Skip to main content

Unfortunately we don't fully support your browser. If you have the option to, please upgrade to a newer version or use Mozilla Firefox, Microsoft Edge, Google Chrome, or Safari 14 or newer. If you are unable to, and need support, please send us your feedback.

Publish with us
Periosteal Nerve
Skeletal System

Periosteal Nerve

Nervus periostei

Read more

Quick Facts

Periosteal nerves are nociceptive and transmit pain signals to the central nervous system.

Complete Anatomy
The world's most advanced 3D anatomy platform
Try it for Free


The periosteal nerves are a network of nerves located between the two layers of the periosteum, the fibrous layer and the osteogenic layer.

Anatomical Relations

In cortical bone, the periosteal nerves follow a similar path to the periosteal blood vessels. They form plexuses between the layers of the periosteum before branching into the underlying compact bone below via perforating canals.


Periosteal nerves are mainly sensory nerves that transmit pain signals. Due to the presence of sensory receptors, the fibrous layer of periosteum is the most pain-sensitive area of bone, which can be caused by a number of factors including trauma and osteoarthritis (Standring, 2016).


Standring, S. (2016) Gray's Anatomy: The Anatomical Basis of Clinical Practice. Gray's Anatomy Series: Elsevier Limited.

Complete Anatomy

The world's most advanced 3D anatomy platform

Complete Anatomy