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The Impact of Nutrition and Statins on Cardiovascular Diseases - 1st Edition - ISBN: 9780128137925, 9780128137932

The Impact of Nutrition and Statins on Cardiovascular Diseases

1st Edition

Authors: Ioannis Zabetakis Ronan Lordan Alexandros Tsoupras
Paperback ISBN: 9780128137925
eBook ISBN: 9780128137932
Imprint: Academic Press
Published Date: 15th January 2019
Page Count: 348
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The Impact of Nutrition and Statins on Cardiovascular Diseases presents a summary of the background information and published research on the role of food in inhibiting the development of cardiovascular diseases. Written from a food science, food chemistry, and food biochemistry perspective, the book provides insights on the origin of cardiovascular diseases, an analysis of statin therapy, their side effects, and the role of dietary intervention as an alternative solution to preventing cardiovascular diseases. It focuses on the efficacy of nutrition and statins to address inflammation and inhibit the onset of disease, while also providing nutrition information and suggested dietary interventions.

Key Features

  • Includes a bioscience approach that focuses on inflammation and revisits the lipid hypothesis
  • Presents the view that nutritional interventions have considerable value, not only for reducing cardiovascular risk for CVDs patients, but also acting as the best precaution for otherwise healthy people
  • Advocates that nutritional habits that are formed at a young age are the best way to tackle the global epidemic that is CVDs


Nutrition researchers, CVDs and public health researchers, CVDs clinicians, Nutritionists and Dietitians, Students in health related fields, Food Chemists and Food Biochemists (Academic, R+D, industrial), Regulatory bodies

Table of Contents

1. The Origin of Chronic Diseases with Respect to Cardiovascular Disease
Ronan Lordan, Alexandros Tsoupras, and Ioannis Zabetakis
2. Inflammation
Ronan Lordan, Alexandros Tsoupras, and Ioannis Zabetakis
3. Inflammation and Cardiovascular Diseases
Alexandros Tsoupras, Ronan Lordan, and Ioannis Zabetakis
4. The Lipid Hypothesis and The Seven Countries Study
Ronan Lordan, Alexandros Tsoupras, and Ioannis Zabetakis
5. The Role of Cholesterol in Atherosclerosis, CVD, and Dietary Patterns
Alexandros Tsoupras, Ronan Lordan, and Ioannis Zabetakis
6. Statins: Rationale, Mode of Action, and Side-effects
Sherif Sultan, Ashwini D’Souza, Ioannis Zabetakis, Ronan Lordan, Alexandros Tsoupras, Edel P Kavanagh, and Niamh Hynes
7. Cardiovascular Risk: Assumptions, Limitations, and Research
Alexandros Tsoupras, Ronan Lordan, and Ioannis Zabetakis
8. Diet and Cardiovascular Disease: The Mediterranean Diet
Audrey Tierney, Ronan Lordan, Alexandros Tsoupas, and Ioannis Zabetakis
9. Nutrition Versus Statins in Primary Prevention: Where do we Stand Now?
Ioannis Zabetakis, Ronan Lordan, and Alexandros Tsoupras


No. of pages:
© Academic Press 2019
15th January 2019
Academic Press
Paperback ISBN:
eBook ISBN:

About the Authors

Ioannis Zabetakis

Ioannis Zabetakis has studied and worked in Greece, United Kingdom and Ireland. Originally a chemist, he fell in love with food science (sensory and functional properties of food). After an academic career at the Universities of Leeds and Athens spanning 15 years, where he developed a strong interest in lipids and cardiovascular diseases, Ioannis joined the Department of Biological Sciences at the University of Limerick (UL) in Ireland. In UL, the ongoing focus of his work is on the cardioprotective properties of food lipids with a particular emphasis on dairy and marine foods. With >75 papers and two patents, his quest is toward a healthier diet and lifestyle that will render us less dependent on medicines. Twitter Handle: @yanzabet

Affiliations and Expertise

Lecturer and Course Leader, Biological Sciences, Department of Biological Sciences, University of Limerick, Limerick, Ireland

Ronan Lordan

Ronan Lordan carried out his undergraduate studies at the University of Limerick, graduating with a first-class honors Bachelor of Science degree in Biological Sciences and Education in 2015. Ronan taught Leaving Certificate Biology and Chemistry in Irish second-level schools before returning to the University of Limerick in 2016 to begin his PhD scholarship to study the role of dietary polar lipids in inflammation and cardiovascular disease. Ronan has lectured on various topics including lipids chemistry, genetics, and health. Ronan has published several peer-reviewed papers. His research interests include: (a) elucidating the structures of bioactive polar lipids in various foods; (b) developing novel functional foods and nutraceuticals against cardiovascular disease; and (c) discerning the mechanisms of platelet-activating factor-induced systemic inflammation. Ronan is the process of completing his PhD. Twitter Handle: @el_ronan

Affiliations and Expertise

Biological Sciences, Department of Biological Sciences, University of Limerick, Limerick, Ireland

Alexandros Tsoupras

Alexandros Tsoupras has studied (BSc, MSc, PhD) and worked as a chemist and biochemist since 2002 in several academic and research institutions in Greece, the United States, and Ireland (i.e., the University of Athens, the Technological Educational Institute of Athens, the Directorate of the Environment of the Region of Attica, Albany Medical College, the University of Limerick, etc.). He has participated in research regarding the implication of inflammation on several chronic disorders, such as CVD, cancer, renal disorders, chronic infections, etc. His main interests concern not only the beneficial pleiotropic effects and side effects of several drugs, such as statins, antibiotics, antiretrovirals, etc., but also the beneficial effects of nutraceuticals, food supplements, and bioactive microconstituents of natural origin, such as those derived from healthy foods, microorganisms of biotechnological interest, and several medicinal plants, on inflammatory disorders. Alexandros’ beliefs lie on appropriately using and improvising the existing naturally derived “weapons” of a healthy dietary pattern and lifestyle toward the prevention of chronic disorders to improve our quality of life. His motto is "As long as we have the opportunity, let us do our best for the good of all in the short time given to us". Twitter Handle: @bioflips

Affiliations and Expertise

Chemist-Biochemist, Department of Biological Sciences, School of Natural Sciences, Faculty of Sciences and Engineering, Limerick, Ireland


"Low-level inflammation is the core underlying cause of most illness and disease. This evidence-based book shines a ground-breaking light on inflammation’s negative effect with regard to heart disease and the use of statins. This is a book that all health practitioners should have on their shelves." --Lori Shemek, PhD, CNC, bestselling author of ‘How to Fight FATflammation’

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