World Antimicrobial Awareness Week

Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi, and parasites no longer respond to antimicrobial agents. As a result of drug resistance, antibiotics and other antimicrobial agents become ineffective and infections become difficult or impossible to treat, increasing the risk of disease spread, severe illness, and death.

The World Antimicrobial Awareness Week (WAAW) is your chance to be part of a worldwide movement dedicated to combating this urgent crisis. WAAW, observed from November 18th to 24th every year, unites people to raise awareness about AMR and inspire action.

This year's theme emphasizes the importance of collaboration across sectors to safeguard the effectiveness of antimicrobials. It's a call to arms for individuals, communities, healthcare professionals, veterinarians, environmentalists, and policymakers to come together and embrace a shared responsibility. By working collectively, we can make a significant impact.

Here's how you can make a difference:

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  Use antimicrobials wisely and responsibly.

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  Take preventative measures to reduce infection rates.

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  Follow best practices for the disposal of antimicrobial-contaminated waste.

Join us in the fight against AMR during World Antimicrobial Awareness Week 2023. Together, we can protect our health, our planet, and the generations to come. Let's unite for a world free from the threat of drug-resistant infections.

Special Issues

Infection, Disease & Health

Special Issue on Antimicrobial Resistance(opens in new tab/window)

Antimicrobial resistance (AMR) is global health threat. The causes and contributors to AMR vary, but include selective pressures by the overuse of antibiotics, genetic elements and substandard infection prevention and control practices. Infection Disease and Health is primarily concerned with the prevention and control of infections in human health. In this special issue of the journal, we have compiled a selection of articles that are related to one of the biggest challenges of our time – AMR. The articles included in this special issue include a broad range of topics, from antimicrobial stewardship, knowledge and attitudes towards antibiotics, prescribing practices and cost. Articles cover a diverse range of health settings, including hospitals, general practice and broader public health considerations. The special issue provides a great example of how the journal serves as an important platform for health research and uniquely contributes to the infection prevention and control agenda internationally.

International Journal of Infectious Diseases

AMR Collection(opens in new tab/window)

Journal of Infection and Public Health

Special Issue on Antimicrobial Resistance, Stewardship and One Health(opens in new tab/window)

Article collections

Cell Chemical Biology

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  Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance(opens in new tab/window)

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  Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome(opens in new tab/window)

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  Selective killing of the human gastric pathogen Helicobacter pylori by mitochondrial respiratory complex I inhibitors(opens in new tab/window)

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  Overcoming biological barriers to improve treatment of a Staphylococcus aureus wound infection(opens in new tab/window)

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  Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity(opens in new tab/window)

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  Genome- and metabolome-guided discovery of marine BamA inhibitors revealed a dedicated darobactin halogenase(opens in new tab/window)

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Cell Host & Microbe

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  Molecular de-extinction of ancient antimicrobial peptides enabled by machine learning(opens in new tab/window)

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  Multi-armed antibiotics for Gram-positive bacteria(opens in new tab/window)

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  Pulsed antibiotic treatments of gnotobiotic mice manifest in complex bacterial community dynamics and resistance effects(opens in new tab/window)

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  Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria(opens in new tab/window)

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  The resistance within: Antibiotic disruption of the gut microbiome and resistome dynamics in infancy(opens in new tab/window)

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Clinical Infection in Practice

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  Impact of common comorbidities on antimicrobial consumption and mortality amongst critically ill COVID-19 patients: A retrospective two center study in Saudi Arabia(opens in new tab/window)

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  A case of Extensively Drug Resistant (XDR) Extended Spectrum Beta-Lactamase (ESBL) typhoid fever in the Ambulatory Emergency Care (AEC) unit(opens in new tab/window)

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  Efficacy of convalescent plasma therapy in immunocompromised patients with COVID-19: A case report(opens in new tab/window)

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  Pneumococcal prosthetic joint infection – A challenging diagnosis(opens in new tab/window)

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  Oral step-down for Staphylococcus aureus bacteraemia: An opportunity for antimicrobial stewardship?(opens in new tab/window)

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  Prescribing in a pandemic: Electronic prescribing aids to improve non-specialist adherence to COVID-19 guidelines(opens in new tab/window)

