Skip to main content

Unfortunately we don't fully support your browser. If you have the option to, please upgrade to a newer version or use Mozilla Firefox, Microsoft Edge, Google Chrome, or Safari 14 or newer. If you are unable to, and need support, please send us your feedback.

Publish with us
Transverse Colon


Tela submucosa

Read more

Quick Facts

The submucosa is the layer of loose connective tissue between the tunica mucosa and the tunica muscularis in most parts of the digestive, respiratory, urinary, and genital tracts (Dorland, 2011).

Complete Anatomy
The world's most advanced 3D anatomy platform
Try it for Free


The submucosa is composed of a series of layers of irregular dense connective tissue with each layer measuring 0.5-2.0 μm in thickness. There are blood vessels, nerves, and lymphatics within these layers. It has raised, jagged projections which form the core of the inner circular folds.

Anatomical Relations

The submucosa is found between the muscularis mucosa and the circular muscular layer.


The submucosa has a variety of functions, which are based on the orientation of its collagenous and elastin fibers. They contribute to the overall structural support and strength, as well as its elasticity. This array of fibers also facilitates the action of peristalsis by enabling movement changes in the transverse and longitudinal dimensions; resulting in a wavelike contraction (Standring, 2016; Pocock, Richards and Richards, 2013).


Dorland, W. (2011) Dorland's Illustrated Medical Dictionary. 32nd edn. Philadelphia, USA: Elsevier Saunders.

Pocock, G., Richards, C. D. and Richards, D. A. (2013) Human Physiology. Oxford Core Texts 4 edn.: OUP Oxford.

Standring, S. (2016) Gray's Anatomy: The Anatomical Basis of Clinical Practice. Gray's Anatomy Series 41st edition edn.: Elsevier Limited.

Complete Anatomy

The world's most advanced 3D anatomy platform

Complete Anatomy