2019 Chem-Reaxys 学术周
10月14日 - 南开大学立刻报名
Sunday, October 13, 2019
|12:00 - 17:00||Registration and Check-in（天津水游城假日酒店）（Holiday Inn Tianjin Aqua City）|
|18:30 - 21:30||Dinner|
|Monday, October 14, 2019|
|Session 1 Chair: Professor Weiwei Zi, Nankai University|
|9:00 – 9:15||Welcome Remarks by Prof. Chunming Cui|
|9:15 – 10:00||
New Directions in Palladium/Norbornene Cooperative Catalysis|
Prof. Guanbing Dong, Professor of Chemistry, The University of Chicago
|10:00 – 10:45||
Complex amine synthesis via unusual reactive intermediates|
Prof. Jennifer M. Schomaker, Professor of Chemistry, University of Wisconsin Madison
|10:45 – 11:05||Coffee Break|
|Session 2 Chair: Dr Ji Qi, MSD|
|11:05 – 11:50||Good Enough is Never Good Enough: Innovations in Pharmaceutical Process Development|
Dr. Michael Kress, SVP, Process Research and Development, MSD
|11:50 – 12:05||Reaxys: The Fastest Pathway to Getting the Best Answer|
Sam Yu, Solution Consultant, Elsevier
|12:05 – 14:05||Lunch & Seminar: Empowering Women in Chemistry|
-Seminar by Dr. Caroline McGregor, VP, Analytical Research and Development, MSD
-Panel Discussion: Q&A on career development and diversity in chemistry et al
|Session 3 Chair: Dr Fenglin Liao, Chem|
|14:05 – 14:20||Publishing in Chem from Cell Press|
Dr. Vjekoslav Dekaris, Associate Editor, Chem
|14:20 - 14:55||
Strategy for Synthesis of Complex Peptides and Carbohydrates|
Prof. Gong Chen, Nankai University
|14:55 – 15:30||
Biorthogonal protein activation in space and time: from living cells to living animals|
Prof. Peng Chen, Peking University
|15:30 – 15:50||Coffee Break|
|Session 4 Chair: Dr. Vjekoslav Dekaris, Chem|
|15:50 – 16:25||Rationally Driven Evolution of Chiral Bio-inspired Catalysis|
Prof. Sanzhong Luo, Tsinghua University
|16:25 – 17:00||Artificial Photosynthetic Systems for Chemical Transformation|
Prof. Li-Zhu Wu, Technical Institute of Physics and Chemistry, CAS
|17:00 – 17:45||Electron Catalysis|
Prof. Armido Studer, Professor of Organic Chemistry, Westfälische Wilhelms-Universität Münster
|17:45 – 17:55||Closing Remarks by Anmin Xiang|
Professor of Chemistry, The University of Chicago
Dr. Guangbin Dong received his B.S. degree from Peking University and completed his Ph.D. degree in Chemistry from Stanford University with Professor Barry M. Trost. In 2009, He joined the group of Prof. Robert H. Grubbs at California Institute of Technology, as a postdoctoral researcher. His expertise is in the field of organic synthesis, catalysis, organometallics and medicinal chemistry. His future research interests lie at the development of powerful chemical tools for addressing questions of biological importance. His research program will bring together the complimentary knowledge of organic synthesis, medicinal chemistry and organometallic chemistry in collaboration with scientists in the field of cellular biology and animal pharmacology to identify effective small-molecule agents that target new molecular mechanisms for cancer treatment.
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Dr. Dong’s Ph.D. research studies involved development of new catalytic enantioselective synthetic methods and applied these methods in the total syntheses of biologically important molecules. The majority of the natural products Dr. Dong synthesized exhibit high potent anticancer activity, such as agelastatin A, terpestacin, and bryostatins. In addition, he has designed and synthesized a new bryostatin analogue; in collaboration with Genetech, this agent has show nanomolar anticancer activity again several cancer cell lines. This work has been published in Nature.
At California Institute of Technology, Dr Dong was a Camille and Henry Dreyfus Environmental Chemistry Fellow in the group of Professor Robert H. Grubbs. His research aimed at development of catalysts for anti-Markovnikov hydration of olefins, considered as one of the top 10 challenges in catalysis. Dr. Dong developed the first reproducible anti-Markovnikov olefin hydration process using a dual-metal system.
