Inhaled Particles V

Inhaled Particles V

Proceedings of an International Symposium Organized by the British Occupational Hygiene Society, Cardiff, 8-12 September 1980

1st Edition - January 1, 1982

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  • Editor: W. H. Walton
  • eBook ISBN: 9781483150260

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The Annals of Occupational Hygiene: Inhaled Particles V emphasizes respired particles, particularly their effects, fate, and entry, by considering quantitative exposure-effect relationships and basic mechanisms. Divided into eight sections, the book presents analysis of the dynamics of particles that enter the mouth or nose, which has been considered relative to hygiene standards grounded on ‘total dust’. The concerns include the retention of mineral fibers and asbestos in the lungs. The effects on health of coal dusts and fly ash generally common in the energy industries are considered. The text also presents the tests of the carcinogenicity and pathogenicity of dusts and the toxicity of nitrous oxides. The book then focuses on the response of the airways to aerosols, sulfates, gold mine dusts, and organic dusts. Coal mining and its relationship with the progression of pneumoconiosis are also discussed. The book is a great source of information for those who are doing studies in the field of occupational health, particularly on the effects of dust and other related particles on the health of workers.

Table of Contents

  • Preface

    Session 1. Particle Inhalation and Deposition

    Applications of Blunt Sampler Theory to the Definition and Measurement of Inhalable Dust

    Investigations into Defining Inhalable Dust

    Comparison of the Criteria for Sampling 'Inhalable' and 'Respirable' Aerosols

    Particle Deposition within Bronchial Airways: Comparisons Using Constant and Cyclic Inspiratory Flows

    Charge Effects on Particle Deposition in the Human Tracheobronchial Tree

    Generation, Characterization and Inhalation Deposition of Ultrafine Aggregate Aerosols

    Growth Rate Measurements and Deposition Modeling of Hygroscopic Aerosols in Human Tracheobronchial Models

    Pulmonary Penetration and Deposition of Aerosols in Different Gases: Fluid Flow Effects

    Deposition of Particles in the Human Lungs as a Function of Particle Size and Breathing Pattern: an Empirical Model

    Biological Variability of Particle Deposition in the Human Respiratory Tract during Controlled and Spontaneous Mouth-Breathing

    A Quantitative Study of the Penetration of Insoluble Particles into the Tissue of the Conducting Airways

    Implications of the Dosimetric Model for the Respiratory System on Limits for Intakes of Radionuclides by Workers (ICRP PUBLICATION 30)

    Session 2. Deposition, Clearance and Retention

    Deposition of Inhaled Man-Made Mineral Fibers in the Lungs of Rats

    Studies of the Chronic Inhalation of Coal Fly Ash by Rats

    Long-term Inhalation Studies with Raw and Processed Shale Dusts

    Lung Mucociliary Function in Man: Interdependence of Bronchial and Tracheal Mucus Transport Velocities with Lung Clearance in Bronchial Asthma and Healthy Subjects

    Characteristics of Tracheobronchial Deposition and Clearance in Man

    Long-term Particle Clearance in Man: Normal and Impaired

    The Long-term Clearance Kinetics of Insoluble Particles from the Human Lung

    Pulmonary Retention of Coal Dusts

    Translocation of Mineral Fibers through the Respiratory System after Injection into the Pleural Cavity of Rats

    Magnetopneumography as a Tool for the Study of Dust Retention in the Lungs

    Research on Industrial Ferrous Metal Aerosols

    Deposition and Retention of Fibers in the Human Lung

    A Strategy for the Design and Evaluation of a 'Safe' Inorganic Fiber

    Session 3. Dust in Human Lungs

    Multiple Regression Analysis of Quantified Aetiological, Clinical and Post-Mortem Pathological Variables Related to Respiratory Disease in Coal Workers

    The Dust Content of the Lungs of Hard-Rock Miners and its Relationship to Occupational Exposure, Pathological and Radiological Findings

    Asbestos Fibers in the Lungs of Chrysotile Miners and Millers—A Preliminary Report

    Mineral Fiber Content of Lung in Mesothelial Tumors in North America

    A Pathological and Mineralogical Study of Asbestos-Related Deaths in the United Kingdom in 1977

    Session 4. Biological Reactions to Dust

    Prediction of Pneumoconiosis by Bioassays of Particulate from Occupational Exposures

