Simplify regulatory searches with PharmaPendium AI
PharmaPendium 支持药物安全性和有效性决策，以获得更好的药物结果
您需要高质量的数据来充满信心地发现、创新和开发。PharmaPendium 将无与伦比的监管和药物数据与全文搜索和预测工具相结合。使用 PharmaPendium 减少动物试验并更快地推出药物。
被 FDA 和世界顶级制药公司使用
Get critical insights to predict the success or failure of drug candidates as early as possible
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To advance the best drug candidates, you want to prove better performance. PharmaPendium has user-friendly tools to help you analyze safety, deliverability and efficacy data.
Predict drug-drug interactions with confidence
Predict the risk of off-target adverse drug reactions (safety margin)
Access data with a translational view across preclinical, clinical and post-market, including:
Preclinical and clinical safety
Animal models
Adverse events (MedDRA)
Pharmacokinetic parameters
Metabolism and transport
Clinical trial and endpoints
Post-market reports (FAERS)
Make informed decisions to increase the success of regulatory submissions
Minimize regulatory cycling and avoid failing approval with PharmaPendium.
Discover complete regulatory packages from the EMA and FDA, and FDA Advisory Committee Meeting Documents
Explore previous regulatory submissions and learn from precedents to predict agencies’ requirements
Benchmark against approved and withdrawn drugs with the same mechanism of action as your drug candidates
Rapidly respond to regulatory questions using comparative data from FDA/EMA drug approval and review documents
Analyze the toxicity of drug candidates and advance the 3Rs with the new Tox Navigator
Developed in collaboration with Pfizer, Tox Navigator includes toxicity data from regulatory documents and scientific articles.
Supporting the 3Rs and patient safety assessment, the Tox Navigator helps you:
Convert animal doses to human equivalent doses
Leverage existing data to reduce number of animal studies and design more efficient studies
Investigate adverse drug reactions across different species
Integrate in silico models and other non-animal testing methods
Optimize research efforts by focusing on candidates with favorable safety profiles
Connected, configurable solutions to innovate in R&D
Advance your research with Elsevier’s PharmaPendium and a portfolio of solutions for pharmaceutical R&D.
Innovate with confidence, supported by:
Trusted quality information from regulatory data to peer-reviewed scientific literature
Innovative technology that powers data transformation and analytical and predictive tools
Domain and data science expertise to solve complex problems with data solutions for R&D
Information integrity is essential to your progress. Discover trusted data and tools that deliver critical insights.
Let's shape progress together.
Find precise data to advance your drug portfolio
FDA 和 EMA 文件
FDA 和 EMA 文件
利用 PharmaPendium 的强大功能，提供完整的 FDA 和 EMA 批准包以及重要的 FDA 咨询委员会会议文件，这是其他工具所无法比拟的。
Enhanced visualization
Enhanced visualization
Seamlessly move from table view to interactive charts, graphs and visual aids to easily interrogate and interpret data.
Predictive tools
Predictive tools
Predict harmful DDIs using the DDI Risk Calculator and the risk of off-target adverse events using the Safety Margin Tool.
无与伦比的搜索功能
无与伦比的搜索功能
使用标准化数据按不良事件 （MedDRA）、靶点、适应症、药物和终点查找信息。结果页面弥合了临床前和临床的鸿沟。
来自 FAERS 的真实世界证据
来自 FAERS 的真实世界证据
在 FAERS（FDA 不良事件报告系统）中搜索超过 1900 万份报告，从真实世界证据和上市后药物安全性中查找任何不良事件。
高质量数据集
高质量数据集
PharmaPendium 的高质量数据集可供平台外使用。将数据嵌入到您的工作流程和模型中，以实现更准确的搜索和预测。
"... PharmaPendium excels in retrieving specific toxicity observations across approval documents categorized by drug and species."
GB
Guy Bouvier, PhD, ERT
Groupe Pierre Fabre 的 Director, Toxicology & Product Safety
Frequently asked questions
PharmaPendium Support CenterContinuous development and improvement of PharmaPendium has been achieved in collaboration with the FDA for 17 years, as well as with leading pharma partners like Novartis, Sanofi, Merck, Servier and Boehringer Ingelheim.
PharmaPendium is used by:
Toxicologists and safety pharmacologists
DMPK specialists
Clinical researchers
Regulatory affairs experts
Global patient safety experts
Data scientists
PharmaPendium provides you with unique content, all in one place. PharmaPendium data sources include:
Full FDA approval packages
Full EMA approval documents
FDA Advisory Committee Documents
FDA Adverse Event Reporting System (FAERS)
FDA classic collection (covering 1938-1991)
DESI (Drug Efficacy Study Implementation) documents
Meyler's 16th Edition
Mosby's Drug Consult™️
Scientific articles
We extract, organize, connect and continually update a wide variety data in PharmaPendium. Get the latest content statistics for PharmaPendium.
PharmaPendium includes safety, PK, MET, efficacy, activity, FAERS and drug data, as well as approval packages and documents from the FDA and EMA.
PharmaPendium and Embase combined empower you to find additional indications for drug repurposing of unapproved or approved drugs. With the breadth of data in Embase and PharmaPendium, you can find relevant clinical studies and data to predict the requirements of clinical trial design and to mitigate risk. In addition to data on approved drugs in PharmaPendium, Embase provides information on unapproved drugs. Embase covers more than 8,500 scientific journals and millions of abstracts from 11,500 conferences worldwide.
Get user-friendly tools to help you analyze drug safety, deliverability and efficacy data
