Improving productivity in early drug discovery
Reaxys Medicinal Chemistry facilitates rapid discovery of bioactivity data, including structure–activity relationships. Using the same user-friendly interface as Reaxys, it is designed to boost early drug development.
See how Reaxys Medicinal Chemistry can benefit your organization.
Get a biological perspective on chemistry data to empower drug discovery workflows
Making informed decisions in early drug discovery requires data on the bioactive and drug-like properties of substances, especially about their affinity for protein targets in vivo. However, getting this biological perspective on chemical data is difficult with many chemistry research solutions due to the lack of comparability of data from different sources.
Reaxys Medicinal Chemistry, which is available as a standalone research solution or as a fully integrated solution with Reaxys, offers dedicated indexing and query forms to ensure that users can quickly and easily find pharmacological information about chemical substances. What’s more, regardless of source, the data are normalized and offered in a standardized form to ensure comparability.
Perform quick MedChem searches
Quick Search accepts bioactivity-focused queries using keywords like
targets of [drug name],
QSAR of [drug name] and
bioactivity of [drug name].
Use dedicated MedChem search forms
Query Builder includes 19 query forms that offer easy-to-understand predefined parameter fields so even beginners can build complex searches and tap into the incredible wealth of available medicinal chemistry data. Simply expand the MedChem menu in the right-hand column of Query Builder to access these forms.
Continue your search with Heatmap
The Heatmap is available to all users with a Reaxys Medicinal Chemistry license. It facilitates comparisons of biodata from different publications using pX values (normalized affinity values assigned to the data). Heatmap appears with a simple click on the icon in the top right of every relevant substance, reaction and document screen and helps users continue their medicinal chemistry investigations.
Discover some powerful applications of Reaxys Medicinal Chemistry
- Ensuring the pharmacological and safety profile of new antipsychotics
- Analyzing in vitro results for 5-HT Ligands
- Re-examining the potential of barbiturates
- Assessing the polypharmacology of 1,4 - benzodiazepines
- In silico investigation of off-target effects
- QSAR modeling of ErbB1 inhibitors using genetic algorithm-based regression