Clinical and Basic Neurogastroenterology and Motility - 1st Edition - ISBN: 9780128130377, 9780128130384

Clinical and Basic Neurogastroenterology and Motility

1st Edition

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Editors: Satish Rao Yeong Lee Uday Ghoshal
Hardcover ISBN: 9780128130377
eBook ISBN: 9780128130384
Imprint: Academic Press
Published Date: 30th November 2019
Page Count: 660
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Clinical and Basic Neurogastroenterology and Motility is a state-of-the-art, lucidly written, generously illustrated, landmark publication that comprehensively addresses the underlying mechanisms and management of common adult and pediatric motility disorders. These problems affect 50% of the population and include conditions such as dysphagia, achalasia, gastroesophageal reflux disease, gastroparesis, irritable bowel syndrome (IBS), gas and bloating, SIBO, constipation and fecal incontinence. The book brings together international experts and clinician scientists, epitomizing their years of wisdom into a concise yet practical text that is delivered in two distinct sections, basic and clinical. It fulfills a large unmet need, and bridges a long-awaited knowledge gap among trainees, clinicians, scientists, nurses and technicians, earnestly engaged in this field.

Key Features

  • First of its kind text that covers both basic and clinical aspects, bridging the knowledge gap, and providing a bench to bedside approach for management of common disorders
  • Discusses the latest concepts and basic principles of neurogastroenterology and motility, and how the gut and brain interact in the genesis of functional gastrointestinal and motility disorders
  • Provides an illustrated and practical text on hot topics written by leading adult and pediatric gastroenterology experts across the globe
  • Includes an accompanying more detailed web version of the text with free access to future podcasts


Adult and pediatric gastroenterologists, gastrointestinal and colorectal surgeons, internists, basic scientists, gastroenterology fellows and trainees, research scientists, nurses, GI Motility technicians and anyone seeking new knowledge in neurogastroenterology and gastrointestinal motility

Table of Contents

Uday C. Ghoshal

Section 1: Foundations of neurogastroenterology and motility
1. Nerves, smooth muscle cells and interstitial cells in the GI tract: molecular and cellular interactions
Kenton Sanders
2. Gut and brain interactions
Beverley Greenwood-Van Meerveld
3. Neuroimaging and biomarkers in functional gastrointestinal disorders
Jennifer S. Labus and Kirsten Tillisch
4. Gut microbiota and immunology of the gastrointestinal tract
Yongliang Zhang, Yuan-Kun Lee and Grace C A Manley
5. Esophageal anatomy and physiology
Jeff Conklin
6. Gastroduodenal anatomy and physiology
Christopher David Vélez and Braden Kuo
7. Small intestine anatomy and physiology
Zheng Feei Ma and Yeong Yeh Lee
8. Colon and pelvic floor anatomy and physiology
Askin Erdogan and Yeong Yeh Lee
9. Investigation of the brain and gut axis
Shaheen Hamdy and Hamdy Shaheen
10. Neurogastroenterology and motility laboratory: The nuts and bolts
Yeong Yeh Lee and Satish S.C. Rao

Section 2: Diagnostic tests and clinical approaches to neurogastroentereology and motility disorders
11. Deglutition and oropharyngeal dysphagia
Ron Schey and Ammar Nassri
12. Functional dysphagia and globus
Young-Tae Bak
13. Esophageal body motility disorders
Zubair Malik
14. Achalasia
Miguel Angel Valdovinos Sr.
15. Gastroesophageal reflux disorders
Sabine Roman
16. Barrett's, esophageal sensation and reflux
Prateek Sharma
17. Functional heartburn, functional chest pain and reflux hypersensitivity
Abraham Khan
18. Gastroparesis and other gastric motility disorders
Henry Paul Parkman
19. Functional dyspepsia
Sanjiv Mahadeva and Kee-Huat Chuah
20. Nausea, belching and rumination disorders
Richard W. McCallum
21. Investigation of small bowel motility
Edy Soffer
Small Bowel
22. Investigations of dietary malabsorption and gut microbiota
Uday C. Ghoshal
23. Biliary motility and sphincter of Oddi disorders
Nageshwar Reddy and Zaheer Nabi
24. Small intestinal bacterial overgrowth and small intestinal fungal overgrowth
Jigar Bhagatwala and Satish S.C. Rao
25. Investigation of diet, nutrition and gut microbiota
Uday C. Ghoshal
26. FODMAPs and carbohydrate intolerance
Peter Gibson
27. Food allergy and hypersensitivity
Govind K. Makharia
Colon and Anorectum
28. Investigation of anorectal motility
Maura Cosetti
29. Investigation of colonic motility
Maura Cosetti
30. Irritable bowel syndrome
Baharak Moshiree
31. Chronic constipation
Kewin Tien Ho Siah, Kok-Ann Gwee and Alex Soh
32. Dyssynergic defecation and defecatory disorders
Jose Remes-Troche and Mercedes Amieva-Balmori
33. Opioid-induced bowel disorders and narcotic bowel syndrome
Ashok Tuteja
34. Functional diarrhea
M. Masudur Rahman and Uday C. Ghoshal
35. Fecal incontinence
Amol Sharma and Satish S.C. Rao
36. Anorectal pain
Guiseppe Chiarioni
37. Biofeedback therapy
Tanisa Patcharatrakul, Sutep Gonlachanvit and Panyavee Pitisuttithum
Pediatric Neurogastroenterology and motility disorders
38. Neurogastroenterology and motility disorders in pediatric populations
Shaman Rajindrajith
39. Functional gastrointestinal disorders in paediatric populations
Miranda van Tilburg

