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Best of JACC and the JACC specialty journals

Featuring the most-cited papers and most talked about articles in the cardiovascular research community

We’ve compiled the top articles from JACC and the JACC specialty journals. We've highlighted the most-cited articles from 2022 for JACC, JACC: Basic to Translational Science, JACC: Cardiovascular Imaging, JACC: Cardiovascular Interventions, JACC: Clinical Electrophysiology, JACC: Cardiology, JACC: Heart Failure, JACC: Asia, and JACC: Case Reports. We've also featured the most talked-about articles in your research community for JACC: Advances.

JACC Journals logo

Journal of the American College of Cardiology

  1. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines(opens in new tab/window)

  2. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines(opens in new tab/window)

  3. 4-Year Outcomes After Left Atrial Appendage Closure Versus Nonwarfarin Oral Anticoagulation for Atrial Fibrillation(opens in new tab/window)

  4. SCAI SHOCK Stage Classification Expert Consensus Update: A Review and Incorporation of Validation Studies: This statement was endorsed by the American College of Cardiology (ACC), American College of Emergency Physicians (ACEP), American Heart Association (AHA), European Society of Cardiology (ESC) Association for Acute Cardiovascular Care (ACVC), International Society for Heart and Lung Transplantation (ISHLT), Society of Critical Care Medicine (SCCM), and Society of Thoracic Surgeons (STS) in December 2021(opens in new tab/window)

  5. Management of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review(opens in new tab/window)

JACC: Basic to Translational Science

  1. Nicotinamide Mononucleotide Alleviates Cardiomyopathy Phenotypes Caused by Short-Chain Enoyl-Coa Hydratase 1 Deficiency(opens in new tab/window)

  2. The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury(opens in new tab/window)

  3. Targeting the Inflammasome in Cardiovascular Disease(opens in new tab/window)

  4. Erythrocytes Induce Vascular Dysfunction in COVID-19(opens in new tab/window)

  5. Optimizing Foundational Therapies in Patients With HFrEF: How Do We Translate These Findings Into Clinical Care?(opens in new tab/window)

JACC: Cardiovascular Imaging

  1. Effect of Evolocumab on Coronary Plaque Phenotype and Burden in Statin-Treated Patients Following Myocardial Infarction(opens in new tab/window)

  2. Clinical Importance of Left Atrial Infiltration in Cardiac Transthyretin Amyloidosis(opens in new tab/window)

  3. Cardiovascular Magnetic Resonance for Patients With COVID-19(opens in new tab/window)

  4. Clinical Deployment of Explainable Artificial Intelligence of SPECT for Diagnosis of Coronary Artery Disease(opens in new tab/window)

  5. Association of Regional Wall Shear Stress and Progressive Ascending Aorta Dilation in Bicuspid Aortic Valve(opens in new tab/window)

JACC: Cardiovascular Interventions

  1. Distal or Traditional Transradial Access Site for Coronary Procedures: A Single-Center, Randomized Study(opens in new tab/window)

  2. Short Duration of DAPT Versus De-Escalation After Percutaneous Coronary Intervention for Acute Coronary Syndromes(opens in new tab/window)

  3. 1-Year Outcomes of Blinded Physiological Assessment of Residual Ischemia After Successful PCI: DEFINE PCI Trial(opens in new tab/window)

  4. Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial(opens in new tab/window)

  5. Permanent Pacemaker Reduction Using Cusp-Overlapping Projection in TAVR: A Propensity Score Analysis(opens in new tab/window)

JACC: Clinical Electrophysiology

  1. Temporal Changes and Clinical Implications of Delayed Peridevice Leak Following Left Atrial Appendage Closure(opens in new tab/window)

  2. Clinical Impact of Residual Leaks Following Left Atrial Appendage Occlusion: Insights From the NCDR LAAO Registry(opens in new tab/window)

  3. Substrate Modification Using Stereotactic Radioablation to Treat Refractory Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy(opens in new tab/window)

  4. Left Cardiac Sympathetic Denervation for Long QT Syndrome: 50 Years’ Experience Provides Guidance for Management(opens in new tab/window)

  5. His-Purkinje Conduction System Pacing in Atrioventricular Block: New Insights Into Site of Conduction Block(opens in new tab/window)

JACC: Heart Failure

  1. A Systematic Review and Network Meta-Analysis of Pharmacological Treatment of Heart Failure With Reduced Ejection Fraction(opens in new tab/window)

  2. Baseline Characteristics of Patients With HF With Mildly Reduced and Preserved Ejection Fraction: DELIVER Trial(opens in new tab/window)

  3. Renal Compression in Heart Failure: The Renal Tamponade Hypothesis(opens in new tab/window)

  4. Impact of Temporary Percutaneous Mechanical Circulatory Support Before Transplantation in the 2018 Heart Allocation System(opens in new tab/window)

  5. Happy Heart Syndrome: Frequency, Characteristics, and Outcome of Takotsubo Syndrome Triggered by Positive Life Events(opens in new tab/window)

JACC: Case Reports

  1. Pulsed Field Ablation for Persistent Superior Vena Cava: New Solution for an Old Problem(opens in new tab/window)

  2. Successful Closure of Paravalvular Leak Using Computed Tomography Image Fusion and Planning With 3-Dimensional Printing(opens in new tab/window)

  3. Sinus Node Artery Occlusion During Cardiac Denervation Procedures(opens in new tab/window)

  4. Transcatheter Occlusion of Coronary-Pulmonary Fistula With a Liquid Embolic Agent After Evaluation by FFR(opens in new tab/window)

  5. Left Atrial Venoarterial Extracorporeal Membrane Oxygenation for Acute Aortic Regurgitation and Cardiogenic Shock(opens in new tab/window)

JACC: CardioOncology

  1. The Role of Cardioprotection in Cancer Therapy Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review(opens in new tab/window)

  2. Incident Cardiovascular Disease Among Adults With Cancer: A Population-Based Cohort Study(opens in new tab/window)

  3. Cancer Incidence and Mortality According to Pre-Existing Heart Failure in a Community-Based Cohort(opens in new tab/window)

  4. Lifestyle and Cardiovascular Risk Factors Associated With Heart Failure Subtypes in Postmenopausal Breast Cancer Survivors(opens in new tab/window)

  5. Cardiovascular Disease Among Patients With AML and CHIP-Related Mutations(opens in new tab/window)

JACC: Asia

  1. Antithrombotic Therapy After Acute Coronary Syndromes or Percutaneous Coronary Interventions in East Asian Populations(opens in new tab/window)

  2. Effect of the ALDH2 Variant on the Prevalence of Atrial Fibrillation in Habitual Drinkers(opens in new tab/window)

  3. Atrial Fibrillation Better Care Pathway Adherent Care Improves Outcomes in Chinese Patients With Atrial Fibrillation(opens in new tab/window)

  4. Prevalence, Genetic Background, and Clinical Phenotype of Congenital Thrombophilia in Chronic Thromboembolic Pulmonary Hypertension(opens in new tab/window)

  5. Differences in Plaque Characteristics and Myocardial Mass: Implications for Physiological Significance(opens in new tab/window)

JACC: Advances

  1. Geriatric Cardiology: Coming of Age(opens in new tab/window)

  2. Born to age: when adult congenital heart disease converges with geroscience(opens in new tab/window)

  3. Medical education in the digital era: A new paradigm for acquiring knowledge and building communities (opens in new tab/window)

  4. Current-Era outcomes of balloon aortic valvotomy in neonates and infants(opens in new tab/window)

  5. Augmented Intelligence to Identify Patients With Advanced Heart Failure in an Integrated Health System(opens in new tab/window)