Dr. Dong's primary goal as an advisor is to give graduate students and postdocs with professional training that will assist them for their future careers as independent researchers. He will create a healthy environment where both students and postdocs are able to share experiences and knowledge with each other. The key is to offer each group member sufficient freedom to explore on his/her own. They should be allowed to make their own mistakes and correct themselves by finding their own solutions. They will be encouraged to talk more to each other and learn from each other. Meanwhile, he will be around and ready to give suggestions. Dr. Dong believe that such a collaborative environment would be beneficial for students and postdocs to develop into thoughtful scientists capable of conducting research on an independent level.
Jennifer M Schomaker
Professor of Chemistry, The University of Wisconsin-Madison
Professor Schomaker began her research career at Dow Chemical in Organic Chemicals and Polymers, later moving to Agricultural Chemicals Process Research, where she participated in the route selection and scale-up campaigns for two new herbicides. After nearly 7 years in industry, she returned to academia, obtaining her Ph.D. with Professor Babak Borhan at Michigan State University in 2006 before moving to UC-Berkeley as an NIH postdoctoral fellow in the labs of Professors Robert G. Bergman and F. Dean Toste.
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She joined the faculty at the University of Wisconsin-Madison in 2009, where her research focuses on new methodologies for the preparation of stereochemically complex, densely functionalized amines, catalyst-controlled, tunable chemo- and site-selective C-H functionalizations, uncovering new reactivities catalyzed by first-row transition metals, the total synthesis of bioactive natural and unnatural products, and development of new bioorthogonal labeling reagents. Her awards include the NSF-CAREER, Sloan Research Fellowship, Thieme Chemistry Journal Award, ACS-WCC Rising Star Award, ACS DOC Early Academic Investigator Award, MSU Distinguished Alumni Award, and UW-Vilas Mid-Career and UW2020 Awards. She was named a Kavli Fellow and recently received a Gabor A. and Judith K. Somorjai Visiting Miller Professorship Award from UC-Berkeley.
Professor of Organic Chemistry, Westfälische Wilhelms-Universität Münster
Professor Armido Studer studied chemistry at the ETH Zürich, Switzerland, and gained his Ph.D. from there in 1995, under the guidance of Professor Dieter Seebach. From 1995–1996, he performed postdoctoral studies at the University of Pittsburgh, USA, in the group of Professor Dennis Curran. Studer did his Habilitation at the Laboratory of Organic Chemistry, ETH Zürich, on the development of new synthetic methods in the field of free radical chemistry.
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In 2000, he was appointed Associate Professor of Organic Chemistry at the Philipps-Universität Marburg, Germany, and in 2004, as Full Professor (C4) of Organic Chemistry at the Westfälische Wilhelms-Universität Münster, Germany.Since 2009, he has been Full Professor (W3) of Organic Chemistry at the Westfälische Wilhelms-Universität Münster.
Michael H. Kress
Senior Vice President, Process Research and Development, MSD
Dr. Kress received his B.S. in Chemistry from the Pennsylvania State University. Upon graduation Mike joined the laboratory of Professor Yoshito Kishi at Harvard, where his research focused on the total synthesis of members of the taxane diterpene family. Upon receiving his Ph.D. Mike accepted the position of Sr. Research Chemist within the MSD Process Research group where his research focused on the development of efficient synthetic processes to a variety of drug development targets within MSD's diabetes (PPAR) and pain franchises (BK-1, Nav-1.7).
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In 2006 Mike accepted the position of Senior Director of Worldwide Process Research at Cephalon, Inc. While at Cephalon, Mike’s research interests were focused on the enantioselective Kagan oxidation of prochiral sulfides, and efficient manufacturing routes to stuarosporin-like PKC inhibitors.
Mike returned to MSD as Executive Director of Pharmaceutical Development in 2007, and was promoted to the position of Vice President of Pharmaceutical Research and development in early 2008. During his tenure within drug product development Mike collaborated to support a number of key development programs and product launches, including: Janumet XR, Belsomra, Zepatier.
In 2013 Mike accepted the position of Vice President of MSD’s small molecule Process Research and Development (PRD) team, and in 2018 was promoted into his current role to lead Process Research and Development activities across the small molecule, biologics and vaccines modalities. Mike is a member of the American Chemical Society, the American Association of Pharmaceutical Scientists, and the Innovation and Quality Consortia.
