Series: Handbook of Clinical Neurology

The Handbook of Clinical Neurology (HCN) was originally conceived and edited by Pierre Vinken and George Bruyn as a prestigious, multivolume reference work that would cover all the disorders encountered by clinicians and researchers engaged in neurology and allied fields. The first series of the Handbook (Volumes 1-44) was published between 1968 and 1982 and was followed by a second series (Volumes 45-78), guided by the same editors, which concluded in 2002. By that time, the Handbook had come to represent one of the largest scientific works ever published.

In 2002, Professors Michael J. Aminoff, François Boller, and Dick F. Swaab took on the responsibility of supervising the third (current) series, the first volumes of which published in 2003. They have designed this series to encompass both clinical neurology and also the basic and clinical neurosciences that are its underpinning. Given the enormity and complexity of the accumulating literature, it is almost impossible to keep abreast of developments in the field, thus providing the raison d'être for the series. The series will thus appeal to clinicians and investigators alike, providing to each an added dimension.

Now, more than 140 volumes after it began, the Handbook of Clinical Neurology series has an unparalleled reputation for providing the latest information on fundamental research on the operation of the nervous system in health and disease, comprehensive clinical information on neurological and related disorders, and up-to-date treatment protocols. Its availability electronically on Elsevier’s ScienceDirect site as well as in print format should ensure its ready accessibility and facilitate searches for specific information. Recognition of the series by the U.S. National Library has allowed abstracts of individual chapters to be obtained through PubMed, increasing their visibility.

Book Series: Aphasia

Most recent volume


Volume 185. Aphasia

Published: 1st April 2022 Editor: Argye Hillis
Aphasia, Volume 185 covers important advances in our understanding of how language is processed in the brain and how lesions or degeneration in the left hemisphere affect language processing. This new release reviews research regarding how language recovers from brain injury, along with new interventions developed to enhance recovery, including language rehabilitation, noninvasive brain stimulation and medications. Sections cover neuroanatomy and neurophysiology of language networks, focus on mechanisms of recovery (and decline) of language, and include chapters on intervention, including recently developed behavioral therapies, brain stimulation, medications, and a review of studies of treatment for both post-stroke aphasia and primary progressive aphasia.

Additional volumes


Volume 184. Neuroplasticity

Published: 1st March 2022 Editors: Angelo Quartarone Maria Ghilardi Francois Boller

Volume 183. Disorders of Emotion in Neurologic Disease

Published: 11th August 2021 Series Volume Editors: Kenneth Heilman Stephen Nadeau

Volume 182. The Human Hypothalamus

Published: 7th July 2021 Editors: Dick Swaab Ruud Buijs Felix Kreier Paul J. Lucassen Ahmad Salehi

Volume 181. The Human Hypothalamus

Published: 4th July 2021 Editors: Dick Swaab Ruud Buijs Paul Lucassen Ahmad Salehi Felix Kreier

Volume 180. The Human Hypothalamus

Published: 1st July 2021 Editors: Dick Swaab Felix Kreier Paul Lucassen Ahmad Salehi Ruud Buijs

Volume 179. The Human Hypothalamus

Published: 15th June 2021 Editors: Dick Swaab Felix Kreier Paul Lucassen Ahmad Salehi Ruud Buijs

Volume 178. Neurology of Vision and Visual Disorders

Published: 6th April 2021 Series Volume Editors: Jason Barton Alexander Leff

Volume 177. Heart and Neurologic Disease

Published: 23rd February 2021 Series Volume Editor: Jose Biller

Volume 176. Interventional Neuroradiology

Published: 1st December 2020 Series Volume Editors: Steven Hetts Daniel Cooke

Volume 175. Sex Differences in Neurology and Psychiatry

Published: 30th September 2020 Series Volume Editors: Rupert Lanzenberger Georg S. Kranz Ivanka Savic

Volume 174. Neurocognitive Development: Disorders and Disabilities

Published: 25th September 2020 Series Volume Editors: Anne Gallagher Christine Bulteau David Cohen Jacques L. Michaud

Volume 172. Neurology and Pregnancy

Published: 5th August 2020 Editors: Eric A.P. Steegers Marilyn J. Cipolla Eliza C. Miller

