This book contains 182 papers presented at the 12th Symposium of Computer Aided Process Engineering (ESCAPE-12), held in The Hague, The Netherlands, May 26-29, 2002.

The objective of ESCAPE-12 is to highlight advances made in the development and use of computing methodologies and information technology in the area of Computer Aided Process Engineering and Process Systems Engineering.

The Symposium addressed six themes: (1) Integrated Product&Process Design; (2) Process Synthesis & Plant Design; (3) Process Dynamics & Control; (4) Manufacturing & Process Operations; (5) Computational Technologies; (6) Sustainable CAPE Education and Careers for Chemical Engineers. These themes cover the traditional core activities of CAPE, and also some wider conceptual perspectives, such as the increasing interplay between product and process design arising from the often complex internal structures of modern products; the integration of production chains creating the network structure of the process industry and optimization over life span dimensions, taking sustainability as the ultimate driver.


Industries: Chemical industry at large, including bulk petrochemical companies and speciality companies such as pharmaceuticals, polymer companies, food & beverage industries and biotechnology firms.
Institutes/Departments: Chemical engineering, mechanical engineering, physics and maths faculties. Government bodies such as Ministry of Science & Technology Economic Affairs and Sustainable Development.

Table of Contents

Keynote Papers
Sustainable CAPE-education and careers for chemical engineers (B. Drinkenburg). Process synthesis and design in industrial practice (G. Kaibel, H. Schoenmakers). Process software in the chemical industry- the challenge of complexity (J. Kussi et al.). Designing industrial processes for on-aim product quality control (M.L. Luyben). Adaptivity in process systems modeling (W. Marquardt). Plantwide control: towards a systematic procedure (S. Skogestad). Decision confidence - handeling uncertainty through the plant life cycle and datamining (D. Stockill).
Selected Papers. Contributed Papers. Integrated Product and Process Design.
Mass balance and capacity optimisation in the conceptual design of processes for structured products (N.Y. Jadhav et al.). Enzyme conformational predictions by molecular modeling (S.S. Jesus et al.). A modeling formalism for multiproduct and multiplant batch processes (S. Oddone, O.A. Iribarren).
Process Synthesis/Plant Design. Selection of internals for reactive distillation column - case-based reasoning approach (Y. Avramenko et al.). Optimisation-based methodologies for integrating design and control of cryogenic Plants (M. Schenk et al.). Integrated process simulation and CFD for improved process engineering (S.E. Zitney, M. Syamlal).
Process Dynamics and Control. Frequency locking in a discontinuous periodically forced reactor (E. Mancusi et al.). Relational modeling of chemical processes for control logic verification (A.L. Turk, G. Powers). On-line optimal


No. of pages:
© 2002
Elsevier Science
Print ISBN:
Electronic ISBN:

About the editors

J. Grievink

Affiliations and Expertise

Delft University of Technology, Delft, The Netherlands

J. van Schijndel

Affiliations and Expertise

Shell International Chemicals, Amsterdam, The Netherlands