reference works, including Gray's Anatomy. Elsevier is part of RELX Group, a global provider of information and analytics for professionals and business customers across industries. www.elsevier.com
+1 513 636 7140