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Press release

Featured articles from the journal CHEST®, December 2022

Glenview, Illnois | December 15, 2022

Published monthly, the journal CHESTopens in new tab/window® features peer-reviewed, cutting-edge original research in chest medicine: Pulmonary, critical care and sleep medicine and related disciplines. Journal topics include asthma, chest infections, COPD, critical care, diffuse lung disease, education and clinical practice, pulmonary vascular disease, sleep, thoracic oncology and the humanities.

The December issueopens in new tab/window of CHEST contains 36 articles, including clinically relevant research, reviews, case series, commentary and more. Each month, the journal also offers complementary web and multimedia activitiesopens in new tab/window, including visual abstracts, to expand the reach of its most interesting, timely and relevant research.

“Well-suited for the final issue of 2022, the December issue of the journal CHEST includes articles that look back at lessons learned from the COVID-19 pandemic and insights into planning for future surges,” says Editor-in-Chief of the journal CHEST, Peter Mazzone, MD, MPH, FCCP. “’COVID-19: Lessons Learned, Lessons Unlearned, Lessons for the Futureopens in new tab/window’ was written by editorial board members for the critical care section of the journal CHEST and ‘A Regional Command Center for Pandemic Surgeopens in new tab/window’ is a prospective observational study conducted in Catalonia from March 15, 2020, to July 1, 2021.”

Also included in the current issue of the journal CHEST:

  • Chest Infections

Recommending constant microbiological surveillance, “Multidrug-Resistant and Extended-Spectrum β-Lactamase Gram-Negative Bacteria in Bilateral Lung Transplant Recipientsopens in new tab/window” discourages the use of empirical broad-spectrum antibiotics.

  • Critical Care

A large, multicenter retrospective study, “Inhaled Nitric Oxide vs Epoprostenol During Acute Respiratory Failureopens in new tab/window” finds large variation in the use of inhaled nitric oxide and inhaled epoprostenol during acute respiratory failure across the United StatesA visual abstract for the research can be viewed hereopens in new tab/window.

  • Diffuse Lung Disease

Looking at patients with lymphangioleiomyomatosis, “Impact of Age, Menopause, and Sirolimus on Spontaneous Pneumothoraces in Lymphangioleiomyomatosisopens in new tab/window” research finds increasing age and menopausal status are associated with a reduced risk of development of spontaneous pneumothoraces (SP), and the use of mechanistic target of rapamycin inhibitors is associated with reduced recurrence risk of SPA visual abstract for the research can be viewed hereopens in new tab/window.

CHEST infographic showing diffuse lung disease

What Is the Impact of Age, Menopausal Status, and Sirolimus on Spontaneous Pneumothorax in Lymphangioleiomyomatosis? (Credit: Noella Cortinas, MD, et al. CHEST December 2022, in new tab/window).

  • Thoracic Oncology

The largest study to date on the topic, “Bleeding Risk With Combination Intrapleural Fibrinolytic and Enzyme Therapy in Pleural Infectionopens in new tab/window” shows that, aside from specific scenarios, safety or risk of bleeding alone should no longer be a deterrent to the use of intrapleural fibrinolytic and enzyme therapy in pleural infection. A visual abstract for the research can be viewed hereopens in new tab/window.


Notes for editors

To view the entire December issue of CHEST journal (volume 162, issue 6), published by Elsevier, visit journal.chestnet.orgopens in new tab/window and follow @journal_CHESTopens in new tab/window on Twitter for the latest journal news.

Full text of these articles and interviews with the authors are available to credentialed journalists upon request; contact Laura DiMasi, PR and Communications Specialist, American College of Chest Physicians (CHEST), at [email protected]opens in new tab/window.

About the journal CHEST®

The journal CHESTopens in new tab/window, the official publication of the American College of Chest Physicians®, features the best in peer-reviewed, cutting-edge original research in the multidisciplinary specialties of chest medicine: pulmonary, critical care, and sleep medicine; thoracic surgery; cardiorespiratory interactions; and related disciplines. Published since 1935, it is home to the highly regarded clinical practice guidelines and consensus statements. Access the journal CHEST online at journal.chestnet.orgopens in new tab/window.

About the American College of Chest Physicians

The American College of Chest Physicians® (CHEST) is the global leader in the prevention, diagnosis, and treatment of chest diseases. Its mission is to champion advanced clinical practice, education, communication, and research in chest medicine. It serves as an essential connection to clinical knowledge and resources for its 19,000+ members from around the world who provide patient care in pulmonary, critical care and sleep medicine. For information about the American College of Chest Physicians, and its flagship journal CHEST®, visit in new tab/window

About Elsevier

As a global leader in scientific information and analytics, Elsevier helps researchers and healthcare professionals advance science and improve health outcomes for the benefit of society. We do this by facilitating insights and critical decision-making with innovative solutions based on trusted, evidence-based content and advanced AI-enabled digital technologies.

We have supported the work of our research and healthcare communities for more than 140 years. Our 9,500 employees around the world, including 2,500 technologists, are dedicated to supporting researchers, librarians, academic leaders, funders, governments, R&D-intensive companies, doctors, nurses, future healthcare professionals and educators in their critical work. Our 2,900 scientific journals and iconic reference books include the foremost titles in their fields, including Cell Press, The Lancet and Gray’s Anatomy.

Together with the Elsevier Foundationopens in new tab/window, we work in partnership with the communities we serve to advance inclusion and diversity in science, research and healthcare in developing countries and around the world.

Elsevier is part of RELXopens in new tab/window, a global provider of information-based analytics and decision tools for professional and business customers. For more information on our work, digital solutions and content, visit



Laura DiMasi

PR and Communications Specialist

American College of Chest Physicians (CHEST)

E-mail Laura DiMasi