Advancement of Phenolic Acids in Drug Discovery

Advancement of Phenolic Acids in Drug Discovery

Fundamentals and Applications

1st Edition - October 1, 2023

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  • Editors: Naresh Kumar, Nidhi Goel, Jesus Simal Gandara
  • Paperback ISBN: 9780443185380

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Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers a comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. The first chapter provides and overview of phenolic acids and their characterization. Chapter two discusses the role of phenolic acids in plant systems. Chapter three presents sources and detailed extraction methods of phenolic acids. The following chapters cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book’s final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science, and medicinal chemistry can also benefit of the in-depth profiling of therapeutical properties of phenolic acids.

Key Features

  • Highlights the fundamental concepts with advanced exploration of phenolic acids
  • Provides in depth coverage of design and development of novel drugs from natural phenolic acids
  • Reviews the changing role of phenolic acids i


Graduate students, and researchers working on natural products and their applications in the biomedical and pharmaceutical fields

Table of Contents

  • 1. Introduction
    2. Role of phenolic acids in plant system
    3. Sources and extraction methods of phenolic acids
    4. Phenolic acids as potent antioxidant agents
    5. Phenolic acids based anti-inflammatory and analgesic drugs
    6. Progressive approach of phenolic acids towards the advancement of antimicrobial drugs
    7. Promising role of phenolic acids as anti-malarial and antiviral drugs
    8. Development of phenolic acids-based system as anticancer drugs
    9. Utility of phenolic acids in neurological disorders
    10. Role of Phenolic acids in the treatment of diabetes
    11. Phenolic acids in cardiovascular cure and treatment
    12. Development of phenolic acids based nanocarriers and nanomedicines
    13. Development of metal-phenolic network for biomedical usages
    14. Grand challenges and opportunities for phenolic acids

Product details

  • No. of pages: 640
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: October 1, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780443185380

About the Editors

Naresh Kumar

Dr. Naresh Kumar has received the doctorate in Biotechnology from Indian Institute of Technology Roorkee, Uttarakhand, India. He is currently working as a research scientist at Indian Institute of Technology Indore. He has 12 years of research experience as well as one year teaching experience both at undergraduate and postgraduate level. Chemical biology, Natural Products Chemistry and their biological applications through structural modifications, Drug discovery, are among the major research areas of Dr Kumar. He is a regular reviewer of a variety of international journals from Elsevier, Springer Nature, Taylor & Francis and Academic journals. Dr Kumar has published around 21 international research and review articles in reputed journals along with 03 book chapters. He is also editing a book for Springer Nature and working as guest associate editor for Frontiers in Chemistry: Section (Medicinal and Pharmaceutical Chemistry on the topic entitled “Phenolic Acids: Advances in Drug Discovery”.

Affiliations and Expertise

Research Scientist, Department of Biosciences and Biomedical Engineering, Indian Institute of Technology, Indore, India

Nidhi Goel

Dr. Nidhi Goel is an Assistant Professor at the Department of Chemistry, Institute of Science, Banaras Hindu University, Uttar Pradesh, India. She received her doctorate in Chemistry from the Indian Institute of Technology Roorkee, India, and completed her postdoctoral research at the Indian Institute of Science Bangalore in Karnataka. Dr. Goel’s research focuses on developing strategies, based on supramolecular building approaches, for rational construction of functional coordination polymer, with prospective uses including magnetic, luminescence, and sensing applications. Dr. Goel has published 35 peer-reviewed research papers in reputed international journals and has been the Principal Investigator on 3 research projects from the Government of India. She has 15 years of research experience, along with 4 years of teaching experience at undergraduate and postgraduate level. She has edited 2 books and acts as a regular reviewer for a variety of international journals.

Affiliations and Expertise

Assistant Professor, Department of Chemistry, Institute of Science, Banaras Hindu University, Uttar Pradesh, India

Jesus Simal Gandara

Jesus Simal-Gandara is Full Prof in Nutrition and Food Science at the Faculty of Food Science and Technology, University of Vigo (Spain). He is Corresponding Member of the Royal Academy of Medicine and Surgery of Galicia (1991), Member of the Scientific Committee of the Spanish Agency for Consumption, Food Safety and Nutrition (2013-2016), Research Medal of the Royal Galician Academy of Sciences 2020 Antonio Casares Rodriguez (Chemistry and Geology), President of the International Association of Dietary Nutrition and Safety (2020), Full Member of the Royal Academy of Pharmacy of Galicia (2021), and Associate Editor in Food Science and Nutrition (Wiley) and Food Chemistry (Elsevier). He leads a research group of excellence, and was leading CIA3 - Environmental, Agricultural and Food Research Center (2008-2018). He was the Head of the Department of Analytical Chemistry and Food Science (2013-2018), and Vice-Chancellor for Internationalization at the University of Vigo (2018).

Affiliations and Expertise

Professor in Nutrition and Food Science, Faculty of Food Science and Technology, University of Vigo, Spain

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