Volume 171. Neurology and Pregnancy

Published: 29th July 2020 Series Volume Editors: Eric A.P. Steegers Marilyn J. Cipolla Eliza C. Miller

Volume 170. Meningiomas, Part II

Published: 23rd June 2020 Editor: Michael McDermott

Volume 169. Meningiomas, Part I

Published: 16th June 2020 Editor: Michael McDermott

Volume 168. Brain-Computer Interfaces

Published: 10th March 2020 Series Volume Editors: Nick F. Ramsey José del R. Millán

Volume 167. Geriatric Neurology

Published: 19th November 2019 Series Volume Editors: Steven T. DeKosky Sanjay Asthana

Volume 166. Cingulate Cortex

Published: 13th November 2019 Series Volume Editor: Brent Vogt

Volume 165. Psychopharmacology of Neurologic Disease

Published: 12th November 2019 Series Volume Editors: Victor Reus Daniel Lindqvist

Volume 164. Smell and Taste

Published: 8th November 2019 Editor: Richard L. Doty

Volume 163. The Frontal Lobes

Published: 5th October 2019 Series Volume Editors: Mark D'Esposito Jordan Grafman

Volume 173. Neurocognitive Development: Normative Development

Published: 22nd September 2019 Series Volume Editors: Anne Gallagher Christine Bulteau David Cohen Jacques L. Michaud

Volume 162. Neonatal Neurology

Published: 17th July 2019 Series Volume Editors: Linda de Vries Hannah Glass

Volume 161. Clinical Neurophysiology: Diseases and Disorders

Published: 13th July 2019 Series Volume Editors: Kerry Levin Patrick Chauvel

Volume 160. Clinical Neurophysiology: Basis and Technical Aspects

Published: 3rd July 2019 Series Volume Editors: Kerry Levin Patrick Chauvel

Volume 159. Balance, Gait, and Falls

Published: 24th November 2018 Series Volume Editors: Brian Day Stephen Lord

Volume 158. Sports Neurology

Published: 24th November 2018 Series Volume Editors: Brian Hainline Robert Stern

Volume 157. Thermoregulation Part II

Published: 17th November 2018 Series Volume Editor: Andrej A. Romanovsky

Volume 156. Thermoregulation Part I

Published: 16th November 2018 Series Volume Editor: Andrej A. Romanovsky

Volume 155. The Cerebellum: Disorders and Treatment

Published: 8th June 2018 Series Volume Editors: Mario Manto Thierry Huisman

Volume 154. The Cerebellum: From Embryology to Diagnostic Investigations

Published: 8th June 2018 Series Volume Editors: Mario Manto Thierry Huisman

Volume 153. Human Prion Diseases

Published: 7th June 2018 Series Volume Editors: Maurizio Pocchiari Jean Manson

Volume 152. The Neurology of HIV Infection

Published: 29th March 2018 Series Volume Editor: Bruce James Brew

Volume 151. The Parietal Lobe

Published: 5th March 2018 Series Volume Editors: Giuseppe Vallar H. Branch Coslett

Volume 150. Brain Banking

Published: 27th February 2018 Series Volume Editors: Ingeborg Huitinga Maree Webster

Volume 148. Neurogenetics, Part II

Published: 29th January 2018 Series Volume Editors: Daniel H. Geschwind Henry L. Paulson Christine Klein

Volume 147. Neurogenetics, Part I

Published: 8th January 2018 Series Volume Editors: Daniel H. Geschwind Henry L. Paulson Christine Klein

Volume 149. Metastatic Disease of the Nervous System

Published: 4th January 2018 Editors: David Schiff M J Van den Bent

Volume 146. Cerebrospinal Fluid in Neurologic Disorders

Published: 17th November 2017 Series Volume Editors: Florian Deisenhammer Charlotte E. Teunissen Hayrettin Tumani

Volume 145. Neuropathology

Published: 24th October 2017 Serial Volume Editors: Gabor Kovacs Irina Alafuzoff

Volume 144. SPEC – Handbook of Clinical Neurology, Volume 144, Huntington Disease, 12-Month Access, eBook

Published: 22nd September 2017 Series Volume Editors: Andrew S. Feigin Karen E. Anderson

Volume 143. Arteriovenous and Cavernous Malformations

Published: 25th May 2017 Series Volume Editors: Robert Spetzler Karam Moon Rami Almefty

