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Nutrition and Aging - 1st Edition - ISBN: 9780123628756, 9780323138673

Nutrition and Aging

1st Edition

Author: Martha L. Hutchinson
eBook ISBN: 9780323138673
Imprint: Academic Press
Published Date: 22nd December 1986
Page Count: 287
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Nutrition and Aging is a collection of papers presented at the Fifth Bristol-Myers Symposium on Nutrition Research, held in Boston, Massachusetts from October 31 to November 1, 1985. Contributors discuss the significant influence of nutrition on aging, and specifically the role of nutrition in preventing and limiting the physical, mental, and emotional problems associated with the aging process. This book reviews findings that include the effects of the aging process on the body's physiological functions and the effects of nutrient intake on organ function. Consideration is also given to the gap between the documented nutrient intake and nutrient needs of the elderly as it may influence the aging process. The first chapter is a brief overview of the variety of problems that have to be resolved in determining the role of nutrition in aging. The discussion then turns to the relationship of nutrition to changes in physiological function during the aging process, along with factors that influence the nutrient needs of the elderly. The final chapters focus on the impact of nutrition on the etiology of age-related degenerative diseases. This book will be of interest to scientists as well as students and researchers engaged in nutrition research and its growing importance to the prevention and treatment of disease.

Table of Contents


Editor's Foreword



1 Aging and Nutrition: A Multifaceted Problem

I. Introduction

II. Age-Related Changes in Body Composition and Metabolism

III. Aging and Tissue Function

IV. Nutrient Needs and Intakes of the Elderly

V. Factors in the Nutritional Status of the Elderly


2 Physiologic Interface of Aging and Nutrition

I. Introduction

II. Factors Affecting Expression of Disease in the Elderly

III. Physiologie Changes Occurring with Advancing Age

IV. Summary


3 Nutrition and Organ Function in a Cohort of Aging Men

I. Introduction

II. The Baltimore Longitudinal Study of Aging

III. Physiological Functions

IV. Conclusions


4 Impact of Aging and Nutrition on Human Skin: Studies at the Cellular Level

I. Introduction

II. Clinical Aspects of Skin Aging

III. In Vitro Studies of Skin Aging and Nutritional Requirements

IV. Conclusions


5 Vitamin D Synthesis by the Aging Skin

I. Introduction: Consequences of Bone Disease in the Aged

II. Historical Perspective

III. Production of Vitamin D in the Skin

IV. Metabolism of Vitamin D

V. Vitamin D Nutrition in the Aged

VI. Effect of Aging on the Capacity of the Skin to Produce Vitamin D3

VII. Recommendations for Maintaining Vitamin D Nutrition for the Elderly

VIII. Conclusions


6 Implications of Gastric Atrophy for Vitamin and Mineral Nutriture

I. Introduction

II. Physiologic Consequences of Atrophic Gastritis

III. Vitamin B12

IV. Folic Acid

V. Iron

VI. Calcium

VII. Other Micronutrients


7 Trace Elements and the Needs of the Elderly

I. Introduction

II. Definition of Requirement and Recommended Intake

III. The Present State of Knowledge Pertaining to Mineral Requirements of the Elderly

IV. Efficiency of Intestinal Absorption

V. Determination of Requirements for Mineral Elements in the Elderly

VI. The Categories of Mineral Elements

VII. Interactions

VIII. Conclusions


8 Role of Dietary Antioxidants in Aging

I. Introduction

II. Free Radical Theory of Aging

III. Antioxidant Defense Systems

IV. Age-Related Alterations in Antioxidant Protection

V. Life Span Modification by Dietary Antioxidants

VI. Role of Dietary Antioxidants in Degenerative Conditions

VII. Role of Dietary Antioxidants in Immune Function

VIII. Conclusions


9 Aging Animal Models for the Study of Drug-Nutrient Interactions

I. Introduction

II. Basic Aspects of Aging

III. Major Animal Groups for Research on Aging

IV. Drug-Nutrient Interactions in the Elderly

V. Aging and Drug Effects in Animal Models

VI. Drug-Nutrient Interactions in Animal Models

VII. Conclusions


10 Biochemical Assessment of Vitamin Status in the Elderly: Effects of Dietary Supplemental Intakes

I. Introduction

II. Dietary Intake Measurements

III. Vitamin Measurements

IV. Vitamin Assessment in a Healthy Elderly Population

V. Conclusion


11 Effectiveness of Nutrition Intervention Programs for the Elderly

I. Introduction

II. Title III Nutrition Program for Older Americans

III. Food Stamp Program

IV. Other Programs

V. Conclusion


12 The Elderly Alcoholic: Experience with Baltimore Veterans and Private Alcoholism Patients over Age

I. Introduction

II. Prevalence of Alcoholism

III. Amount of Alcohol Ingested

IV. Duration of Alcoholism

V. Diseases Produced by Alcoholism

VI. Discussion


13 Exercise and Muscle Metabolism in the Elderly

I. Introduction

II. Factors Affecting Skeletal Muscle Mass

III. Morphological Changes in Skeletal Muscle

IV. Exercise and Protein Metabolism in Muscle

V. Muscle Metabolism and Aging

VI. Summary


14 Aging of Rats: The Roles of Food Restriction and Exercise

I. Effects of Food Restriction in Rodents

II. Effects of Exercise on Longevity


15 Nutritional Factors in Age-Related Osteoporosis

I. The Problem of Osteoporosis

II. Determinants of Bone Mass

III. Calcium

IV. Phosphate

V. Protein

VI. Vitamin D

VII. Summary and Conclusion


16 Significance of Vitamin D in Age-Related Bone Disease

I. Introduction

II. The Vitamin D Endocrine System

III. Osteomalacia and Osteoporosis

IV. Aging and Vitamin D Metabolism and Function

V. Postmenopausal Osteoporosis

VI. Treatment of Postmenopausal Osteoporosis with l,25-(OH)2D3

VII. Summary


17 Diet, Immunity, and Longevity

I. Introduction

II. Initial Investigations in Mice, Rats, and Guinea Pigs of Protein and Calorie Malnutrition and Immune Functions

III. Zinc and Immunity

IV. Influence of Nutrition on Immunologic Involution and Susceptibility to Diseases of Aging in Inbred Mice

V. Dietary Constituents Crucial to Inhibition of Autoimmunity and Nephritis

VI. Breast Cancer in Mice

VII. Conclusions and Future Studies


18 Nutrition and the Aging Hematopoietic System

I. Introduction

II. Effect of Age on Normal Bone Marrow Function

III. Effect of Age on Hematopoiesis in Man

IV. Epidemiologic Evidence Implicating Nutrition in the Anemia of the Elderly

V. Role of Nutrition in Age-Related Changes in Hematopoiesis in Animals

VI. Hematopoietic Manifestations of Protein-Calorie Malnutrition in the Elderly

VII. Potential Age-Nutrition-Hematopoietic Interactions

VIII. Conclusion


19 Nutrition and the Aging Cardiovascular System

I. Introduction

II. Risk Factors and Aging

III. Secular Trends in Nutrition-Related Risk Factors

IV. Summary




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© Academic Press 1986
22nd December 1986
Academic Press
eBook ISBN:

About the Author

Martha L. Hutchinson

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