Skip to main content

Unfortunately we don't fully support your browser. If you have the option to, please upgrade to a newer version or use Mozilla Firefox, Microsoft Edge, Google Chrome, or Safari 14 or newer. If you are unable to, and need support, please send us your feedback.

Publish with us
Serosa of Gallbladder
Digestive System

Serosa of Gallbladder

Tunica serosa vesicae biliaris

Read more


The serosa is the outer membrane covering the gallbladder. It consists of an external layer of secretory epithelium and a deep layer of connective tissue applied to the external surface of the gallbladder (perimuscular fibrous layer). It covers most of the fundus, inferior surface, and sides. The serosa normally does not extend onto the surface of the gallbladder that is adherent to the liver.

Complete Anatomy
The world's most advanced 3D anatomy platform
Try it for Free

Key Features/Anatomical Relations

The serosa of the gallbladder is the part of the visceral peritoneum. The gallbladder is attached to the inferior surface of the right lobe of the liver by the serous coat. The anterior-most portion of the gallbladder, the fundus, usually projects beyond the anterior border of the liver. It can extend far enough to contact the anterior abdominal wall; in which case the parietal peritoneum of the anterior abdominal wall and the visceral peritoneum of the gallbladder minimize contact friction.


The serosa of the gallbladder secretes serous fluid into the peritoneal space, and it lubricates movement of abdominal contents, in this case the gallbladder, as they rub against each other.

Learn more about this topic from other Elsevier products


ScienceDirect image

The serosa is a single outer cell layer of tissue made of epithelial cells that envelop the uterus.

Explore on ScienceDirect(opens in new tab/window)

Complete Anatomy

The world's most advanced 3D anatomy platform

Complete Anatomy