Handbook of Neuro-Oncology Neuroimaging

Remarkable progress in neuro-oncology due to increased utilization of advanced imaging in clinical practice continues to accelerate in recent years. Refinements in magnetic resonance imaging (MRI) and computed tomography (CT) technology, and the addition of newer anatomical, functional, and metabolic imaging methods, such as MRS, fMRI, diffusion MRI, and DTI MRI have allowed brain tumor patients to be diagnosed much earlier and to be followed more carefully during treatment.

With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this second edition of the Handbook of Neuro-Oncology Neuroimaging is so relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuro-Imaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the first edition, and in addition will feature several new important chapters covering diverse topics such as advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. It will also serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology.

• Provides a background to translational research and the use of brain imaging for brain tumors
• Contains critical discussions on the potential and limitations of neuroimaging as a translational tool for the diagnosis and treatment of brain tumor and neuro-oncology patients
• Presents an up-to-date reference on advanced imaging technologies, including computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), as well as the recent refinements in these techniques

Neurosurgeons, neuro-oncologists, neuroradiologists, oncologists, neurologists, and researchers (within oncology and radiology) with an interest in neuroimaging and neuro-oncology

Section I.  Overview of Neuro-Oncological Disorders
1. Overview of Brain Tumor Epidemiology
  Herbert B. Newton
2. Overview of Pathology and Treatment of Primary Brain Tumors
  Herbert B. Newton
3. Overview of Pathology and Treatment of Metastatic Brain Tumors
  Herbert B. Newton
4. Overview of Spinal Cord Tumor Epidemiology
  Herbert B. Newton
5. Overview of Pathology and Treatment of Primary Spinal Cord Tumors
  Herbert B. Newton
6. Overview of Pathology and Treatment of Intramedullary Spinal Cord Metastases
  Herbert B. Newton
7. Epidural Spinal Cord Compression in Adult Neoplasms
  Alicia M. Zukas and David Schiff
8. Neoplastic Meningitis
  Sophie Taillibert, Emilie Le Rhun and Marc C. Chamberlain
9. Vascular Disorders: Epidemiology
  Sylvia Eisele and Lisa Rogers
10. Intracranial Hemorrhage in Cancer Patients
  Chaitra A. Badve and Lisa Rogers
11. CNS Infarction
  Achala Vagal, Arastoo Vossough, Michael H. Lev and Max Wintermark
12. Intracranial Veno-Occlusive Disease
  Chaitra A. Badve and Lisa Rogers
13. Paraneoplastic Syndromes
  Ugonma Chukwueke and Steven Vernino
14. Neoplastic Plexopathies
  Mark A. Ferrante and John T. Kissel
15. Neurologic Complications of Oncologic Therapy
  Isabel Arrillaga-Romany, Michelle Monje and Patrick Wen

Section II.  Physics and Basic Science of Neuro-Imaging
16. Physics of CT: Scanning
  Johannes T. Heverhagen
17. Physics of CT: Contrast Agents
  Ingrid Boehm and Johannes T. Heverhagen
18. Introductory MRI Physics
  Aaron Sodickson and Daniel Sodickson
19. Advanced MR Imaging of Brain Tumors
  Geoffrey S. Young and Jinrong Qu
20. MR Contrast Agents for Neuroradiology: Current Status
  Genevieve Bolles and Maria Vittoria Spampinato
21. Physics of High Field MRI and Applications to Brain Tumor Imaging
  Alayar Kangarlu

