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Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracell… Read more
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Immediately download your ebook while waiting for your print delivery. No promo code is needed.
Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78.
Cell biology researchers, teachers and graduate students specializing in the areas of medical oncology, lipidology, pharmacology and drug development, protein chemistry/biochemistry, infectious diseases, neurology and hematology. The book may be of interest also to members of pharmaceutical companies
1. Introduction to the Discovery of the Endoplasmic Reticulum Chaperone GRP78 on the Cell Surface
2. The Endoplasmic Reticulum Chaperone GRP78 also Functions as a Cell Surface Signaling Receptor
3. Cell surface GRP78: Anchoring and Translocation Mechanisms and Therapeutic Potential in Cancer
4. Cell Surface GRP78: A Targetable Marker of Cancer Stem-like Cells
5. Cell Surface GRP78 Regulates the Pro-Coagulant Activity of Tissue Factor
6. GRP78 Modulates the Plasminogen Activating System in the Brain: Implications for Human Disease
7. Escherichia coli Subtilase Cleaves Cell Surface GRP78 preventing COOH-terminal Signaling
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