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Lignin-based Materials for Biomedical Applications - 1st Edition - ISBN: 9780128203033, 9780128203040

Lignin-based Materials for Biomedical Applications

1st Edition

Preparation, Characterization, and Implementation

Editors: Patrícia Figueiredo Hélder Santos
Paperback ISBN: 9780128203033
eBook ISBN: 9780128203040
Imprint: Elsevier
Published Date: 26th July 2021
Page Count: 448
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Lignin-based Materials for Biomedical Applications: Preparation, Characterization, and Implementation explores the emerging area of lignin-based materials as a platform for advanced biomedical applications, guiding the reader from source through to implementation.

The first part of the book introduces the basics of lignin, including extraction methods, chemical modifications, structure and composition, and properties that make lignin suitable for biomedical applications. In addition, structural characterization techniques are described in detail. The next chapters focus on the preparation of lignin-based materials for biomedical applications, presenting methodologies for lignin-based nanoparticles, hydrogels, aerogels, and nanofibers, and providing in-depth coverage of lignin-based materials with specific properties—including antioxidant properties, UV absorbing capability, antimicrobial properties, and colloidal particles with tailored properties—and applications, such as drug and gene delivery, and tissue engineering. Finally, future perspectives and possible new applications are considered.

This is an essential reference for all those with an interest in lignin-based materials and their biomedical applications, including researchers and advanced students across bio-based polymers, polymer science, polymer chemistry, biomaterials, nanotechnology, materials science and engineering, drug delivery, and biomedical engineering, as well as industrial R&D and scientists involved with bio-based polymers, specifically for biomedical applications.

Key Features

  • Unlocks the potential of lignin-based materials with advanced properties for cutting-edge applications in areas such as drug delivery, gene delivery and tissue engineering
  • Presents state-of-the-art methodologies used in the development of lignin-based nanoparticles, hydrogels, aerogels and nanofibers
  • Explains the fundamentals of lignin, including structure and composition, extraction and isolation methods, types and properties, chemical modifications, and characterization techniques


Academia: Researchers and advanced students across bio-based polymers, polymer science, polymer chemistry, biomaterials, nanotechnology, materials science and engineering, drug delivery, biomedical engineering. Industry: Scientists and R&D with an interest in bio-based polymers, specifically for biomedical applications.

Table of Contents

1 Introduction to lignocellulosic materials
2 Lignin: an innovative, complex, and highly flexible plant
3 Lignin extraction and isolation methods
4 Types of lignin, properties, and structural
characterization techniques
5 Chemical modifications of lignin
6 Requirements and properties of biomaterials for
biomedical applications
7 Development of lignin-based nanoparticles: fabrication
methods and functionalization approaches
8 Lignin-based materials with UV-blocking property
9 Lignin-based materials with antioxidant and
antimicrobial properties
10 Lignin-based materials for drug and gene delivery
11 Fabrication of lignin-based hydrogels and their
12 Present and future prospective of lignin-based materials
in biomedical fields


No. of pages:
© Elsevier 2021
26th July 2021
Paperback ISBN:
eBook ISBN:

About the Editors

Patrícia Figueiredo

Patrícia Figueiredo is a postdoctoral researcher at the University of Helsinki, where she obtained her PhD in Pharmaceutical Technology with honors in 2020. Her research is focused on the development of lignin-based nanosystems with potential application in biomedicine and food science. She has authored/co-authored 37 publications, including reviews and book chapters, and 6 oral/poster presentations in international scientific meetings. She also has more than 800 citations and h-index=14.

Affiliations and Expertise

Division of Pharmaceutical Chemistry and Technology, University of Helsinki, Finland

Hélder Santos

Hélder A. Santos is a Full Professor in Pharmaceutical Nanotechnology at the Faculty of Pharmacy of the University of Helsinki (Finland), Head of the Nanomedicines and Biomedical Engineering Lab, Director of the Doctoral Program in Drug Research, Director of FinPharmaNet in Finland, Chair of the Controlled Release Society Focus Group in Nanomedicine and Nanoscale Delivery, and Chairman and co-founder of Capsamedix Oy. Prof. Santos’ research is focused on nanobiomaterials, including nanoporous silica/silicon materials and polymeric-based nanoparticles for controlled drug delivery, diagnostics, and therapy. His research interests include the development of nanoparticles/nanomedicines for biomedical and healthcare applications. His current work builds a bridge between engineering, pharmaceutical, and medical research. He is the author/co-author of more than 330 publications, including reviews, journal editorials, book chapters, 4 edited books, and more than 260 conference proceedings/abstracts. He also holds 4 patents in the field.

Affiliations and Expertise

Full Professor, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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