Simplify regulatory searches with PharmaPendium AI
PharmaPendium 支持药物安全性和有效性决策，以获得更好的药物结果
您需要高质量的数据来充满信心地发现、创新和开发。PharmaPendium 将无与伦比的监管和药物数据与全文搜索和预测工具相结合。使用 PharmaPendium 减少动物试验并更快地推出药物。
PharmaPendium在提供临床不良事件信息以及识别非临床研究中的潜在毒性方面至关重要。
Guy Bouvier, 博士，ERT
Groupe Pierre Fabre 的 皮尔法伯集团毒理学和产品安全总监
以高度相关性、精准性和响应速度预测药代动力学药物相互作用至关重要。DDIRC支持快速响应和风险决策。
Yannick Parmentier
Servier 的 生物制药研究部负责人
通过PharmaPendium，我可以了解测量方法，并一键查看来源文件——这对构建稳健、可靠的模型至关重要。
Senior Modeler
Novartis
被 FDA 和世界顶级制药公司使用
做出明智的决策，以提高监管提交的成功率
最大限度地减少监管周期并避免 PharmaPendium 的批准失败。
了解 EMA 和 FDA 的完整监管包，以及 FDA 咨询委员会会议文件
搜索来自FDA、EMA和ICH的全球监管指南，支持合规的药物开发决策
探索以前的监管提交并借鉴先例来预测机构的要求
以已批准和撤回的药物进行基准测试，其作用机制与您的候选药物相同
使用 FDA/EMA 药物批准和审查文件中的比较数据快速响应监管问题
Analyze the toxicity of drug candidates and advance the 3Rs with the new Tox Navigator
Developed in collaboration with Pfizer, Tox Navigator includes toxicity data from regulatory documents and scientific articles.
Supporting the 3Rs and patient safety assessment, the Tox Navigator helps you:
Convert animal doses to human equivalent doses (HEDs)
Leverage existing data to reduce number of animal studies and design more efficient studies
Investigate adverse drug reactions across different species
Integrate in silico models and other non-animal testing methods
Optimize research efforts by focusing on candidates with favorable safety profiles
Connected, configurable solutions to innovate in R&D
Advance your research with Elsevier’s PharmaPendium and a portfolio of solutions for pharmaceutical R&D.
Innovate with confidence, supported by:
Trusted quality information from regulatory data to peer-reviewed scientific literature
Innovative technology that powers data transformation, and analytical and predictive tools
Domain and data science expertise to solve complex problems with data solutions for R&D
Information integrity is essential to your progress. Discover trusted data and tools that deliver critical insights.
Let's shape progress together.
Find precise data to advance your drug portfolio
FDA 和 EMA 文件
FDA 和 EMA 文件
利用 PharmaPendium 的强大功能，提供完整的 FDA 和 EMA 批准包以及重要的 FDA 咨询委员会会议文件，这是其他工具所无法比拟的。
Enhanced visualization
Enhanced visualization
Seamlessly move from table view to interactive charts, graphs and visual aids to easily interrogate and interpret data.
Predictive tools
Predictive tools
Predict harmful DDIs using the DDI Risk Calculator and the risk of off-target adverse events using the Safety Margin Tool.
无与伦比的搜索功能
无与伦比的搜索功能
使用标准化数据按不良事件 （MedDRA）、靶点、适应症、药物和终点查找信息。结果页面弥合了临床前和临床的鸿沟。
来自 FAERS 的真实世界证据
来自 FAERS 的真实世界证据
在 FAERS（FDA 不良事件报告系统）中搜索超过 1900 万份报告，从真实世界证据和上市后药物安全性中查找任何不良事件。
高质量数据集
高质量数据集
PharmaPendium 的高质量数据集可供平台外使用。将数据嵌入到您的工作流程和模型中，以实现更准确的搜索和预测。
... PharmaPendium 擅长检索按药物和物种分类的批准文件中的特定毒性观察结果。
Guy Bouvier, 博士，ERT
Groupe Pierre Fabre 的 皮尔法伯集团毒理学和产品安全总监
Frequently asked questions
PharmaPendium Support CenterContinuous development and improvement of PharmaPendium has been achieved in collaboration with the FDA for 17 years, as well as with leading pharma partners like Novartis, Sanofi, Merck, Servier and Boehringer Ingelheim.
PharmaPendium is used by:
Toxicologists and safety pharmacologists
DMPK specialists
Clinical researchers
Regulatory affairs experts
Global patient safety experts
Data scientists
PharmaPendium provides you with unique content, all in one place. PharmaPendium data sources include:
Full FDA approval packages
Full EMA approval documents
FDA Advisory Committee Documents
FDA Adverse Event Reporting System (FAERS)
FDA classic collection (covering 1938-1991)
DESI (Drug Efficacy Study Implementation) documents
Meyler's 16th Edition
Mosby's Drug Consult™️
Scientific articles
We extract, organize, connect and continually update a wide variety data in PharmaPendium. Get the latest content statistics for PharmaPendium.
PharmaPendium includes safety, PK, MET, efficacy, activity, FAERS and drug data, as well as approval packages and documents from the FDA and EMA.
PharmaPendium and Embase combined empower you to find additional indications for drug repurposing of unapproved or approved drugs. With the breadth of data in Embase and PharmaPendium, you can find relevant clinical studies and data to predict the requirements of clinical trial design and to mitigate risk. In addition to data on approved drugs in PharmaPendium, Embase provides information on unapproved drugs. Embase covers more than 8,500 scientific journals and millions of abstracts from 11,500 conferences worldwide.
Get comprehensive data and innovative tools to analyze drug safety, deliverability and efficacy
