The Breast

The Breast

Comprehensive Management of Benign and Malignant Diseases

5th Edition - June 29, 2017

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  • Authors: Kirby Bland, Edward Copeland, V. Suzanne Klimberg, William Gradishar
  • Hardcover ISBN: 9780323359559
  • eBook ISBN: 9780323511872

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Now in a single, convenient volume, The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th Edition covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. Building upon the strengths of previous editions, this updated volume by Drs. Kirby I. Bland, Edward M. Copeland III, V. Suzanne Klimberg, and William J Gradishar, includes the latest innovations in breast cancer detection and treatment in a practical, easy-to-use format ideal for today’s surgeons.

Key Features

  • Delivers step-by-step clinical guidance highlighted by superb illustrations that depict relevant anatomy and pathology, as well as medical and surgical procedures.
  • Reflects the collaborative nature of diagnosis and treatment among radiologists, pathologists, surgeons, oncologists, and other health care professionals who contribute to the management of patients with breast disease.

Table of Contents

  • Section 1: History of the Therapy of Breast Cancer

    1. History of the Therapy of Breast Cancer

    Section 2: Anatomy and Physiology of the Normal and Lactating Breast

    2. Anatomy of the Breast, Axilla, Chest Wall, and Related Metastatic Sites

    3. Breast Physiology: Normal and Abnormal Development and Function

    4. Discharges and Secretions of the Nipple

    Section 3: Benign and Premalignant Lesions

    5. Etiology and Management of Benign Breast Disease

    6. Mastitis and Breast Abscess

    7. Gynecomastia

    8. Benign, High-Risk, and Premalignant Lesions of the Breast

    Section 4: Pathology of Malignant Lesions

    9. In Situ Carcinomas of the Breast: Ductal Carcinoma in Situ and Lobular Carcinoma in Situ

    10. Infiltrating Carcinomas of the Breast: Not One Disease

    11. Mesenchymal Neoplasms and Primary Lymphomas of the Breast

    12. Paget Disease of the Breast

    13. Primary and Secondary Dermatologic Disorders of the Breast

    14. Breast Biomarker Immunocytochemistry

    Section 5: Natural History, Epidemiology, Genetics, and Syndromes of Breast Cancer

    15. Epidemiology of Breast Cancer

    16. Primary Prevention of Breast Cancer

    17. Breast Cancer Genetics: Syndromes, Genes, Pathology, Counseling, Testing, and Treatment

    Section 6: Prognostic Factors for Breast Cancer

    18. Clinically Established Prognostic Factors in Breast Cancer

    19. Molecular Prognostic Factors for Breast Carcinoma

    20. Risk Factors for Breast Carcinoma in Women with Proliferative Breast Disease

    21. Steroid Receptors in Breast Cancer

    Section 7: Molecular Biology of Breast Carcinogenesis

    22. Molecular Oncology of Breast Cancer

    23. Stem Cells in Breast Development and Cancer

    24. Therapeutic Strategies for Breast Cancer

    Section 8: Screening and Diagnosis of Breast Disease

    25. Examination Techniques: Roles of the Physician and Patient in Evaluating Breast Disease

    26. Breast Imaging Screening and Diagnosis

    Section 9: Clinical Trials: Biostatistical Applications

    27. Design and Conduct of Clinical Trials for Breast Cancer

    Section 10: Surgery for Benign and Malignant Diseases of the Breast

    28. Indications and Techniques for Biopsy

    29. General Principles of Mastectomy: Evaluation and Therapeutic Options

    30. Halsted Radical Mastectomy

    31. Modified Radical Mastectomy and Simple Mastectomy

    32. Breast Conservation Therapy for Invasive Breast Cancer

    Section 11: Breast Reconstruction

    33. Breast Reconstruction Techniques

    Section 12: Complications of Breast Surgery

    34. Wound Care and Complications of Mastectomy

    35. Quality Measures and Outcomes for Breast Cancer Surgery

    36. Lymphedema in the Postmastectomy Patient: Pathophysiology, Prevention, and Management

    Section 13: Current Concepts and Management of Early Breast Carcinoma (Tis, Tmic, T1)

