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Description
The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses.
Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics.
Key Features
Key Features
* Covers all main cytokines and chemokines
* Written by experts
* Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome
* The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters
* Includes major emphasis on clinical applications
* Extensively illustrated with tables and figures
Readership
Research level Immunologists, Pathologists, Cell and Cancer Biologists, Biochemists and Molecular Biologists. Clinicians and Clinical Researchers. Also major market in Pharmaceutical and Biotech Industry. Very significant bulk sales potential. (NB Reachable with use of BiomedSource)
Table of Contents
Volume 1
Preface
Foreward
Section I Basic Cytokine Biology
1 Cytokines Overview
2 Cytokine Genetics
3 The Phylogeny of Cytokines
4 Cytokine Signalling
Section II The Cytokines and Chemokines
Subsection A. The Hematopoietin Family Members
5 Growth Hormone and its Receptors
6 Prolactin
7 Erythropoietin
8 Interleukin 2
9 Interleukin 3
10 Interleukin 4
11 Interleukin 5
12 Interleukin 6
13 Interleukin 7
14 Interleukin 9
15 Interleukin 11
16 Interleukin 12 Family: IL-12
17 Interleukin 13
18 Interleukin 15 and Interleukin 21
19 Interleukin 16
20 Interleukin 17
21 Granulocyte-Macrophage
22 Granulocyte Colony-Stimulating Factor and its Receptor
23 M-CSF Subsection B. The Interferon Family Members
24 Type I Interferons
25 Interferon-g
26 Interleukin 10
27 Interleukins 19, 20, 22, 24 and 26
Volume II.
Subsection C. The beta trefoil cytokines
28 Interleukin 1 a and b
29 Interleukin 1 Receptor Antagonist
30 Novel Interleukin-1 Homologues
31 Interleukin 18
32 The Fibroblast Growth Factors
33 The Hepatocyte Growth Factor The HGF Receptor, MET
34 Toll-like Receptors: The Origins of Inflammation
35 Lymphotoxins
36 Tumor Necrosis Factor
37 TRAIL/apo2L
38 RANK-L : Receptor Activator of NF-kB Ligan
39 CD95L/FasL its receptor CD95 (APO-1/Fas)
40 HMGB-1/Amphoterin
41 EGF Family Ligand
42 FLT3 Ligand
Details
- No. of pages:
- 1572
- Language:
- English
- Copyright:
- © 2003
- Published:
- 22nd April 2003
- Imprint:
- Academic Press
- Print ISBN:
- 9780126896633
- eBook ISBN:
- 9780080518794
About the editors
Angus Thomson
Affiliations and Expertise
Departments of Surgery and Immunology, Thomas E. Starzl Transplantation Institute, University of Pittsburgh Schools of the Health Sciences, Pittsburgh, Pennsylvania, USA
Michael Lotze
Affiliations and Expertise
Departments of Surgery and Bioengineering, University of Pittsburgh Cancer Institute, University of Pittsburgh Schools of the Health Sciences, Pittsburgh, Pennsylvania, USA
Reviews
"Thompson and Lotze are to be commended for compiling this comprehensive work...The editors and authors should be commended for this very difficult task in this rapidly advancing field. There are excellent chapters on cytokine genetics, chemokine nomenclature, and the basic biology of each of the cytokines."
-ASM NEWS (April 2004)