Interview with Dr. Takahashi Nakai at Ironwood

Reaxys enables users engaged in pharmaceutical R&D to look at data from a biological point of view

According to Dr. Takahashi Nakai of Ironwood Pharmaceuticals, Reaxys provides unique services in the form of extracted property and reaction data, possibilities to look at chemical information from a biological point of view, and links to eMolecules with purchase information. See how that benefits his workflow in this interview.

Interview with Dr. Takahashi Nakai at Ironwood

Challenge

Working at the interface of pharmacology and chemistry, Ironwood Pharmaceuticals has a high demand for credible, accurate and current chemical information. Researchers like Takahashi Nakai have to develop synthetic routes for compounds that will affect proposed targets and successfully predict the behavior of those compounds in vivo. This means needing to search for both chemical and bioactivity data.

Solution

Dr. Nakai relies on Reaxys, which he says is tailored for his needs as a chemist. He routinely uses it to search for structures, specific targets, patents and other literature. He is particularly pleased that he can filter hits using biological parameters, which makes his work on compound pharmacology much easier. In addition, when he has found an optimal synthesis route for the lead compound, he can look for ordering information thanks to the web link to eMolecules.


Interview with Dr. Takahashi Nakai, Ironwood Pharmaceuticals - Reaxys

Reaxys helps us in our endeavor to avoid the mistakes made by others. Dr. Takahashi Nakai, Associate Research Scientist at Ironwood Pharmaceuticals


Impact

Dr. Meulemans says that Reaxys is extremely easy to use, even for beginners, and always gives the data they need. It's the most suitable product in terms of content and functionality, particularly how the data are organized and how results are presented. In just two weeks, they were able to scale production of a compound from miligrams to hundreds of grams, thanks to information from Reaxys.

I think Reaxys saves us a significant amount of time because we don’t have to wait for information to arrive. Dr. Takahashi Nakai, Associate Research Scientist at Ironwood Pharmaceuticals


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