Best of CHEST® 2023

As a top journal for clinicians across pulmonary, critical care, and sleep medicine, the journal CHEST^® is committed to delivering our readers the latest advancements in chest medicine.

We are excited to share some of our best research, clinical reviews, and guidance from 2023, handpicked by our editorial team. 

Asthma

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  CT Mucus Score and ¹²⁹Xe MRI Ventilation Defects After 2.5 Years’ Anti-IL-5Rα in Eosinophilic Asthma(opens in new tab/window)

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  Albuterol-Budesonide Pressurized Metered Dose Inhaler in Patients With Mild-to-Moderate Asthma: Results of the DENALI Double-Blind Randomized Controlled Trial(opens in new tab/window)

Chest Infections

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  The Changing Epidemiology of Cystic Fibrosis: The Implications for Adult Care(opens in new tab/window)

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  Effect of Corticosteroids on Mortality and Clinical Cure in Community-Acquired Pneumonia: A Systematic Review, Meta-analysis, and Meta-regression of Randomized Control Trials(opens in new tab/window)

COPD

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  Association of Inhaled Corticosteroids With All-Cause Mortality Risk in Patients With COPD: A Meta-analysis of 60 Randomized Controlled Trials(opens in new tab/window)

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  Lung Imaging in COPD Part 1: Clinical Usefulness(opens in new tab/window)

Critical Care

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  High-Dose IV Hydroxocobalamin (Vitamin B12) in Septic Shock: A Double-Blind, Allocation-Concealed, Placebo-Controlled Single-Center Pilot Randomized Controlled Trial (The Intravenous Hydroxocobalamin in Septic Shock Trial)(opens in new tab/window)

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  How We Escalate Vasopressor and Corticosteroid Therapy in Patients With Septic Shock(opens in new tab/window)

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  Respiratory Management of Patients With Neuromuscular Weakness: An American College of Chest Physicians Clinical Practice Guideline and Expert Panel Report(opens in new tab/window)

Diffuse Lung Disease

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  Efzofitimod for the Treatment of Pulmonary Sarcoidosis(opens in new tab/window)

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  Diagnosis and Management of Myositis-Associated Lung Disease(opens in new tab/window)

Education And Clinical Practice

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  Feasibility of a New Lung Ultrasound Protocol to Determine the Extent of Lung Injury in COVID-19 Pneumonia(opens in new tab/window)

Humanities

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  A Case Study in Artificial Intelligence-Generated Manuscripts(opens in new tab/window)

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  A Kind of Faith(opens in new tab/window)

Pulmonary Vascular

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  Evaluation of Dyspnea and Exercise Intolerance After Acute Pulmonary Embolism(opens in new tab/window)

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  The Effects of Exercise Training in Patients With Persistent Dyspnea Following Pulmonary Embolism: A Randomized Controlled Trial(opens in new tab/window)

Sleep

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  Remote Monitoring of Positive Airway Pressure Data: Challenges, Pitfalls, and Strategies to Consider for Optimal Data Science Applications(opens in new tab/window)

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  Polysomnographic Assessment of Sleep Disturbances in Cancer Development: A Historical Multicenter Clinical Cohort Study(opens in new tab/window)

Thoracic Oncology

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  Shape-Sensing Robotic-Assisted Bronchoscopy vs Digital Tomosynthesis-Corrected Electromagnetic Navigation Bronchoscopy: A Comparative Cohort Study of Diagnostic Performance(opens in new tab/window)

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  Pressure-Dependent Pneumothorax and Air Leak: Physiology and Clinical Implications(opens in new tab/window)