Engineering of Biomaterials for Drug Delivery Systems

Engineering of Biomaterials for Drug Delivery Systems

Beyond Polyethylene Glycol

1st Edition - January 27, 2018

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  • Editor: Anilkumar Parambath
  • Hardcover ISBN: 9780081017500
  • eBook ISBN: 9780081017517

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Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field.

Key Features

  • Provides a self-contained work for the field of biomaterials for drug delivery
  • Summarizes the current knowledge on PEGylation and strategies for bypassing it
  • Presents research on an important, though under-represented issue in biomaterials
  • Written by a world-class team of research scientists, engineers and clinicians


Researchers and scientists in biomaterials for drug delivery, biomaterials synthesis, pharmaceuticals and nanotechnology

Table of Contents

  • 1. PEGylated ‘stealth’ liposomes
    2. PEGylated proteins
    3. PEGylation and anti-PEG antibodies
    4. Poly (zwitterions)
    5. Poly (glycerols)
    6. Poly (oxazolines)
    7. Poly (aminoacids)
    8. Poly (acylamides) and related systems
    9. Poly (vinylpyrrolidones)
    10. Sugar based systems (trehalose)
    11. Polypeptide alternatives (PASylation and XTen) to PEG
    12. DDS based on non-immunogenic biopolymers
    13. Non-PEGylated nanoparticles
    14. Summary and future perspectives

Product details

  • No. of pages: 404
  • Language: English
  • Copyright: © Woodhead Publishing 2018
  • Published: January 27, 2018
  • Imprint: Woodhead Publishing
  • Hardcover ISBN: 9780081017500
  • eBook ISBN: 9780081017517

About the Editor

Anilkumar Parambath

Dr Anilkumar Parambath is Senior Manager and Head of Capsules Product R&D, ACG Capsules, Mumbai, India. Prior to this he was a Principal Investigator for Performance and Specialty Materials at Syngene International Ltd, Bangalore India, where he worked on developing various elastomers, silicones, acrylics and other polymers for biomedical applications. He completed his PhD in Chemistry (Polymer Science) at the University of Kerala, India, and spend 7 years conducting post-doctoral research at Clemson University, USA, French atomic Energy Commission (CEA), France, and the University of British Columbia, Canada. He has successfully led RnD programs of several innovation initiatives in academic and industry settings. Dr. Parambath has edited two books on polymer biomaterials in drug delivery applications, including one with Elsevier in the Woodhead Publishing in Biomaterials series, and has published many books chapters and journal articles. He has two patents to his name.

Affiliations and Expertise

Syngene International Ltd, Bangalore, India

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