This volume includes papers originally presented at the 7th annual Computational Neuroscience Meeting (CNS'98) held in July of 1998 at the Fess Parker Doubletree Inn in Santa Barbara, California. The CNS meetings bring together computational neuroscientists representing many different fields and backgrounds as well as many different experimental preparations and theoretical approaches. The papers published here range from pure experimental neurobiology, to neuro-ethology, mathematics, physics, and engineering. In all cases the research described is focused on understanding how nervous systems compute. The actual subjects of the research include a highly diverse number of preparations, modeling approaches, and analysis techniques. Accordingly, this volume reflects the breadth and depth of current research in computational neuroscience taking place throughout the world.

Table of Contents

Editorial. Committees. Reviewers. Subcellular. Brief pauses are signals for depressing synapses (Matthias Bethge, Klaus Pawelzik, Theo Geisel). Presynaptic facilitation: Quantal analysis and simulations (Maria Bykhovskaia, Mary Kate Worden, John T. Hackett). Consequence of morphological alterations on synaptic function (Taraneh Ghaffari-Farazi, Jim-Shih Liaw, Theodore W. Berger). Decoding time-varying calcium signals by the postsynaptic biochemical network: computer simulations of molecular kinetics (Yoshihisa Kubota, James M. Bower). Limitations on detection of gradients of diffusible chemicals by axons (J.S. Urbach, Geoffrey J. Goodhill). Cellular. Active dendrites regulate spatio-temporal synaptic integration in hippocampal dentate granule cells (Ildikó Aradi, William R. Holmes). A cellular model of directionally selective visual motion detection in crayfish tangential cells (Annemarie Bartels, Raymon M. Glantz). Dynamics of light-induced current in Hermissenda (K.T. Blackwell). A genetic algorithm study on the influence of dendritic plateau potentials on bistable spiking in motoneurons (Victoria Booth). Finding unstable periodic orbits in electroreceptors, cold receptors and hypothalamic neurons (Hans A. Braun, Mathias Dewald, Karlheinz Voigt, Martin Huber, Xing Pei, Frank Moss). Is there a problem matching real and model CV(ISI)? (David Brown, Jianfeng Feng). New technique for analyzing integrate and fire neurons (A.N. Burkitt, G.M. Clark). Activity-dependent regulation of excitability in rat visual cortical neurons (Niraj S. Desai, Sacha B. Nelson, Gina G. Turrigiano). Effects of dopaminergic modulation of persistent sodium currents on the excitability of prefrontal cortical neurons: a computational study (J.G. Dilmore, B.G. Gutkin, G.B. Ermentrout). Origin of firing varibility of the integrate-and-fire model (Jianfeng Feng). Local cortical injections of glutamate and noradrenaline alter high-frequency (245


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