Pathway Studio®

Experimental and literature data, pathway analysis and disease models at the heart of biological research

Get started Login to Pathway Studio

Unlock the underlying biology and drive deeper discovery

Find critically relevant and actionable information fast with best-in-class content and powerful analytical tools

Finding actionable insights relating to a particular gene, disease or biomarker requires searching the relevant literature and connecting the disparate pieces of information — often a time-consuming and tedious endeavor. Whether scientists are focused on human pathology or plant biology, an informatics solution that facilitates the interpretation of experimental data gives greater insight into the mechanisms of disease and accelerates biological research through pathway analysis. Pathway Studio is that solution.

By integrating a vast knowledgebase of biological relationships harvested from millions of published articles (full-text and abstracts) with analytical and visualization tools, Pathway Studio enables scientists to explore molecular interactions along with the cause and effect relationships associated with biological processes across multiple organisms. By harnessing the extensive content found beyond the public domain, novel discovery is both more likely and more fully supported. This integrative and comprehensive biology-based investigational framework is ideal for drug target identification, disease modeling, biomarker identification and drug repurposing.

Count on Pathway Studio to help you:

Count on Pathway Studio to help you | Elsevier Solutions

  • Analyze and interpret your experimental results in the context of published data with greater confidence
  • Rapidly develop and confirm experimental hypotheses for new drug targets, biomarkers and drug repurposing projects

Contact us

  • Unravel cell and immunology interactions associated with disease biology
  • Understand the underlying biology that affects development, disease progression and drug responsiveness

Pathway Studio supports however you like to work

Because every researcher and every project has unique data analysis needs, Pathway Studio is flexible in how it you can use it in your work. It supports all common laboratory data formats for proteomics, metabolomics and expression data, including NGS expression (RNA-Seq) as well as NGS variant (VCF) data. So whether you need to run a simple database query to better understand the biology of a specific gene or protein interaction, identify a potential drug target or biomarker, or build a complex disease model, you can easily access the information you need precisely when you need it. For the latest version of Pathway Studio Web, we listened carefully to customer feedback and the result is an even more powerful user interface. These recent upgrades have made Pathway Studio the easiest and fastest solution for understanding the biology of diseases.

Drive more thoughtful, meaningful decisions and research with more molecular interactions and connections

Simplified workflows, manually curated pathways, extensive content and valuable filters empower you to explore molecular interaction data and to identify more connections to your protein, disease or drug. With just a few clicks, biological context — backed by >7 million literature-based molecular interactions and >2,000 manually curated pathways — can be placed around your experimental data. Use of this exhaustive knowledgebase can accelerate innovation across academic, government and corporate institutions by enabling you to:

  • Visualize biological and disease systems through pathway analysis
  • Determine novel drug targets by leveraging published scientific literature (>10,000 journals)
  • Understand the effect of genetic mutations have on patients and on drug development
  • Discern the role of signaling pathways in disease and disease progression
  • Unravel cell and immunology interactions associated with disease biology
  • Discover new diseases your drug can potentially treat

Try Pathway Studio for free

"By giving users the ability to review those relationships, and the corresponding literature sentences, Pathway Studio lets you make those changes on the fly and improve results, including or excluding relationships and assigning correct direction to the regulation." Philip Lorenzi, co-director of the Proteomics and Metabolomics Core Facility, MD Anderson Cancer Center

Read more about MD Anderson Cancer Center (PDF, 573kb)

"[Dr. Castillos] sends me a data file. The profile is imported into the Pathway Studio system and the data is first used to identify which pathways are involved, and then to find the pathways upstream of the genes that caused the change in the tumor’s expression." Dr. Anton Yuryev, Director of Professional Services, R&D Solutions, Elsevier

Read this customer's story (PDF, 601kb)

Bio-IT World Conference & Expo
May 23-25, 2017 Boston, MA

Visit our booth (#161) and attend our talks at Bio-IT:

Wednesday, May 24 at 12:40 pm Luncheon Presentation I: Towards the Use of Bioassays as Predictors of Adverse Events in Clinical Trials
Matthew Clark, Ph.D., Consultant R&D Solutions, Elsevier

HBio-IT World Conference & Expo | Elsevier

Wednesday, May 24 at 5:00 pm Transforming Disparate Data into Collective Insights
Frederik van den Broek, Ph.D., Consultant, R&D Solutions, Elsevier
Gregory Landrum, Ph.D., Vice President, Life Sciences, AG

Learn more

Pathway Studio for free

Please click here if you are interested in a free trial of Pathway Studio.

Explore a sampling of our curated pathways for free.

The Hive: Real Stories. Real Science. Real Time.

Biotech and pharma start-ups are using Elsevier's R&D solutions to solve for early-stage drug discovery and development. To find out more, watch the videos, read real-world case studies and learn how early innovation starts with early access to research.

Visit The Hive

Pharma R&D Today blog

Get a wide range of the latest insights and opinions on pharma-related topics with the Elsevier Pharma R&D blog.

Learn about target identification, big data, new drug discovery, drug safety monitoring, risk mitigation, regulatory compliance and much more.

Visit our pharma blog

Pathway Studio fact sheet

Download (PDF, 1.2mb)

Pathway Studio Plant (PDF, 343kb)

ChemEffect (PDF, 370kb)

DiseaseFX (PDF, 420kb)

CellEffect(TM) (PDF, 1.2mb)

If you have questions about third party licensing or how publishers’ content appears in the product, please contact the Publishing Relations Management team.