Volume 142. Wilson Disease

Published: 18th April 2017 Editors: Anna Czlonkowska Michael Schilsky

Volume 141. Critical Care Neurology Part II

Published: 25th January 2017 Series Volume Editors: Eelco Wijdicks Andreas Kramer

Volume 140. Critical Care Neurology Part I

Published: 25th January 2017 Series Volume Editors: Eelco Wijdicks Andreas Kramer

Volume 139. Functional Neurologic Disorders

Published: 6th October 2016 Series Volume Editors: Mark Hallett Jon Stone Alan Carson

Volume 137. Neuro-Otology

Published: 13th September 2016 Series Volume Editors: Joseph Furman Thomas Lempert

Volume 138. Neuroepidemiology

Published: 13th September 2016 Series Volume Editors: Caterina Rosano M. Arfan Ikram Mary Ganguli

Volume 136. Neuroimaging, Part II

Published: 12th July 2016 Series Volume Editors: Joseph Masdeu R. Gilberto Gonzalez

Volume 135. Neuroimaging, Part I

Published: 12th July 2016 Series Volume Editors: Joseph Masdeu R. Gilberto Gonzalez

Volume 134. Gliomas

Published: 2nd March 2016 Series Volume Editors: Mitchel Berger Michael Weller

Volume 133. Autoimmune Neurology

Published: 1st January 2016 Series Volume Editors: Sean Pittock Angela Vincent

Volume 132. Neurocutaneous Syndromes

Published: 9th November 2015 Editors: Monica P. Islam E. Steve Roach

Volume 131. Occupational Neurology

Published: 9th November 2015 Series Volume Editors: Marcello Lotti Margit Bleecker

Volume 130. Neurology of Sexual and Bladder Disorders

Published: 15th May 2015 Editors: David Vodusek François Boller

Volume 129. The Human Auditory System

Published: 19th February 2015 Editors: Gastone Celesia Gregory Hickok

Volume 128. Traumatic Brain Injury, Part II

Published: 12th February 2015 Editors: Jordan Grafman Andres Salazar

Volume 127. Traumatic Brain Injury, Part I

Published: 1st February 2015 Editors: Jordan Grafman Andres Salazar

Volume 126. Diabetes and the Nervous System

Published: 5th November 2014 Editors: Douglas Zochodne Rayaz Malik

Volume 125. Alcohol and the Nervous System

Published: 8th October 2014 Editors: Edith Sullivan Adolf Pfefferbaum

Volume 124. Clinical Neuroendocrinology

Published: 28th August 2014 Editors: Eric Fliers Marta Korbonits J.A. Romijn

Volume 123. Neurovirology

Published: 8th July 2014 Editors: Alex Tselis John Booss

Volume 122. Multiple Sclerosis and Related Disorders

Published: 5th February 2014 Editor: Douglas Goodin

Volume 120. Neurologic Aspects of Systemic Disease, Part II

Published: 9th January 2014 Editors: José Biller José Ferro

Volume 119. Neurologic Aspects of Systemic Disease, Part I

Published: 9th January 2014 Editors: José Biller José Ferro

Volume 121. Neurologic Aspects of Systemic Disease, Part III

Published: 9th January 2014 Editors: José Biller José Ferro

Volume 118. Ethical and Legal Issues in Neurology

Published: 7th December 2013 Editors: James L Bernat Richard Beresford

Volume 116. Brain Stimulation

Published: 11th November 2013 Authors: Andres M Lozano Mark Hallett

Volume 117. Autonomic Nervous System

Published: 11th November 2013 Editors: Ruud Buijs Dick Swaab

Volume 115. Peripheral Nerve Disorders

Published: 17th August 2013 Editors: Gérard Said Christian Krarup

Volume 114. Neuroparasitology and Tropical Neurology

Published: 3rd July 2013 Editors: Hector Garcia Herbert Tanowitz Oscar Del Brutto

Volume 111. Pediatric Neurology, Part I

Published: 24th April 2013 Editors: Olivier Dulac Maryse Lassonde Harvey Sarnat

Volume 113. Pediatric Neurology, Part III

Published: 24th April 2013 Series Volume Editors: Olivier Dulac Maryse Lassonde Harvey Sarnat