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  Impact of common comorbidities on antimicrobial consumption and mortality amongst critically ill COVID-19 patients: A retrospective two center study in Saudi Arabia(opens in new tab/window)

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  30 Determining a potential alternative empirical antibiotic regimen for the treatment of neonatal sepsis in low- and middle-income settings using pre-clinical in vitro techniques(opens in new tab/window)

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  35 The clinical utility of microbiological culture and molecular testing of heart valves in surgically treated infective endocarditis(opens in new tab/window)

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Clinical Microbiology and Infection

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  European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)(opens in new tab/window)

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  Colonization by ceftazidime/avibactam-resistant KPC-producing Klebsiella pneumoniae following therapy in critically ill patients(opens in new tab/window)

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  ESCMID/EUCIC clinical practice guidelines on perioperative antibiotic prophylaxis in patients colonized by multidrug-resistant Gram-negative bacteria before surgery(opens in new tab/window)

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  Antibiotic heteroresistance in ESKAPE pathogens, from bench to bedside(opens in new tab/window)

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  Impact of antibiotic intake on the incidence of extended-spectrum β-lactamase–producing Enterobacterales in sub-Saharan Africa: results from a community-based longitudinal study(opens in new tab/window)

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  Real-world clinical outcome of cefiderocol for treatment of multidrug-resistant non-fermenting, gram negative bacilli infections: a case series(opens in new tab/window)

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  Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance(opens in new tab/window)

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  The emergence of a multidrug resistant Salmonella Muenchen in Israel is associated with horizontal acquisition of the epidemic pESI plasmid(opens in new tab/window)

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  Clinical consequences of very major errors with semi-automated testing systems for antimicrobial susceptibility of carbapenem-resistant Enterobacterales(opens in new tab/window)

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  IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections(opens in new tab/window)

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  How I manage a patient with MRSA bacteraemia(opens in new tab/window)

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  How to: screening for mcr-mediated resistance to colistin(opens in new tab/window)

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Current Opinion in Microbiology

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  Nothing makes sense in drug resistance except in the light of evolution(opens in new tab/window)

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  Interplay of emerging and established technologies drives innovation in natural product antibiotic discovery(opens in new tab/window)

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  Present and future outlooks on environmental DNA-based methods for antibiotic discovery(opens in new tab/window)

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Epidemics

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  Linking antimicrobial prescribing to antimicrobial resistance in the ICU: Before and after an antimicrobial stewardship program(opens in new tab/window)

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  Transmission dynamics of an antimicrobial resistant Campylobacter jejuni lineage in New Zealand’s commercial poultry network(opens in new tab/window)

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Food Microbiology

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  Determination and quantification of microbial communities and antimicrobial resistance on food through host DNA-depleted metagenomics(opens in new tab/window)

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  A five-year study on prevalence and antimicrobial resistance of Campylobacter from poultry carcasses in Poland(opens in new tab/window)

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  Combined metabolomics and transcriptomics analysis reveals the mechanism of antibiotic resistance of Salmonella enterica serovar Typhimurium after acidic stress(opens in new tab/window)

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Infection Prevention in Practice

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  Management of BAME patients with a history of penicillin allergy: barriers to best practice and strategies to overcome these - ScienceDirect(opens in new tab/window)

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  World Antimicrobial Resistance Awareness Week 2023: the overlooked challenges of antimicrobial stewardship - ScienceDirect(opens in new tab/window)

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  Challenges of implementing antimicrobial stewardship tools in Low to Middle Income Countries (LMICs) - ScienceDirect(opens in new tab/window)

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  Antimicrobial resistance as a super wicked problem: how do we engage the public to be part of the solution - ScienceDirect(opens in new tab/window)

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International Journal of Antimicrobial Agents

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  Reducing the duration of antibiotic therapy in surgical patients through a specific nationwide antimicrobial stewardship program. A prospective, interventional cohort study(opens in new tab/window)

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  Changes in the prevalence of pathogens causing hospital-acquired bacterial pneumonia and the impact of their antimicrobial resistance patterns on clinical outcomes: A propensity-score-matched study(opens in new tab/window)

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  Effect of a national antibiotic stewardship intervention in China targeting carbapenem overuse: An interrupted time-series analysis(opens in new tab/window)

