Ir para o conteúdo principal

Infelizmente, não oferecemos suporte total ao seu navegador. Se for possível, atualize para uma versão mais recente ou use o Mozilla Firefox, o Microsoft Edge, o Google Chrome ou o Safari 14 ou mais recente. Se não conseguir e precisar de suporte, envie seu feedback.

Gostaríamos de receber seu feedback sobre essa nova experiência.Diga-nos sua opinião

Elsevier
Publique conosco

Optimize R&D outcomes in pharma & biotech with Elsevier data and tools

Elsevier helps R&D teams make confident drug development decisions. Gain critical insights from innovative AI workspaces and tools built on trusted evidence and domain expertise. R&D teams at 90%+ of the top pharma companies use Elsevier solutions.

Researchers looking toward a computer monitor
  • Trabalhar com a Elsevier tem sido um prazer... Eles forneceram dados que incorporamos ao nosso grafo de conhecimento biomédico proprietário e também oferecem expertise valiosa em ciência de dados e reposicionamento de medicamentos.

    David Fajgenbaum

    Cofundador/Presidente em EveryCure

  • As equipes de P&D precisam de acesso rápido a evidências científicas verificáveis... O LeapSpace promove rigor e transparência ao fornecer citações rastreáveis em suas respostas.

    Victoria Ball

    Diretora Associada de Serviços Globais de Biblioteca em Incyte

  • O Reaxys nos permite consultar e baixar estruturas, vinculá-las a dados de bioatividade e explorar relações estrutura-atividade.... O Reaxys nos dá a confiança de que não perderemos insights críticos.

    Dra. Christine Richardson

    Cientista Principal em Sygnature Discovery

  • Quando você pesquisa no Embase by Elsevier, suas palavras-chave são automaticamente mapeadas para os termos Emtree relevantes... É uma ferramenta essencial para buscas bibliográficas eficazes, garantindo resultados abrangentes e precisos.

    Dra. Katharina Friedrich

    Consultora em Assuntos Regulatórios e Redação Médica

AI-powered R&D solutions for pharma and biotech

Jan Erik Timmermann

Assista agora

|

Elsevier helps pharma and biotech teams bring innovations to market faster with end-to-end risk management. Our R&D solutions include biomedical and chemistry databases, curated datasets, predictive and analytical tools, and a research-grade AI workspace — LeapSpace. LeapSpace unifies key research workflows in one secure environment:

  • Explore complex scientific questions

  • Compare evidence and perspectives

  • Upload and analyze your own documents

  • Identify collaborators and topic experts

Designed to prioritize trust, privacy and security, LeapSpace enables faster discovery with confidence.

Target identification and validation — Is our target druggable?

Science, people and tablet in lab for investigation

Elsevier curates, enriches and connects deep biological and translational data, so you can evaluate target-disease relevance with greater confidence early in discovery. Elsevier data for target identification and validation includes:

  • 18.6M biological relationships

  • Normalized data from ClinicalTrials.gov and public databases

  • Therapeutic area evidence from full-text literature (e.g., oncology, diabetes)

Explore biological, clinical, safety and competitive intelligence data — including early human trials — to identify risks sooner. Elsevier helps teams prioritize high-value targets and improve downstream success rates.

Hit identification to lead optimization — Are we advancing the most promising leads?

Cellular therapy

Elsevier connects chemistry data with biomedical evidence so you can progress confidently from hit identification through lead optimization. Elsevier data for hit identification to lead optimization includes:

  • Detailed experimental procedures for reactions, substances and bioactivities

  • 5.5M extracted safety and PK data lines

Surface ADME, off-target and liability signals to de-risk compounds before committing to a series. Explore structure-activity relationships and integrate biological insights to refine leads with greater precision. Elsevier helps teams prioritize the most promising series and avoid costly late-stage failures.

Preclinical development — Have we surfaced translational risks?

Elsevier helps preclinical teams agree on research strategies with a higher probability of clinical translation by integrating high-quality chemistry, biology and safety evidence. Elsevier data for preclinical development includes:

  • Chemistry and biology data enriched with DMPK, ADME and toxicology research

Explore the chemical space linked to PK and liability trends. Connect targets and pathways to safety concerns, understand toxicity mechanisms and predict potential drug-drug interactions. Elsevier helps teams address safety and developability earlier — before costly experiments begin.

Clinical development — Do we have the evidence needed to de-risk clinical trials?

Female doctor giving instructions about prescription medicine to patient

Elsevier helps clinical development teams design stronger clinical trials with robust safety, feasibility and regulatory evidence. Elsevier data for clinical development includes:

  • Prior trial endpoints, dosing patterns, comparator choices, safety outcomes and translational research

Anticipate exposure- and dose-related risks to reduce costly early-phase rework. Monitor emerging risks across compound classes and competitors to translate preclinical insights into clinical strategies with greater clarity. Elsevier helps teams strengthen trial design and make confident, defensible decisions.

Regulatory approval and post-market surveillance — Are we ahead of safety risks?

View of Earth from space

Elsevier helps pharmacovigilance, regulatory and safety teams detect safety signals earlier and make defensible decisions with regulator-ready evidence. Elsevier data for regulatory approval and post-market surveillance includes:

  • Richly indexed global biomedical literature and regulatory documents for precise, reproducible evidence

Conduct comprehensive literature reviews using full-text journal articles, conference abstracts and grey literature. Monitor adverse events, emerging safety signals and real-world performance with traceable, audit-ready citations. Elsevier helps you detect, assess and validate safety signals with greater speed and rigor.