Section III.  Advances in Neuro-Imaging of Brain Tumors
22. Magnetic Resonance Image Guided Neurosurgery
  Ferenc Jolesz
23. Neurosurgical Treatment Planning
  Wenya Linda Bi, Olutayo I. Olubiyi, Suzanne Tharin and Alexandra Golby
24. Use of Neuro-Imaging for Radiation Therapy Planning
  Lonika Majithia, Steve Walston, Michael Guiou, Nilendu Gupta and Arnab Chakravarti
25. TTFields Therapy:  Preclinical and Clinical Data
  Joshua Lantos, Robert J. Young, Pedro Cavaleiro Miranda, Cornelia Wenger and Eric T. Wong
26. Applications of Stereotactic Radiosurgery in Neuro-Oncology
  Kunal S. Patel, Paul H. Chapman, Marc Bussiere, Jay Loeffler and Clark C. Chen
27. Diffusion Magnetic Resonance Imaging in Brain Tumors
  L. Celso Hygino da Cruz, Jr. and Margareth Kimura
28. Diffusion Imaging of Brain Tumors
  Stephan E. Maier
29. Functional MRI
  Ryan Fisicaro, Nicole M. Petrovich Brennan and Andrei I. Holodny
30. Magnetic Resonance Spectroscopy
  Tom Mikkelsen, James Snyder and David Hearshen
31. Perfusion Imaging for Brain Tumor Characterization and Assessment of Treatment Response
  Kathleen Schmainda
32. Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Physics
  Marie Foley Kijewski
33. Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging
  Randy Yeh, Vesselin Z. Miloushev and Masanori Ichise
34. Methionine PET - Overview and Application to Brain Tumor Imaging and Treatment
  Arash Kardan and Martin Satter
35. Ultra-High Field Magnetic Resonance Imaging of Brain Tumors
  Gregory A. Christoforidis
36. Neuroimaging of Brain Tumors in Animal Models of CNS Cancer
  Y. Sun and Herbert B. Newton
37. RANO Criteria:  Application to Response Assessment in Clinical Trials 
  Mithun G. Sattur and Michael A. Vogelbaum

Section IV.  Neuro-Imaging of Brain Tumors
38. Malignant Astrocytomas
  A. Drevelegas, D. Chourmouzi, N. Papanicolaou and K. Drevelegas
39. Low Grade Astrocytomas
  John M. Collins and Gregory A. Christoforidis
40. Imaging of Oligodendrogliomas
  William Ankenbrandt and Nina A. Paleologos
41. Primary Central Nervous System Lymphoma
  Herbert B. Newton, H. Wayne Slone and Eric C. Bourekas
42. Pituitary and Sellar region Lesions
  Eric C. Bourekas, Lilja Bjork Solnes and H. Wayne Slone
43. Neoplasms of the Cranial Nerves
  Nicholas C. Ferraro, Michael E. Ivan and Ricardo Jorge Komotar
44. Meningeal tumors
  John M. Collins and Gregory A. Christoforidis
45. Intracranial Schwannomas
  D. Bradley Welling
46. Diencephalic and other deep brain tumors
  A. Drevelegas, D. Chourmouzi, E. Xinou and K. Drevelegas
47. Neuro-Imaging of Glioneuronal Tumors
  Priya Kumthekar and Jeffrey J. Raizer
48. Pineal region tumors
  Edward Yang, Susan Chi and Victoria Michelle Silvera
49. Chordomas and other skull base tumors
  Eric C. Bourekas, Herbert B. Newton and H. Wayne Slone
50. Pediatric brain tumors
  Sanjay P. Prabhu and Tina Y. Poussaint
51. Papillary Glioneuronal Tumors
  Herbert B. Newton, H. Wayne Slone and Eric C. Bourekas
52. Intracranial Metastases
  Arastoo Vossough and John W. Henson
53. Non-Neoplastic mass lesions of the CNS
  S.B. Omay, A. Komli-Kofi and Joachim M. Baehring
54. Neuroimaging Issues in Assessing Response to Brain Tumor Therapy
  Brendan McCullough and John W. Henson
55. Pseudoprogression in Neuro-Oncology: Overview, Pathophysiology, and Interpretation
  Nancy Ann Oberheim Bush, Soonmee Cha, Susan Chang and Jennifer Clarke
56. Pitfalls in the Neuroimaging of Brain Tumors
  Eric C. Bourekas and H. Wayne Slone

Section V.  Neuro-Imaging of Other Neuro-Oncological Syndromes
57. Neuroradiology of Leptomeningeal Metastases
  Emilie Le Rhun, Sophie Taillibert and Marc C. Chamberlain
58. Imaging of Epidural Spinal Cord Compression
  Max Wintermark, David Schiff and Tanvir Rizvi
59. Neuro-imaging for Surgical Treatment Planning of Neoplastic Disease of the Spine
  Carlos Goulart, Tobias A. Mattei, Michael A. Weicker and Ehud Mendel
60. Imaging of Plexopathy in Oncologic Patients
  Andrew D. Schweitzer and George Krol
61. Imaging of Peripheral Neurogenic Tumors
  Randall Lawrence Baldassarre, Ken Alexander Nakanote and Tudor Hesketh Hughes
62. Neuro-Imaging of Cerebrovascular Complications in Cancer Patients
  Prashant Nagpal and Rajan Jain
63. Neuroimaging of Paraneoplastic Syndromes
  Justin Jordan and Steven Vernino