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Lamina Propria

Lamina Propria

Lamina propria

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Quick Facts

The lamina propria is the connective tissue coat of a mucous membrane just deep to the epithelium and basement membrane (Dorland, 2011).

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Structure and/or Key Features

The lamina propria is a loose connective areolar tissue layer forming a deeper part of the mucosal layer of the oral mucosa. It serves as a protective barrier, as well as providing immune cells when needed.


The lamina propria houses a rich supply of immune cells in response to the desquamation of superficial epithelial apoptotic or necrotic cells. It also serves a mechanical protective function by its service as a barrier, preventing internal tissue access of external pathogens and microorganisms.


Dorland, W. (2011) Dorland's Illustrated Medical Dictionary. 32nd edn. Philadelphia, USA: Elsevier Saunders.

Anatomical Relations

The lamina propria is situated deep to the basement membrane of the olfactory epithelium, separating it from the cribriform plate of the ethmoid bone.

Clinical Correlates


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