Nanomaterials for Biosensors

Nanomaterials for Biosensors

Fundamentals and Applications

1st Edition - October 16, 2017

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  • Authors: Bansi Malhotra, Md. Azahar Ali
  • Hardcover ISBN: 9780323449236
  • eBook ISBN: 9780128135150

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Nanomaterials for Biosensors: Fundamentals and Applications provides a detailed summary of the main nanomaterials used in biosensing and their application. It covers recent developments in nanomaterials for the fabrication of biosensor devices for healthcare diagnostics, food freshness and bioprocessing. The various processes used for synthesis and characterization of nanostructured materials are examined, along with the design and fabrication of bioelectronic devices using nanostructured materials as building blocks. Users will find the fundamentals of the main nanomaterials used in biosensing, helping them visualize a systematic and coherent picture of how nanomaterials are used in biosensors. The book also addresses the role of bio-conjugation of nanomaterials in the construction of nano-biointerfaces for application in biosensors. Such applications, including metal nanoparticles, metal oxide nanoparticles, nanocomposites, carbon nanotubes, conducting polymers and plasmonic nanostructures in biosensing are discussed relative to each nanomaterial concerned. Finally, recent advancements in protein functionalized nanomaterials for cancer diagnostics and bio-imaging are also included.

Key Features

  • Provides a detailed study on how nanomaterials are used to enhance sensing capabilities in biosensors
  • Explains the properties, characterization methods and preparation techniques of the nanomaterials used in biosensing
  • Arranged in a material-by-material way, making it clear how each nanomaterial should be used


Academics and graduate students focusing on the application of nanomaterials in biomedical science, and engineers looking to develop more effective biosensors

Table of Contents

  • 1. Introduction
    1.1  Introduction
    1.2 Nanotechnology and Challenges
    1.3 Biosensors and Nano-electronics Devices
    1.4 Conclusions
    1.5 References    
    2. Synthesis of Nanostructured Materials
    2.1 Introduction
    2.2 Synthesis of metal nanoparticles
    2.3 Synthesis of carbon nanomaterials
    2.4 Synthesis of polymeric nanostructures
    2.5 References

    3. Functionalized Carbon Nanomaterials for Bio-electronics devices
    3.1 Introduction
    3.2 Functionalization of Carbon Nanomaterisl
    3.3 Carbon nanotubes for Biosensors
    3.4 Graphene based Nanoelectronic Bio-devices
    3.5 Graphene oxide based Biosensors
    3.6 Carbon nanofibers Biosensors
    3.7 References

    4.  Bio-conjugated Metal and Semiconductor Nanoparticles for Affinity Bio-devices
    4.1 Introduction
    4.2 Conjugation chemistry for metal nanoparticles
    4.3 Protein conjugated nanoparticles immunosensors
    4.4 References

    5. Surface Bio-functionalization of Metal Oxides: Electrochemical Point of Care Diagnostics
    5.1 Introduction
    5.2 Nanostructured Metal oxides and Properties
    5.3 Electrochemical Biosensors
    5.4 Surface functionalization
    5.5 Role of metal oxides in electrochemical biosensors
    5.6 References

    6. Bio-Polymeric Nanostructures: Biosensors and Bio-Imaging
    6.1 Introduction
    6.2 Conduction Polymer
    6.3 Bio-conjugated Conduction polymer for Biodevics
    6.4 References

    7.  Nanocomposites: Enzymatic Biomoleculer Devices
    7.1 Introduction
    7.2 Nanocomposites
    7.3 Metal oxides- metal nanocomposites
    7.4 Metal- CNTs, Graphene nanocomposites
    7.5 Enzymatic biosensor based on nanocomposites
    7.6 References

    8. Protein Functionalized Nanostructures: Cancer Diagnostics and Fluorescence Imaging
    8.1 Introduction
    8.2 Cancer Diagnostics and Nanomaterials
    8.3 Fluorescence tag nanomaterials for biosensor
    8.4 Nanomaterials for Bio-imaging
    8.5 References

    9.Plasmonic Nanostructures: Fiber Optic Biosensors
    9.1 Introduction
    9.2 Optical Biosensor
    9.3 Plasmonics nanostructured materials
    9.4 Plasmonic Biosensors
    9.5 Nanomaterials based Fiber optic biosensor
    9.6 References 

    10. Nanostructured Biomaterials for In Vivo Biosensors
    10.1 Introduction
    10.2 Biomaterials
    10.3 In Vivo Biosensors and Implantable Biodevices
    10.4 Protein-Corona mediated Nanomaterials
    10.5 Prospects of Nano-biomaterials for Biosensor
    10.6 References

    11. Nanostructured Microfluific Biochip for Bio-Assay Analysis
    11.1 Introduction
    11.2 Fabrication microfluidic devices
    11.3 Microfluidic Biochip
    11.4 Nanomaterials functionalized microfluidic devices
    11.5 Impact of nanomaterials in miniaturization
    11.6 References

    12. Nanomaterials for Whole Cell biosensors
    12.1 Introduction
    12.2 Whole Cell biosensors
    12.3 Microbial sensor
    12.4 Whole-cell bioluminescent biosensors
    12.5 References

    13. Nanostructured Materials for DNA Biochip
    13.1 Introduction
    13.2 DNA biosensors
    13.3 Nanomaterials based biochip fabrication
    13.4 Microarray Biochip
    13.5 Functionalization of DNA with nanomaterials
    13. 6 References

    14. Nanomaterials for pathogen Detection
    14.1 Introduction
    14.2 Biosensors for foodborne pathogens
    14.3 Role of nanomaterials for pathogens detection
    14.4 References    

Product details

  • No. of pages: 332
  • Language: English
  • Copyright: © Elsevier 2017
  • Published: October 16, 2017
  • Imprint: Elsevier
  • Hardcover ISBN: 9780323449236
  • eBook ISBN: 9780128135150

About the Authors

Bansi Malhotra

Bansi Malhotra is a former Professor & Ex-Head, Department of Biotechnoloy, Delhi Technological University, where he established a nanobioelectronics laboratory. He was formally Visiting Professor at the Centre for Nano-Bioengineering & Spintronics, Chungnam National University, South Korea, between 2009 and 2013, and is former Chief Scientist at CSIR-National Physical Laboratory, India. He served as President of the Biosensors Society of India and sits on the advisory boards of numerous international journals. He has previously published three books, and contributed over 340 articles in peer-reviewed journals.

Affiliations and Expertise

Ex-Professor and Head, Nanobioelectronics Laboratory, Department of Biotechnology, Delhi Technological University, Delhi Technological University, India

Md. Azahar Ali

Azahar Ali is a Postdoctoral Research Associate in Electrical and Computer Engineering, Iowa State University, USA. His main focus is looking at the design and fabrication of microfluidic biochips in order to improve biosensor efficiency. He has currently had published over 30 peer-reviewed journal papers

Affiliations and Expertise

Postdoctoral Research Associate in Electrical and Computer Engineering, Iowa State University, USA

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