Books in Toxicology

441-450 of 460 results in All results

Pharmacology of Cardiac Function

1st Edition
January 1, 1964
Otto Krayer
English
eBook
9 7 8 - 1 - 4 8 3 1 - 6 4 5 2 - 6

Pharmacology of Cardiac Function brings together the proceedings of the Second International Pharmacological Meeting of the International Union of Physiological Sciences, held in Prague, Czechoslovakia, on August 20-23, 1963. The meeting provided a forum for discussing advances in the understanding of the pharmacology of cardiac function and addressed topics ranging from the link between muscle physiology and the heart to the development of tension in cardiac muscle. This volume is comprised of 21 chapters and begins with an overview of the structural aspects of contraction in cardiac and skeletal muscle, followed by a description of muscle physiology and its effect on the heart. The next section deals with the effects of drugs on the interval-strength relationship of heart muscle, paying particular attention to acetylstrophanthidin, levarterenol, and carbacliol as well as metabolic inhibitors. The nature of the restitution process occurring between beats in cardiac muscle is also considered. Subsequent chapters explore how the heart is affected by the action of the vagus and of acetylcholine and other parasympathomimetic drugs; membrane effects of epinephrine and digitalis; and the mode of action of antifibrillatory drugs. This book will be of particular value to pharmacologists and physiologists.

Insecticides

1st Edition
January 1, 1964
Gunter Zweig
English
eBook
9 7 8 - 1 - 4 8 3 2 - 2 1 7 7 - 9

Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume II: Insecticides contains detailed analytical procedures for analysis of 47 widely used insecticides. This volume is composed of 47 chapters that cover the history, biological and chemical properties, and physical constants of these insecticides. Each chapter presents first the general information, followed by intensive discussion of the methods of occurrence and residue analysis of the insecticide. Methods of analysis covered in each chapter include chemical methods, gas-liquid chromatography, colorimetry, and enzymatic techniques. Each chapter also provides analysis of phosphorus and acetylcholinesterase inhibition of the insecticide, which is classified into two groups, namely, organochlorine and organophosphorus. Agriculturists, analytical chemists, and toxicologists will find this book rewarding.

Drugs in Cerebral Palsy

1st Edition
January 1, 1964
Eric Denhoff + 2 more
Eric Denhoff
English
eBook
9 7 8 - 1 - 4 8 3 2 - 2 1 8 4 - 7

Clinics in Developmental Medicine No. 16: Drugs in Cerebral Palsy: Based on a Symposium held at Dallas, 24-26 November, 1963 is a collection of papers of the 1963 Symposium on Drugs in Cerebral Palsy, arranged by the American Academy. This book is composed of nine chapters that cover the various components and treatment options involved in cerebral palsy. This text begins with a presentation of the many problems of drug evaluation, with an emphasis on the issue that human responses to a drug cannot be predicted from those of animals and that the response of one human to a drug may differ quite sharply from that of another. The next chapters deal with the historical developments and pharmacology of drugs in cerebral palsy, as well as the two aspects of drug evaluation, namely, the immediate or direct effects of the drug on patients and the double-blind test. The discussion the shifts to the pharmacological capacity of muscle relaxants and anti-convulsant drugs. The last chapter considers the possible toxic drug reactions, which are the result of individual idiosyncrasy and may occur regardless of drug dosage. This book will be of value to pharmacologists, neurologists, clinicians, and researchers who are interested in drug evaluation in cerebral palsy.

Evaluation of Drug Activities

1st Edition
January 1, 1964
D R Laurence + 1 more
English
eBook
9 7 8 - 1 - 4 8 3 2 - 6 3 4 6 - 5

Evaluation of Drug Activities: Pharmacometrics, Volume 1 provides a review and critical discussion of general and special pharmacological methods used in the search of new drugs. This book discusses the fundamental difference between a pharmacological study and a bio-assay in the nature of the biological activity. Organized into two parts encompassing 19 chapters, this book begins with an overview of the pharmacological and toxicological studies on animals. This text then discusses the method of producing clinically successful drugs. Other chapters consider the objective of toxicity testing in determining the complications arising from the pharmacological action of the drug and also in discovering any unexpected side-effects. This book discusses as well the pharmacological effects and heredity in laboratory animals. The final chapter deals with the various aspects of hypertensive disease and its treatment. This book is a valuable resource for scientists, biologists, physiologists, pharmacologists, biochemists, physicians, clinicians, and research workers.