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  Antimicrobial resistance surveillance: China's nearly 40-year effort(opens in new tab/window)

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  The battle against fungi: lessons in antifungal stewardship from COVID 19 times(opens in new tab/window)

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  Prescription of antibiotics by general practitioners for patients with a diagnosis of SARS- CoV-2 infection: Analysis of an electronic French health record(opens in new tab/window)

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  Multidrug-resistant Gram-negative bacilli recovered from respiratory and blood specimens from adults: the ATLAS surveillance program in European hospitals, 2018–2020(opens in new tab/window)

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  Geographic patterns of carbapenem-resistant, multi-drug-resistant and difficult-to-treat Acinetobacter baumannii in the Asia-Pacific region: results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) program, 2020(opens in new tab/window)

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  Long-term follow-up of HIV-1 multi-drug-resistant treatment-experienced participants treated with etravirine, raltegravir and boosted darunavir: towards drug-reduced regimen? ANRS CO3 Aquitaine Cohort 2007–2018(opens in new tab/window)

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International Journal of Infectious Diseases

Editorial

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  Antimicrobial resistance – a global problem in need of global solutions(opens in new tab/window)

Research articles

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  Indications and classes of outpatient antibiotic prescriptions in Japan: A descriptive study using the national database of electronic health insurance claims, 2012–2015(opens in new tab/window)

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  Antibiotic use in Kenyan public hospitals: Prevalence, appropriateness and link to guideline availability(opens in new tab/window)

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  Surgical site infections after pancreaticoduodenectomy: Preoperative biliary system interventions and antimicrobial prophylaxis(opens in new tab/window)

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  Effectiveness of ceftazidime–avibactam versus colistin in treating carbapenem-resistant Enterobacteriaceae bacteremia(opens in new tab/window)

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  Emergence of clinical isolates of highly carbapenem-resistant Klebsiella pneumoniae co-harboring blaNDM-5 and blaOXA-181 or -232 in Nepal(opens in new tab/window)

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  In vitro efficacy of ceftazidime-avibactam, aztreonam-avibactam and other rescue antibiotics against carbapenem-resistant Enterobacterales from the Arabian Peninsula(opens in new tab/window)

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  Value of routine whole genome sequencing for Mycobacterium tuberculosis drug resistance detection(opens in new tab/window)

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  High prevalence of ESBL-producing Klebsiella pneumoniae in clinical samples from central Côte d'Ivoire(opens in new tab/window)

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  Clonal expansion of colistin-resistant Acinetobacter baumannii isolates in Cape Town, South Africa(opens in new tab/window)

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  Molecular epidemiology of Carbapenem-resistant Klebsiella pneumoniae in a paediatric hospital in China(opens in new tab/window)

Review

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  Global Antimicrobial Stewardship with a Focus on Low- and Middle-Income Countries(opens in new tab/window)

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  Impact of vaccines on antimicrobial resistance(opens in new tab/window)

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  COVID-19 and antimicrobial stewardship: lessons learned, best practices, and future implications(opens in new tab/window)

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  Global knowledge gaps on antimicrobial resistance in the human health sector: A scoping review(opens in new tab/window)

Perspectives

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  Antibiotics and antimicrobial resistance in the COVID-19 era: Perspective from resource-limited settings(opens in new tab/window)

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iScience

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  Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic(opens in new tab/window)

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  A history of the MetaSUB consortium: Tracking urban microbes around the globe(opens in new tab/window)

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  Metagenomic analysis reveals the dissemination mechanisms and risks of resistance genes in plateau lakes(opens in new tab/window)

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  Bacterial memory in antibiotic resistance evolution and nanotechnology in evolutionary biology(opens in new tab/window)

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  Characterization of a novel genus of jumbo phages and their application in wastewater treatment(opens in new tab/window)

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Journal of Global Antimicrobial Resistance

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  Nosocomial Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella Pneumoniae ST11 in a Medical Intensive Care Unit(opens in new tab/window)

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  Impact of antimicrobial stewardship 2018 on severe pneumonia with bacterial infection in PICU(opens in new tab/window)

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  Emergence of optrA-mediated linezolid resistance in clinical isolates of Enterococcus faecalis from Argentina(opens in new tab/window)

