Quick Facts
The substantia nigra is located in the midbrain and plays an important role in reward, addiction and movement. The substantia nigra appears darker than neighboring areas, due to high levels of melanin in dopaminergic neurons. Parkinson's disease is characterized by the death of dopaminergic neurons in the substantia nigra.
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Substantia nigra
Parkinson's disease is a dyskinesia disease caused by the progressive degeneration and reduction of dopamine neurons in substantia nigra.
