Building a one-stop platform for chemistry information

Lundbeck, a global pharmaceutical company that specializes in diseases of the brain, is collaborating with Elsevier on an ambitious project. They’re planning to integrate their internal data with content from Reaxys and Reaxys Medicinal Chemistry in a one-stop platform for chemistry and pharmacology information. Dr. Ludovic Tranholm Otterbein, Director of the Research Informatics & Operations Department at Lundbeck, met with Elsevier to discuss the project.

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Lundbeck, a global pharmaceutical company that specializes in diseases of the brain, is collaborating with Elsevier on an ambitious project.

Challenge

Collaboration with multiple global organizations leads to challenges in managing a company knowledge base. Lundbeck receives data from multiple internal labs and external contractors, each of which used their own system for recording information, leading to low data interoperability. This made it more difficult to discover, compare and use data points. Added to this was the challenge of integrating internal and external data with content from commercial databases.

Ideally, all those engaged in pharmaceutical development should be able to access all the relevant data through one cheminformatics platform. According to Dr. Otterbein, “The potential to improve productivity with a one-stop platform for chemical and bioactivity data was undeniable.”

“When we looked at Reaxys, the potential to integrate its content with our data was very attractive.” Dr. Ludovic Tranholm Otterbein,
Director of Research Informatics & Operations, Lundbeck

Solution

Lundbeck trialled Reaxys and Reaxys Medicinal Chemistry, comparing the two Elsevier solutions with another tool they had been using to access external content. When they were satisfied with the value of the Reaxys content, they kicked off the project to integrate it with their own data. The project is ongoing. Having created the platform and its connections to their own data, data from CROs and data from Reaxys, they are now looking at other integrations and possibilities.

Impact

Dr. Otterbein is very satisfied with the results of the collaboration, describing the support from Elsevier’s Professional Services team as great and his scientists as happy. “We’ve provided a platform for all our scientists to access our internal and external data. And it was relatively fast: in a few months, we were able to break apart the data silos at Lundbeck and create the integration with our ELNs. And we’re impressed with the flexibility and customer focus that Elsevier has shown.”

“To the best of my knowledge, Reaxys is the only chemistry-centric database that enables users to access reactions, informational substances, and documents covering the in vitro and in vivo spaces.”
Dr. Ludovic Tranholm Otterbein,
Director of Research Informatics & Operations, Lundbeck