    Silicotic Fibrogenesis: a Concept of Pulmonary Fibrosis

    Increase of RNA and Appearance of New Protein in Silicotic Lung Tissue

    Specific Harmfulness of Respirable Dusts from West German Coal Mines

    I: Results of Cell Tests

    Specific Harmfulness of Respirable Dusts from West German Coal Mines

    II: Results of Intratracheal Tests on Rats

    Specific Harmfulness of Respirable Dusts from West German Coal Mines

    III: Results of Intraperitoneal Tests on Rats

    Specific Harmfulness of Respirable Dusts from West German Coal Mines

    IV: Results of the Quantitative Lymph Node Test

    Specific Harmfulness of Respirable Dusts from West German Coal Mines

    V: Influence of Mineral Surface Properties

    Specific Harmfulness of Respirable Dusts from West German Coal Mines

    VI: Comparison of Experimental and Epidemiological Results

    Variations in Cytotoxicity and Mineral Content between Respirable Mine Dusts from the Belgian, British, French and German Coalfields

    Session 5. Carcinogenic and Cytotoxic Effects

    Comparative Cocarcinogenic Effects of Crocidolite Asbestos, Hematite, Kaolin and Carbon in Implanted Tracheal Organ Cultures

    Variations in the Carcinogenicity of Mineral Fibers

    In Vitro Tests for the Pathogenicity of Mineral Dusts

    Use of an In Vitro Test System to Investigate the Acute and Sub-acute Responses of the Rat Lung to Mineral Dusts

    An Investigation of the Adsorption of Oxides of Nitrogen on Respirable Mineral Dusts and the Effects on their Cytotoxicity

    Effect of Impurities and Associated Minerals on Quartz Toxicity

    In Vitro and In Vivo Studies of Organic Dusts

    Session 6. Airway Response to Aerosols

    Variables Affecting the Outcome of Inhalation of Enzyme Dusts

    Possible Mechanism of Airway Responses in Occupational Exposure to Respiratory Irritants

    Acute Exposure to Gold Mine Dust—a Bronchial Challenge test?

    Effects of Sulphuric Acid Aerosols on Respiratory Tract Airways

    Comparison of Normal and Asthmatic Subjects' Responses to Sulphate Pollutant Aerosols

    Session 7. Individual Factors Determining Pneumoconiosis

    Determinants of Progression in Sandblasters' Silicosis

    Individual Factors in the Development of Coal Miners' Pneumoconiosis

    Session 8. Epidemiological Studies

    A Study of Apparent Anomalies between Dust Levels and Pneumoconiosis at British Collieries

    Studies of Environmental and Host Factors Influencing Personal Differences in Response to Industrial Silica Dust Exposure

    Unusual Pulmonary Observations and Exposure to Coalmine Dust: A Case Control Study

    Irregular Opacities in Coalworkers' Pneumoconiosis—Correlation with Pulmonary Function and Pathology

    The Relation between Pneumoconiosis and Dust Exposure in Spanish Coal Mines with Comparative Studies of Different Gravimetric Dust Samplers

    Coal Miners Exposed to Diesel Exhaust Emissions

    Exposure to Diesel Fumes and Dust at Six Potash Mines

    Respiratory Effects of Prolonged Exposure to Gypsum Dust

    An Epidemiological-Industrial Hygiene Study of Talc Workers

    Carbon Fiber: Results of a Survey of Process Workers and their Environment in a Factory Producing Continuous Filament

    Estimates of Dose-Response for Respiratory Cancer among Chrysotile Asbestos Textile Workers

    Radiological Changes and Fiber Exposure in Chrysotile Workers Aged 60-69 Years at Thetford Mines

    A Mortality Study of Workers Manufacturing Friction Materials with Chrysotile Asbestos

    Health Implications of the Mount St. Helens' Eruption: Epidemiological Considerations

    Health Implications of the Mount St. Helens' Eruption: Laboratory Investigations

    List of Participants

    Author Index

    Subject Index

Product details

  • No. of pages: 964
  • Language: English
  • Copyright: © Pergamon 1982
  • Published: January 1, 1982
  • Imprint: Pergamon
  • eBook ISBN: 9781483150260

About the Editor

W. H. Walton

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