Section 3: Biopsychosocial and systemic neurogastroenterology and motility
40. Multicultural factors in the treatment of patients with FGIDs
Ami D. Sperber
41. Behavioral and non-pharmacological management of functional gastrointestinal disorders
Sanam Razeghi and Ann Ouyang
42. Probiotics, prebiotics including fiber, medicinal foods and motility
Brooks D. Cash
43. Systemic disorders that affect gastrointestinal motility
Yeong Yeh Lee, Rona Marie Ata


No. of pages:
© Academic Press 2020
30th November 2019
Academic Press
Hardcover ISBN:
eBook ISBN:

About the Editor

Satish Rao

Dr. Satish Rao graduated from Osmania Medical College, Hyderabad, India that was followed by postgraduate training at several UK hospitals. He completed the MRCP (London), and a GI Fellowship and Clinical Research Fellowship from the Royal Hallamshire Hospital, Sheffield and Royal Liverpool Hospitals, Liverpool. He earned his Ph.D. from the University of Sheffield in UK in Neurogastroenterology/Motility and received the distinguished accolade, Fellowship of the Royal College of Physicians, London. He joined the faculty at the University of Iowa in 1991 where he founded the first Center for Neurogastroenterology/Motility in 1995. In 2011, Dr. Rao was recruited to the Medical College of Georgia, Augusta University, as the Founding Director, Digestive Health Center and the GI Service Line, and Chief, Division of Gastroenterology/Hepatology. Currently, he is the Harold J Harrison MD, Distinguished University Chair in Gastroenterology, Professor of Medicine, Director, Digestive Health Clinical Research Center and Director, Neurogastroenterology/Motility. Dr. Rao is past President of the American Neurogastroenterology and Motility Society, Chair of AGA Council in section of Neurogastroentrology and GI Motility. He has received the three highest honors from the American Gastroenterological Association: the Distinguished Clinician Award, the Masters Award for Outstanding Clinical Research and the Distinguished Educator Award. Also a receipient of several distinguished national and international awards and over 100 Distinguished Visiting Professorships, in 2017 he was awarded the Augusta University Distinguished Research Award. He has edited 7 books on GI Motility, received 4 patents, serves on the editorial board of several journals, and has published 500 articles that are widely cited.

Affiliations and Expertise

J. Harold Harrison, MD, Distinguished University Chair in Gastroenterology, Professor of Medicine, Director, Neurogastroenterology & Motility, Director, Digestive Health Clinical Research Center, Augusta University, Augusta, GA, USA

Yeong Lee

Dr. Yeong Yeh Lee graduated from Universiti Sains Malaysia (USM) and continued his post-graduate training in internal medicine in the same institution. After his gastroenterology fellowship with the Ministry of Health of Malaysia, he went on to complete his PhD with Kenneth McColl at Glasgow, United Kingdom. Subsequently he did his post-doctoral fellowship with Satish Rao, co-editor and mentor, at Augusta University but also spent time at the University of North Carolina (UNC) Center for Functional GI & Motility Disorder with an award from the American College of Physicians. Currently, he is Professor of Medicine, Clinical Consultant and Director of GI Function & Motility Lab in his alma mater, USM. Dr. Lee serves as editors of several international journals and steering committee members of Malaysian Society of Gastroenterology and Hepatology, World Gastroenterology Organization and a few regional working groups but also the scientific chairs of meetings including Asian Pacific Digestive Week. He speaks regularly at international and local meetings. Dr. Lee also trained GI fellows and supervised PhDs and post-doctoral fellows. He has received many accolades including the AGA-Moti L. and Kamla Rustgi International Award 2012, the Outstanding Young Malaysian Award 2015 and most recently the Top Research Scientist of Malaysia 2018. He authored and co-authored 7 book chapters and more than 150 highly-cited articles.

Affiliations and Expertise

Professor of Medicine, Senior Consultant of Gastroenterology and Director of GI Function & Motility Lab, Universiti Sains Malaysia

Uday Ghoshal

Dr. Uday C. Ghoshal graduated from the Burdwan Medical College, Burdwan, West Bengal, India in 1986 with University first position in all the three professional examinations and eight gold medals. He did his post-graduation (MD in Internal Medicine) from the Postgraduate Institute of Medical Education and Research, Chandigarh, India in 1991, and subsequently completed his post-doctorate fellowship in Gastroenterology (DM) from the Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India in 1994. After a period of working as a Consultant in the Department of Gastroenterology at the Institute of Post-Graduate Medical Education and Research at Kolkata, West Bengal, India, he joined Sanjay Gandhi Postgraduate Institute of Medical Sciences as Assistant Professor in 2000 where he has been working for the last two decades and is currently Professor in the Dept. of Gastroenterology in the same Institute where he founded and established a well-known Luminal Gastroenterology, GI motility, and functional GI disease unit and laboratory. Dr. Ghoshal founded Asian Neurogastroenterology and Motility Association and the Indian Motility and Functional Diseases Association (currently the President of the latter). He also serves in the several committees of the Rome Foundation, in which, he is currently the Chair of the International Liaison and Research Committees. He is a Fellow of the American College of Gastroenterology, the Rome Foundation, and the National Academy of Medical Sciences (India). He has been invited as a faculty members in several national and international congresses. Dr. Ghoshal also trained a large number of GI fellows and has been guide for several DM and PhD students. He has edited one book on GI Motility, three patents, and serves as Associate Editor and Editorial Board Member of several international journals. Currently he is the Editor-in-Chief of the Indian Journal of Gastroenterology and has published 280 papers that are widely cited. He has received several national and international awards and orations.

Affiliations and Expertise

Professor, Dept. Of Gastroenterolgy, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

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