Vice President, Analytical Research & Development, MSD
Dr. Caroline McGregor is Vice President, Analytical Research & Development and has been in her current role since April 2018. In this role, she leads a group of managers & scientists committed to effective execution on the MSD pipeline from Discovery through filing and launch by delivering integrated physical, analytical and bioanalytical solutions and through application of innovative technologies while leveraging critical network collaborations, and interactions with the external scientific and regulatory communities. This includes all modalities, small molecules, biologics & vaccines.
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Caroline's career with MSD began in 2001 as a preformulation scientist in Pharmaceutical Sciences with a focus on bringing pharmaceutical sciences and drug delivery expertise to Discovery and Early Development. She led teams covering all aspects of physical characterization to support salt and polymorph selection as well as development of formulations which optimize exposure and duration of action for preclinical PK, efficacy and toxicology studies. She has held positions of increasing responsibility during her tenure. She was Director & Site Lead for Discovery Pharmaceutical Sciences in Boston for 5 years and was Executive Director Discovery Pharmaceutical Sciences for 2 years prior to moving to Process Research & Development in 2015. Initially the scope of this role was leading Analytical Chemistry with a focus on analytical development for small molecule active pharmaceutical ingredients which was then expanded her current scope in Analytical Research & Development.
Caroline was educated at the University of Strathclyde in Glasgow, Scotland, where she graduated in 1998 with a BSc in Chemistry. In 2001, she received her PhD in Chemistry from the University of Cambridge for a thesis which focused on design of novel liposomal drug delivery systems for DNA and small molecules. She is the author of various publications in the fields of characterization of pharmaceutical materials and drug delivery.
Professor of Basic Molecular Science Center, Department of Chemistry, Tsinghua University
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Proferssor of Chemistry, Nankai University
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2015年起，在南开大学元素有机化学国家重点实验室全职工作，任教授、博士生导师。课题组主要从事复杂糖肽类化合物的有机合成及其化学生物学的研究。独立工作以来，在J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nature Chem. Nature Catal.等学术刊物上发表学术论文70多篇。 先后获得US-NSF CAREER奖、 Amgen Young Investigator奖、 药明康德生命化学研究学者奖，和国家基金委杰出青年基金等奖项。
Professor, Peking University
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2012年度国家杰出青年基金获得者，2015年成为基金委创新研究群体学术带头人，2017年度教育部长江学者特聘教授。曾获国际生物无机化学会早期职业奖（SBIC Award, 2017),陈嘉庚青年科学奖（2016）、教育部青年科学奖（2016）等荣誉, 目前担任ACS Chemical Biology副主编。
Professor at the Technical Institute of Physics and Chemistry, Chinese Academy of Sciences
吴骊珠，博士，研究员，博士生导师，中国科学院理化技术研究所超分子光化学研究中心主任，科技委委员。长期致力于超分子体系中的光诱导电子转移、能量传递和化学转换研究，在人工光合成作用、可见光催化有机合成反应、重要的光物理和光化学过程等研究中取得了系列创新性成果。已在国际化学领域重要学术期刊(包括Acc. Chem. Res.，Nature Rev. Chem., Nature Commun. ，Angew. Chem. Int. Ed., J. Am. Chem. Soc., Energy Environ. Sci., Adv. Mater.)上发表SCI论文300余篇。
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担任Journal of Materials Chemistry A副主编、ChemCatChem编委、《化学学报》编委等。2001年获得国家自然科学基金“杰出青年基金”资助，结题被评为优秀并获中国科学院“百人计划”（2006）后续支持，2004年入选“新世纪百千万人才工程国家级人选”，2005年获得国家自然科学二等奖1项（第二完成人）。2007年荣获“第十届中国青年科技奖”，2009年荣获“第三届中国科学院十大杰出妇女”，2010年荣获“第七届中国青年女科学家”奖，2011年荣获“中国科学院朱李月华优秀教师奖”，2013年荣获“中国化学会-物理有机化学奖”，2016年荣获“第三届中国化学会-赢创化学创新奖”，2016年入选第二批国家“万人计划”百千万工程领军人才，2017年荣获“中国科学院优秀导师奖”，2017年当选为英国皇家化学会会士。