Animal Biotechnology - 2nd Edition - ISBN: 9780128117101, 9780128117255

Animal Biotechnology

2nd Edition

Models in Discovery and Translation

Editors: Ashish Verma Anchal Singh
eBook ISBN: 9780128117255
Hardcover ISBN: 9780128117101
Imprint: Academic Press
Published Date: 1st September 2018
Page Count: 784
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The development of new genomic and molecular tools and their translational potential for human health has resulted in rapid advances in animal biotechnology, making it an essential knowledge area for those conducting translational biomedical research. Animal Biotechnology: Models in Discovery and Translation, Second Edition provides a helpful guide to all students and individuals who are new to the field or seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, as well as in-depth examples of implications for human health and prospects for the future. Fully revised and all-new chapters speak to animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, cancer, HPV, HIV, and aging.

Key Features

  • Highlights latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases
  • Offers first-hand accounts of the use of biotechnology tools including molecular markers, stem cells, animal cultures, tissue engineering, ADME, and CAM Assay
  • Includes case studies which illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies
  • Provides a helpful guide to all students and researchers who are new to the field or those seeking a thorough introduction to animal biotechnology applications and their translational potential
  • This fully revised, all-new edition speaks to various disease types and methods, including animal biotechnology as applied to in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, cancer, HPV, HIV, and aging


Students and researchers of biotechnology, animal biotechnology, genetics, genomics, genomic medicine, molecular medicine, oncology, stem cell research, regenerative medicine, pharmacology, and immunology

Table of Contents

Section I: Human Diseases: In Vivo and In Vitro Models

1. Drosophila: A Model for Biotechnologist

2. Animal Models of Tuberculosis

3. Animal Model for Neurodegenerative Disorders

4. Epigenetics and Animal Models: Applications in Cancer Control and Treatment

5. Development of Mouse Models for Cancer Research

6. Human Papillomavirus (HPV): Diagnosis and Treatment

7. Human DNA Tumor Viruses and Oncogenesis

8. Animal Models for Human Disease

9. HIV and Antiretroviral Drugs

10. Animal Biotechnology as a Tool to understand and Fight Aging

Section II: Animal Biotechnology: Tools and Techniques

11. MultiCellular Spheroid: 3-D tissue Culture Model for Cancer Research

12. Animal Tissue Culture: Principles and Applications

13. Concepts of Tissue Engineering

14. Nanotechnology and Its Applications to Animal Biotechnology

15. Antibodies: Monoclonal and Polyclonal

16. Molecular Markers: Tool for Genetic Analysis

17. Gene Expression: Analysis and Quantitation

18. Ribotyping: A Tool for Molecular Taxonomy

19. Next Generation Sequencing and Its Applications

20. Biomolecular Display Technology: A New Tool for Drug Discovery

21. In Silico Model: From Simple Networks to Complex Diseases

Section III: Animal Biotechnology: Applications and Concerns

22. Transgenic Animals and their Applications

23. Stem Cells: A Trek from Laboratory to Clinic to Industry

24. Role of Cytogenetic and Molecular Genetics in Human Health and Medicine

25. Antibodies and their Applications

26. Vaccines: Present Status and Applications

27. Safety Assessment of Food Derived from Genetically Modified Crops

28. Nanotechnology and Detection of Microbial Pathogens

29. Biotechnological Exploitation of Marine Animals

30. Herbal Medicine and Biotechnology for the Benefit of Human Health

31. Ethical Issues in Animal Biotechnology

32. CAM Assay

33. In vitro Fertilization

34. Human Embryonic Stem Cells

35. Biosensor

36. Animal Cloning

37. Animal Models for Enteric Diseases

38. Biosafety

39. Animal Experimentation: Issues and Non-Issues

40. Biopharming

41. Organ Transplantation

42. Enzyme inhibition assay for metabolic disorders - exploring leads from medicinal plants

43. Intellectual Property Right and Animal Biotechnology


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About the Editor

Ashish Verma

He has published more than thirty articles in peer reviewed journals, co-edited five books, and authored five individual book chapters. Dr. Verma serves as Associate Editor of the Journal of Agricultural and Biological Research, Research Journal of Immunology, International Journal of Virology, Journal of Pharmacology and Toxicology, Journal of Pharmacy and Bioallied Sciences and Advances in Integrative Omics and Applied Biotechnology. He also serves as Chief Editor of Biolixer and is a full member of the Indian Immunology Society, the Association of Microbiologists of India, the Society of Biological Chemists, the Society of Toxicology, the Indian Science Congress, and the Biotechnology Society of India. Dr. Ashish has been an invited guest speaker at numerous international scientific meetings, chaired ten scientific meetings in India and abroad, and received research grants and awards from the Indian Ministry of Education, the Council of Scientific and Industrial Research, the International Union of Immunology, the Weizmann Institute of Science, and the Catholic University of Rome among other organizations.

Affiliations and Expertise

Professor and Pro-Vice-Chancellor, Jadavpur University, Kolkatta, India and formerly Professor, Amity Institute of Biotechnology, Amity University, Uttar Pradesh, India

Anchal Singh

Dr. Singh teaches biochemistry and immunology to post graduate students at Baranas Hindu University and her research interests and areas of expertise include parasite immunology, immunodiagnostics, animal cell cultures, in vitro assays, and antibiotic resistance in bacteria. Her research has been funded by the Indian Department of Science and Technology and the Indian Department of Biotechnology. She has co-edited five books, authored articles for peer reviewed journals, and authored nine individual book chapters in her various research areas. Additionally, Dr. Singh is a full member of the Association of Microbiologists of India, the Society of Biological Chemists, and AIDSCON and has served as Treasurer of “National Symposium on HIV and AIDS: Biology to Bedside” held at Amity University (2012), the “International Symposium on Frontiers in Cancer Research: Prevention to Therapeutics” at Amity University (2013), and the “26th National Congress of Parasitology” held at Banaras Hindu University (2016).

Affiliations and Expertise

Assistant Professor, Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, India and formerly Assistant Professor, Amity University, Uttar Pradesh, India

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