Aminoff's Neurology and General Medicine

5th Edition

Editors: Michael J. Aminoff S.Andrew Josephson
Hardcover ISBN: 9780124077102
eBook ISBN: 9780124077386
Imprint: Academic Press
Published Date: 3rd April 2014
Page Count: 1392
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Aminoff's Neurology and General Medicine is the standard and classic reference providing comprehensive coverage of the relationship between neurologic practice and general medicine. As neurologists are asked to consult on general medical conditions, this reference provides an authoritative tool linking general medical conditions to specific neurologic issues and disorders. This is also a valuable tool for the general practitioner seeking to understand the neurologic aspects of their medical practice.

Completely revised with new chapters covering metastatic disease, bladder disease, psychogenic disorders, dementia, and pre-operative and post-operative care of patients with neurologic disorders, this new edition will again be the go-to reference for both neurologists and general practitioners.

Key Features

  • The standard authoritative reference detailing the relationship between neurology and general medicine
  • 100% revised and updated with several new chapters
  • Well illustrated, with most illustrations in full color


Clinical neurologists and general medical practitioners

Table of Contents



Preface to the Fifth Edition

Preface to the First Edition

Section I: Respiratory and Cardiovascular Disorders

Chapter 1. Breathing and the Nervous System

Control of Breathing

Evaluation of Pulmonary Function

Patterns of Respiratory Dysfunction

Respiratory Dysfunction from Neurologic Disorders

Disorders of Breathing Associated with Sleep

Neurologic Effects of Respiratory Dysfunction


Chapter 2. Neurologic Complications of Aortic Disease and Surgery

Clinical Neurologic Syndromes Due to Aortic Pathology

Aortic Diseases and Surgery


Chapter 3. Neurologic Complications of Cardiac Surgery

Extracorporeal Circulation

Neurologic Sequelae of Cardiac Surgery

Neurocognitive Decline

Risk Factors for Stroke

Prevention of Neurologic Complications

Cardiac Transplantation


Chapter 4. Neurologic Complications of Congenital Heart Disease and Cardiac Surgery in Children

Neurologic Abnormalities before Cardiac Surgery

Neurologic Injury During Cardiac Surgery

Neurologic Abnormalities in the Postoperative Period


Chapter 5. Neurologic Manifestations of Acquired Cardiac Disease, Arrhythmias, and Interventional Cardiology

Cardiogenic Embolism


Interventional Procedures



Chapter 6. Neurologic Manifestations of Infective Endocarditis

Epidemiology of Neurologic Complications

Pathophysiology of Neurologic Complications

Risk Factors for Neurologic Complications

Ischemic and Hemorrhagic Stroke

Cerebral Infection

Other Neurologic Complications

Suggested Management Algorithm


Concluding Comments




No. of pages:
© Academic Press 2014
Academic Press
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About the Editor

Michael J. Aminoff

Dr. Michael Aminoff was born and educated in England, graduating from University College London in 1962 and as a physician from University College Hospital Medical School in 1965. He subsequently trained in neurology and neurophysiology at The National Hospital (Queen Square) in London, and in 1974 moved to UCSF where he has been Professor of Neurology since 1982. He was Director of the Clinical Neurophysiology Laboratories at UCSF until 2004, when he became Executive Vice Chair of the department of neurology, and also directs the Parkinson’s Disease Clinic and Research Center, a National Parkinson Foundation Center of Excellence. He is the author of more than 230 published medical or scientific articles, as well as the author or editor of some 29 books. His published scientific contributions led to the award of a Doctorate in Science, an advanced doctorate in the Faculty of Science, by the University of London in 2000. He is the one of the two editors-in-chief of the four-volume Encyclopedia of the Neurological Sciences (2nd Edition, Academic Press, 2014), and one of the series editors of the multi-volume Handbook of Clinical Neurology (Elsevier). He was Editor-in Chief of the journal Muscle & Nerve from 1998 to 2007 and serves on numerous other editorial boards. He was a director of the American Board of Psychiatry & Neurology for 8 years, and chair of the board in 2011. Dr. Aminoff has received numerous prizes including the Lifetime Achievement Award of the American Association of Neuromuscular & Electrodiagnostic Medicine in 2006 and the A.B. Baker Award of the American Academy of Neurology for life-time achievements and contributions to medical education in 2007. In 2010, he was awarded the title of “Distinguished Professor” at the University of California, San Francisco. He is married and has three children, one a pediatric rheumatologist, another a federal defense attorney, and the third an assistant district attorney.

Affiliations and Expertise

Distinguished Professor, Department of Neurology, University of California, San Francisco, CA, USA

S.Andrew Josephson

Dr. S. Andrew Josephson is a neurologist who specializes in neurovascular and other neurologic disorders. At UCSF, he cares for general neurology and stroke patients in the hospital as well as in clinic. He is the Director and Founder of the UCSF Neurohospitalist Program and Fellowship, and Medical Director of Inpatient Neurology. He holds the Carmen Castro Franceschi and Gladyne K. Mitchell Neurohospitalist Distinguished Professorship. After graduating from Stanford University, Dr. Josephson earned his medical degree at Washington University in St. Louis. He completed an internship in internal medicine and a residency in neurology at UCSF, where he was chief resident. He also completed fellowships in neurovascular neurology (stroke) and behavioral neurology at UCSF. He is an associate professor of neurology and Vice-Chairman of the Department of Neurology. Dr. Josephson's research interests include improving models of inpatient neurologic care, quality and safety in hospitalized patients, neurologic education, delirium, and the contribution of stroke to dementia. Dr. Josephson has won numerous teaching awards from medical students and residents including being selected to present the keynote speech for the School of Medicine Commencement; the Henry J. Kaiser Award for Excellence in Teaching; the Academic Senate Distinction in Teaching Award, and the Robert Layzer Golden Toe Award for resident teaching.

Affiliations and Expertise

Department of Neurology, University of California, San Francisco, CA, USA


BMA Medical Book Awards 2015: Highly Commended in the Neurology, British Medical Association


"This is a tremendous contribution to the medical literature. It is well written, comprehensive, and replete with many relevant references. There is much to be learned from this presentation, much that has occurred since the previous edition, and much that may be overlooked in the daily practice of medicine, if one is not consciously looking for it. Rating: 5 Stars" --Doody', September 2014