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Reaxys is an innovative chemistry database that optimizes small molecule discovery
Discover, innovate and develop with confidence. Reaxys combines a billion chemistry data points from chemical patents and literature with analytical and predictive tools. Go further, faster with Reaxys.
Trusted data, technology and expertise to support chemistry research
Gain critical insights to inform decision making and transform workflows
An unparalleled breadth of chemistry data, literature and flexible technology help you:
Mitigate IP risk with the largest collection of patents in a chemistry database
Stay abreast of developments in pharma and chemical research, and identify innovation opportunities
Break down information silos by integrating in-house and external data
Power custom chemistry applications, including AI models
Design new substances and optimize their properties
Use the largest and most reliable collection of physicochemical, toxicology and bioactivity data to:
Design novel compounds with improved properties, from target affinity to conductivity or solubility
Anticipate safety risks and assess the toxicology and ADME profile of compounds
Optimize potency and selectivity of leads with SAR
Generate high-quality synthesis routes in minutes
Discover a tool combining high-quality reaction data with AI technology to:
Access scientifically robust predicted and published routes in minutes
Analyze and edit reaction steps by reviewing underlying literature references and experimental conditions, all in one view
Select routes to take to the lab based on commercial availability of starting materials
Connected, configurable solutions to innovate in R&D
Advance your R&D with Elsevier’s Reaxys and a portfolio of solutions for pharmaceutical and chemicals and materials R&D. Strengthen confidence in your business decisions, supported by:
Trusted quality information from peer-reviewed scientific literature to regulatory data
Innovative technology that powers data transformation and analytical and predictive tools
Domain and data science expertise to solve complex problems with data solutions for R&D
Information integrity is essential to your progress. Discover trusted data and tools that deliver critical insights. Let's shape progress together.
The trusted quality data and innovative technology that deliver chemistry insights
113 million documents, 43 million patents
Comprehensive and up-to-date journal and patent coverage from 18,000 journals and 105 patent offices.
283 million substances, 500 million physicochemical data points
Substances from articles, patents and commercial catalogs, including experimental data (NMR, Mass, IR spectra, crystal properties, solubility, etc.)
46 million bioactivities
Normalized bioactivity data points with references (in-vivo and in-vitro toxicity, ADME). SAR analysis with heat map.
Predictive retrosynthesis
Combination of AI technology and 73 million high-quality reactions, including references and experimental procedures.
338 million commercial products
Up-to-date commercial availability of 110 million substances (with price, purity and package size) from 520 suppliers. Option to define preferred vendors.
Comprehensive, trusted, machine-readable chemistry data
Curated chemical data via API and secure data download for search, discovery and predictive modeling applications.
"Reaxys provides our researchers with rich data and comprehensive perspectives for problem solving, and thus ensures that our synthetic work is based on better solutions."
RM
Rujian Ma
Vice President of Chemistry at WuXi AppTec
Frequently asked questions
Chemical searches in Reaxys are different due to:
Options for searching structures, reactions, keywords and property values
The unique ability to combine structure and text searches
A transparent query process with an easy-to-follow path to results
You can integrate in-house and external data in a proprietary version of Reaxys. Critical in-house knowledge becomes searchable and actionable. This seamless integration sets Reaxys apart from other chemistry research solutions.
Reaxys includes:
Organic, inorganic and organometallic substances
Chemical reactions
Published experimental facts, including substance property, spectral and reaction data
Chemical patents
Yes, Reaxys has the largest collection of new pharma and chemical patents from 105 patent offices. Titles, abstracts and claims are translated to English. Fastest access to substances in newly published patents — only five days after publication