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  Comparison of ANN and LR models for predicting Carbapenem-resistant Klebsiella pneumoniae isolates from a southern province of China's RNSS data(opens in new tab/window)

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  Prevalence of antibiotic resistance of Staphylococcus aureus in cystic fibrosis infection: A systematic review and meta-analysis(opens in new tab/window)

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  Epidemiology of staphylococci species and their antimicrobial-resistance among patients with wound infection in Ethiopia: a systematic review and meta-analysis(opens in new tab/window)

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Journal of Hospital Infection

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  Impact of Intensified Inpatient Clindamycin Stewardship Initiatives in Three Phases: A Pilot Quasi-Experimental Study(opens in new tab/window)

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  The cost-effectiveness of a real-time spatiotemporal mapping surveillance system for meticillin-resistant Staphylococcus aureus prevention(opens in new tab/window)

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  Virulence genes and plasmid replicon profiles of selected β-lactamase-producing Acinetobacter baumannii from orthopaedic patients and the environment in a tertiary referral hospital in Tanzania, East Africa(opens in new tab/window)

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  Swimming pool policies for carriers of highly-resistant micro-organisms receiving rehabilitation care in the Netherlands(opens in new tab/window)

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  Wastewater-based epidemiology for tracking bacterial diversity and antibiotic resistance in COVID-19 isolation hospitals in Qatar(opens in new tab/window)

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  Qualitative analysis of healthcare provider perspectives to evaluating beta-lactam allergies(opens in new tab/window)

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  Modelling hospital disinfectant against multi-drug-resistant dry surface biofilms grown under artificial human sweat(opens in new tab/window)

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  Analysis of carbapenem-resistant strains isolated in a tertiary care hospital in Rawalpindi, Pakistan, during the years 2016 and 2020(opens in new tab/window)

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Journal of Microbiological Methods

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  Evaluation of metagenomic assembly methods for the detection and characterization of antimicrobial resistance determinants and associated mobilizable elements(opens in new tab/window)

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  A rapid MALDI-TOF mass spectrometry-based method for categorization of Pseudomonas aeruginosa from blood cultures as susceptible or resistant to meropenem(opens in new tab/window)

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  Comparison of FT-IR with whole-genome sequencing for identification of maternal-to‑neonate transmission of antibiotic-resistant bacteria(opens in new tab/window)

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Med

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  Refractory Pseudomonas aeruginosa infections treated with phage PASA16: A compassionate use case series(opens in new tab/window)

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Microbes and Infection

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  Nanomotion technology in combination with machine learning: a new approach for a rapid antibiotic susceptibility test for Mycobacterium tuberculosis(opens in new tab/window)

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  Therapeutic potential of kaempferol on Streptococcus pneumoniae infection(opens in new tab/window)

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  Crystal violet decolorization assay: a simplified colorimetric test for the rapid detection of multidrug-resistant Mycobacterium tuberculosis isolates(opens in new tab/window)

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Microbial Risk Analysis

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  Estimating the likelihood of ESBL-producing E. coli carriage in slaughter-aged pigs following bacterial introduction onto a farm: A multiscale risk assessment(opens in new tab/window)

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  Multidirectional dynamic model for the spread of extended-spectrum-B-lactamase-producing Escherichia coli in the Netherlands(opens in new tab/window)

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Microbiological Research

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  The menace of colistin resistance across globe: Obstacles and opportunities in curbing its spread(opens in new tab/window)

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  Genomic insight into the distribution and genetic environment of blaIMP-4 in clinical carbapenem-resistant Klebsiella pneumoniae strains in China(opens in new tab/window)

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Research in Microbiology

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  Analysis of AcrB in Klebsiella pneumoniae reveals natural variants promoting enhanced multidrug resistance(opens in new tab/window)

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  Vancomycin-resistant Enterococcus faecium and the emergence of new sequence types associated with hospital infection(opens in new tab/window)

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  Bacteriophages potentiate the effect of antibiotics by eradication of persister cells and killing of biofilm-forming cells(opens in new tab/window)(opens in new tab/window)

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  Transcription factor mce3R modulates antibiotics and disease persistence in Mycobacterium tuberculosis(opens in new tab/window)

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LabLinks: Antimicrobial resistance