    37. Assessment and Designation of Breast Cancer Stage

    38. Biology and Management of Lobular Carcinoma in Situ of the Breast (Lobular Neoplasia)

    39. Ductal Carcinoma in Situ

    40. The New Paradigm: Oncoplastic Breast Conservation Surgery

    41. Therapeutic Value of Axillary Node Dissection and Selective Management of the Axilla in Small Breast Cancers

    42. Lymphatic Mapping and Sentinel Lymphadenectomy for Breast Cancer

    43. Detection and Significance of Axillary Lymph Node Micrometastases

    44. Intraoperative Evaluation of Surgical Margins in Breast-Conserving Therapy

    45. Surgical Management of Early Breast Cancer

    Section 14: Therapy for Stages 0, I, and II Breast Cancer

    46. Biologic Basis of Radiotherapy of the Breast

    47. Radiotherapy and Ductal Carcinoma in Situ

    48. Radiotherapy and Regional Nodes

    49. Postmastectomy Radiotherapy

    50. Breast-Conserving Therapy for Invasive Breast Cancers

    51. Partial Breast Irradiation: Accelerated and Intraoperative

    52. Radiation Complications and Their Management

    53. Radiation Therapy for Locally Advanced Breast Cancer: Historical Review to Current Approach

    54. Adjuvant Endocrine Therapy

    55. Adjuvant and Neoadjuvant Systemic Therapies for Early Stage Breast Cancer

    56. Adjuvant HER2 Therapy

    57. Bisphosphonates in Early Breast Cancer

    58. Oncofertility Options for Young Women with Breast Cancer

    Section 15: Management of Advanced Local, Regional, and Systemic Disease

    59. Surgical Procedures for Advanced Local and Regional Malignancies of the Breast

    60. Solitary Metastases

    61. Locoregional Recurrence after Mastectomy

    62. Principles of Preoperative Therapy for Operable Breast Cancer

    63. Locally Advanced Breast Cancer

    64. Inflammatory Breast Cancer

    65. Neoadjuvant Chemotherapy and Radiotherapy

    66. Detection and Clinical Implications of Occult Systemic Micrometastatic Breast Cancer

    67. Management of the Intact Breast Primary in the Setting of Metastatic Disease

    68. Management of Bone Metastases in Breast Cancer

    69. Chemotherapy and HER2-Directed Therapy for Metastatic Breast Cancer

    70. Endocrine Therapy for Breast Cancer

    71. Immunologic Approaches to Breast Cancer Therapy

    72. Diagnosis and Management of Pleural Metastases in Breast Cancer

    73. Management of Central Nervous System Metastases in Breast Cancer

    74. Management of Pericardial Metastases in Breast Cancer

    Section 16: Special Presentations of Breast Cancer

    75. Bilateral Breast Cancer

    76. Cancer of the Male Breast

    77. Local Recurrence, the Augmented Breast, and the Contralateral Breast

    78. Carcinoma of the Breast in Pregnancy and Lactation

    79. Unknown Primary Presenting with Axillary Lymphadenopathy

    80. Clinical Management of the Patient at Increased or High Risk

    Section 17: Survivorship, Follow-Up Care, and Rehabilitation of the Breast Cancer Patient

    81. General Considerations for Follow-Up

    82. Management of Menopause in the Breast Cancer Patient

    83. Rehabilitation

    84. Psychosocial Consequences and Lifestyle Interventions

    85. Survivorship with Breast Cancer

    Section 18: Medical and Legal Issues Specific to the Care of Breast Cancer

    86. Delayed Diagnosis of Symptomatic Breast Cancer

Product details

  • No. of pages: 1136
  • Language: English
  • Copyright: © Elsevier 2017
  • Published: June 29, 2017
  • Imprint: Elsevier
  • Hardcover ISBN: 9780323359559
  • eBook ISBN: 9780323511872

About the Authors

Kirby Bland

Affiliations and Expertise

Professor and Chairman, Department of Surgery; Deputy Director, UAB Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama

Edward Copeland

Affiliations and Expertise

Emeritus Distinguished Professor, Chairman, Department of Surgery; Director of the Shands Cancer Center, Department of Surgery, University of Florida College of Medicine, Gainsville, Florida

V. Suzanne Klimberg

Affiliations and Expertise

The Courtney M. Townsend, Jr., M.D. Distinguished Chair in General Surgery, Vice Chair for Administration, Professor of Surgery, University of Texas Medical Branch, Galveston, Texas

William Gradishar

Affiliations and Expertise

Betsy Bramsen Professor of Breast Oncology, Professor, Department of Medicine-Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois

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