The Cytokine Handbook, Two-Volume Set

The Cytokine Handbook, Two-Volume Set

4th Edition - April 22, 2003

Write a review

  • Editors: Angus Thomson, Michael Lotze
  • eBook ISBN: 9780080518794

Purchase options

Purchase options
DRM-free (PDF, EPub, Mobi)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order


The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics.

Key Features

Key Features
* Covers all main cytokines and chemokines
* Written by experts
* Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome
* The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters
* Includes major emphasis on clinical applications
* Extensively illustrated with tables and figures


Research level Immunologists, Pathologists, Cell and Cancer Biologists, Biochemists and Molecular Biologists. Clinicians and Clinical Researchers. Also major market in Pharmaceutical and Biotech Industry. Very significant bulk sales potential. (NB Reachable with use of BiomedSource)

Table of Contents

  • Volume 1
    Section I Basic Cytokine Biology
    1 Cytokines Overview
    2 Cytokine Genetics
    3 The Phylogeny of Cytokines
    4 Cytokine Signalling
    Section II The Cytokines and Chemokines
    Subsection A. The Hematopoietin Family Members
    5 Growth Hormone and its Receptors
    6 Prolactin
    7 Erythropoietin
    8 Interleukin 2
    9 Interleukin 3
    10 Interleukin 4
    11 Interleukin 5
    12 Interleukin 6
    13 Interleukin 7
    14 Interleukin 9
    15 Interleukin 11
    16 Interleukin 12 Family: IL-12
    17 Interleukin 13
    18 Interleukin 15 and Interleukin 21
    19 Interleukin 16
    20 Interleukin 17
    21 Granulocyte-Macrophage
    22 Granulocyte Colony-Stimulating Factor and its Receptor
    23 M-CSF Subsection B. The Interferon Family Members
    24 Type I Interferons
    25 Interferon-g
    26 Interleukin 10
    27 Interleukins 19, 20, 22, 24 and 26
    Volume II.
    Subsection C. The beta trefoil cytokines
    28 Interleukin 1 a and b
    29 Interleukin 1 Receptor Antagonist
    30 Novel Interleukin-1 Homologues
    31 Interleukin 18
    32 The Fibroblast Growth Factors
    33 The Hepatocyte Growth Factor The HGF Receptor, MET
    34 Toll-like Receptors: The Origins of Inflammation
    35 Lymphotoxins
    36 Tumor Necrosis Factor
    37 TRAIL/apo2L
    38 RANK-L : Receptor Activator of NF-kB Ligan
    39 CD95L/FasL its receptor CD95 (APO-1/Fas)
    40 HMGB-1/Amphoterin
    41 EGF Family Ligand
    42 FLT3 Ligand
    43 Stem Cell Factor
    44 Vascular Endothelial Growth Factor
    45 Macrophage Migration Inhibitory Factor (MIF)46 Interleukin-8 and other CXC Chemokines
    47 C-C Chemokines
    48 Fractalkine-A Cell Surface Chemokines
    49 Transforming Growth Factor b
    50 Inhibin/Activin Family
    51 Bone Morphogenic Proteins
    Section III. Clinical Application of Cytokines and Cytokine Inhibition
    52 Autoimmunity and Cytokines: Pathogenesis and Therapy
    53 Cytokines and Cancer Caligiuri
    54 Interferon alpha: biology, pharmacology, and therapy for chronic viral hepatitis
    55 Haemopoietic Cytokines
    56 Antiangiogenesis
    57 Transplantation
    58 Cytokines and Asthma
    59 Cytokine Gene Transfer
    60 Antisense Therapy
    61 Assays for Cytokines

Product details

  • No. of pages: 1572
  • Language: English
  • Copyright: © Academic Press 2003
  • Published: April 22, 2003
  • Imprint: Academic Press
  • eBook ISBN: 9780080518794

About the Editors

Angus Thomson

Affiliations and Expertise

Departments of Surgery and Immunology, Thomas E. Starzl Transplantation Institute, University of Pittsburgh Schools of the Health Sciences, Pittsburgh, Pennsylvania, USA

Michael Lotze

Affiliations and Expertise

Departments of Surgery and Bioengineering, University of Pittsburgh Cancer Institute, University of Pittsburgh Schools of the Health Sciences, Pittsburgh, Pennsylvania, USA

Ratings and Reviews

Write a review

There are currently no reviews for "The Cytokine Handbook, Two-Volume Set"