Essentials of Medical Biochemistry

Essentials of Medical Biochemistry

With Clinical Cases

3rd Edition - August 1, 2022

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  • Authors: Chung-Eun Ha, N. V. Bhagavan
  • Paperback ISBN: 9780323885416

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Essentials of Medical Biochemistry, Third Edition offers a condensed, yet detailed overview of clinical biochemistry, spanning fundamentals and relevant physiologic and pathophysiologic concepts. Pivotal clinical case studies aid in understanding basic science in the context of diagnosis and treatment of human diseases, and the text illuminates key topics in molecular immunology and hemostasis. Users will find fundamental concepts aiding students and professionals in biochemistry, medicine, and other healthcare disciplines. The text is a useful refresher that will help users meet USMLE and other professional licensing examination requirements, providing thorough introductions, key points, multicolored illustrations of chemical structures and figures, fact-filled tables, and recommended reading lists. This Third Edition has been fully updated to address evolving techniques in the biological sciences, including genomics, metabolomics, transcriptomics, epigenomics, proteomics, and gene therapy, among other methods. In addition, each chapter has been fully revised for current science and now features learning objectives and chapter summaries, supplemental reading, and 5 clinical case based multiple choice questions. New clinical cases have been added throughout.

Key Features

  • Integrates the biochemical principles with physiological, pharmacological, and pathological aspects of human diseases
  • Each chapter features learning objectives, summaries, required and supplemental reading lists, clinical cases, and multiple-choice questions
  • Presents essential biochemical concepts within the context of their biological functions Offers instructional overview figures, flowcharts, tables and multi-colored illustrations
  • Provides an online ancillary package with PowerPoint images and an additional 500 study questions to aid in comprehension and USMLE exam preparation


Medical students, dentistry students, pharmaceutical students, and graduate students in medical biochemistry; Active researchers in biochemistry, molecular biology, pharmaceutical science, and cellular biology; medical chemists; Clinicians

Table of Contents

  • 1. The Human Organism: Organ Systems, Cells, Organelles, and Our Microbiota
    2. Water, Acids, Bases, and Buffers
    3. Amino Acids
    4. Three-Dimensional Structure of Proteins and Disorders of Protein Misfolding
    5. Energetics of Biological Systems, Enzymes and Enzyme Regulation
    6. Clinical Enzymology and Biomarkers of Tissue Injury
    7. Simple Carbohydrates
    8. Heteropolysaccharides: Glycoconjugates, Glycoproteins, and Glycolipids
    9. Connective Tissue: Fibrous and Nonfibrous Proteins and Proteoglycans
    10. Gastrointestinal Digestion and Absorption
    11. Carbohydrate Metabolism I: Glycolysis and the Tricarboxylic Acid Cycle
    12. Electron Transport Chain, Oxidative Phosphorylation, and Other Oxygen-Consuming Systems
    13. Carbohydrate Metabolism II: Gluconeogenesis, Glycogen Synthesis and Breakdown, and Alternative Pathways
    14. Protein and Amino Acid Metabolism
    15. Lipids I: Fatty Acids and Eicosanoids
    16. Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
    17. Lipids III: Plasma Lipoproteins
    18. Contractile Systems
    19. Perturbations of Energy Metabolism: Obesity and Diabetes Mellitus
    20. Structure and Properties of DNA
    21. DNA Replication, Repair, and Mutagenesis
    22. RNA and Protein Synthesis
    23. Regulation of Gene Expression
    24. Nucleotide Metabolism
    25. Hemoglobin and Metabolism of Iron & Heme
    26. Endocrine Metabolism I: Introduction and Signal Transduction
    27. Endocrine Metabolism II: Hypothalamus and Pituitary
    28. Endocrine Metabolism III: Adrenal Glands
    29. Endocrine Metabolism IV: Thyroid Gland
    30. Endocrine Metabolism V: Reproductive System
    31. Immunology
    32. Biochemistry of Hemostasis
    33. Mineral Metabolism
    34. Vitamin Metabolism
    35. Drug Metabolism

Product details

  • No. of pages: 840
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: August 1, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780323885416

About the Authors

Chung-Eun Ha

Chung-Eun Ha
Chung-Eun Ha is an Associate Professor in the department of Native Hawaiian Health

at the John A. Burns School of Medicine, University of Hawaii at Manoa. Since 2001,

he has been teaching medical biochemistry to students who come from disadvantaged

backgrounds. He is also actively involved in the various aspects of molecular biology

and biochemical research in the field of clinical medicine.

Affiliations and Expertise

Associate Professor, Department of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA

N. V. Bhagavan

N. V. Bhagavan
N. V. Bhagavan is an Emeritus Professor in the department of Anatomy, Biochemistry,

and Physiology at the John A. Burns School of Medicine, University of Hawaii at Manoa.

An active professor, researcher, and teacher, he has many years of experience in both

the instruction and practice of clinical biochemistry.

Affiliations and Expertise

Emeritus Professor, Department of Anatomy, Biochemistry, and Physiology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA

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