Volume 112. Pediatric Neurology, Part II

Published: 23rd April 2013 Editors: Olivier Dulac Maryse Lassonde Harvey Sarnat

Volume 110. Neurological Rehabilitation

Published: 5th December 2012 Editors: Michael Barnes David Good

Volume 109. Spinal Cord Injury

Published: 21st November 2012 Editors: Joost Verhaagen John McDonald

Volume 107. Epilepsy, Part I: Basic Principles and Diagnosis

Published: 10th October 2012 Editors: Hermann Stefan William Theodore

Volume 108. Epilepsy, Part II: Treatment

Published: 9th October 2012 Editors: Hermann Stefan William Theodore

Volume 106. Neurobiology of Psychiatric Disorders

Published: 26th June 2012 Editors: Thomas Schlaepfer Charles Nemeroff

Volume 104. Neuro-Oncology Part I

Published: 11th February 2012 Editors: Wolfgang Grisold Riccardo Soffietti

Volume 105. Neuro-Oncology, Part II

Published: 11th February 2012 Authors: Wolfgang Grisold Riccardo Soffietti

Volume 103. Ataxic Disorders

Published: 21st September 2011 Editors: Sankara Subramony Alexandra Dürr

Volume 102. Neuro-ophthalmology

Published: 28th June 2011 Editors: Christopher Kennard R. John Leigh

Volume 101. Muscular Dystrophies

Published: 24th May 2011 Editors: Robert Griggs Anthony Amato

Volume 100. Hyperkinetic Movement Disorders

Published: 23rd May 2011 Editors: William Weiner Eduardo Tolosa

Volume 98. Sleep Disorders Part I

Published: 16th December 2010 Editors: P. Montagna Sudhansu Chokroverty

Volume 99. Sleep Disorders Part II

Published: 15th December 2010 Editors: P. Montagna Sudhansu Chokroverty

Volume 97. Headache

Published: 24th September 2010 Authors: Giuseppi Nappi Michael Moskowitz

Volume 96. Bacterial Infections of the Central Nervous System

Published: 23rd January 2010 Editors: Karen Roos Allan Tunkel

Volume 95. History of Neurology

Published: 8th December 2009 Editors: Stanley Finger François Boller Kenneth Tyler

Volume 92. Stroke Part I: Basic and epidemiological aspects

Published: 17th November 2008 Editor: Marc Fisher

Volume 94. Stroke, Part III: Investigation and management

Published: 12th November 2008 Editor: Marc Fisher

Volume 93. Stroke, Part II: Clinical Manifestations and Pathogenesis

Published: 12th November 2008 Editor: Marc Fisher

Volume 91. Neuromuscular Junction Disorders

Published: 4th August 2008 Editor: A. G. Engel

Volume 89. Dementias

Published: 9th June 2008 Editors: Charles Duyckaerts Irene Litvan

Volume 90. Disorders of Consciousness

Published: 6th June 2008 Editors: G. Bryan Young Eelco Wijdicks

Volume 88. Neuropsychology and Behavioral Neurology

Published: 15th April 2008 Editors: Georg Goldenberg Bruce Miller

Volume 87. Malformations of the Nervous System

Published: 26th September 2007 Editors: Harvey Sarnat Paolo Curatolo

Volume 85. HIV/AIDS and the Nervous System

Published: 16th July 2007 Editors: Peter Portegies Joseph Berger

Volume 86. Myopathies and Muscle Diseases

Published: 16th July 2007 Editors: Frank Mastaglia David Hilton-Jones

Volume 84. Parkinson's Disease and Related Disorders, Part II

Published: 25th June 2007 Authors: William Koller Eldad Melamed

Volume 83. Parkinson's Disease and Related Disorders Part I

Published: 25th June 2007 Editors: William Koller Eldad Melamed

Volume 82. Motor Neuron Disorders and Related Diseases

Published: 1st December 2006 Editors: Andrew Eisen Pamela Shaw

Volume 81. Pain

Published: 10th May 2006 Editors: Fernando Cervero Troels Jensen

Volume 80. Human Hypothalamus: Basic and Clinical Aspects, Part II

Published: 30th December 2003 Author: Dick. F. Swaab

Volume 79. Human Hypothalamus: Basic and Clinical Aspects, Part I

Published: 15th December 2003 Author: Dick. F. Swaab