Evaluation of Drug Activities

1st Edition
January 1, 1964
D R Laurence + 1 more
English
eBook
9 7 8 - 1 - 4 8 3 2 - 6 2 8 4 - 0

Evaluation of Drug Activities: Pharmacometrics, Volume 2 provides information pertinent to the fundamental aspects of pharmacometrics. This book covers a variety of topics, including anticholinesterases, antitussives, cardioactive agents, diuretics, dermatological agents, and estrogens. Organized into 21 chapters, this volume begins with an overview of anticholinesterases and its pharmacological and physiological actions. This text then examines the diversity of methods for evaluating antitussive drugs, which is related to the complexity of cough reflexes. Other chapters consider tests for cardioactive substances of three general classes, namely, the cardiac glycosides, the coronary vasodilators, and the anti-arrhythmics. This book discusses as well the introduction of many diuretics into therapeutic practice during the past years bears witness to the convenience and success of the tests available for assessing drugs of this class. The final chapter deals with drugs affecting lipid levels in plasma. This book is a valuable resource for chemists, physiologists, pharmacologists, and clinicians.

Symptomatology and Therapy of Toxicological Emergencies

1st Edition
January 1, 1964
William B. Deichmann + 1 more
English
eBook
9 7 8 - 1 - 4 8 3 2 - 7 4 4 9 - 2

Symptomatology and Therapy of Toxicological Emergencies is a handbook on toxicological emergencies that includes much new material and discusses many new substances which have become available since the second edition, entitled ""Signs, Symptoms, and Treatment of Certain Acute Intoxications,"" was published in 1958. When compared with the second edition, this volume covers a considerably larger number of drugs and chemicals, presents urgently needed information on poisonous plants, lists the compounds implicated in blood dyscrasias, and includes accepted threshold limit values for chemicals, the maximum permissible concentrations of various chemicals in food, drugs, and cosmetics, as well as tables on the acute toxicity of numerous chemicals. This handbook will be helpful to teachers of chemistry, biochemistry, pharmacology, toxicology, radiation medicine, etc., who instruct students or supervise the work of technicians. It will be of particular value to those industries and operations which have an active industrial hygiene program. Finally, but most important, this volume was written for the physician who needs toxicological information on a drug or a chemical, who may need a reference book which will quickly review for him the major side effects he may expect in a patient, or who requires additional information for the treatment of an intoxication.

Progress in Chemical Toxicology

1st Edition
January 1, 1963
Abraham Stolman
English
eBook
9 7 8 - 1 - 4 8 3 2 - 1 9 2 2 - 6

Progress in Chemical Toxicology, Volume 1 covers the developments in toxicology, including the usefulness of the developed techniques and methods with necessary modifications for toxicological studies. The book describes the isolation and separation techniques for the identification of poisons; the application of gas chromatograph to toxicology; and the pharmacological and toxicological effects aliphatic alcohols. The text also discusses the isolation, purification, identication, and the toxicology of acidic and neutral poisons, ataraxics and nonbarbiturate sedatives. The determination of antiarthritics, antihistamines, and thymoleptics; the physicochemical properties for the identification of narcotics and related bases; and the toxicity of air pollutants are also considered. The book further tackles the analytical methods for air pollutants; the occurrence, symptoms, and treatment of mushroom poisoning; and the toxic components of poisonous seeds and fruits poisonous seeds and fruits. Toxicologists, chemists, and scientists in forensic science laboratories will find the text invaluable.

Principles, Methods, and General Applications

1st Edition
January 1, 1963
Gunter Zweig
English
eBook
9 7 8 - 1 - 4 8 3 2 - 2 0 8 1 - 9

Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume 1: Principles, Methods, and General Applications provides information on analytical techniques useful for the determination of pesticides, plant growth regulators, and food additives. The book discusses the potential hazard of minute residues to human and animal health; the principles of formulation and residue analyses; and the principles of food additive analysis. The text also describes the extraction and clean-up procedures; and the principles of toxicological testing methods. The methods for pesticide analysis in meat products; and the formulation and residue analysis in government laboratories are also considered. The book further tackles other methods, such as spectrophotometric methods, chromatography, isotope methods, enzymatic methods; and bioassay. Agricultural toxicologists and people studying pesticides and food additives will find the text invaluable.

Experiments with Drugs

1st Edition
January 1, 1963
H. J. Eysenck
English
eBook
9 7 8 - 1 - 4 8 3 2 - 2 3 7 4 - 2

Experiments With Drugs: Studies in the Relation between Personality, Learning Theory and Drug Action provides a report of a series of experiments, conducted to test the effects of certain groups of drugs, depressants and stimulants, on human behavior. The book presents a number of experiments, together with the theoretical rationale underlying their development. The text begins with a chapter that sets the stage for the exposition of the various concepts and findings on drug effects on behavior. Subsequent chapters deal with particular subjects such as personality and drug effects; the effects of stimulant and depressant drugs on visual and auditory masking; excitation-inhibition and the theory of neurosis; interaction effects of drugs; and the influence of stimulant and depressant drugs on the central nervous system. Psychologists, biochemists, and researchers in the field of psychopharmacology will find the book useful and incisive.

The Nervous System

1st Edition
January 1, 1963
Walter S. Root + 1 more
English
eBook
9 7 8 - 1 - 4 8 3 2 - 7 5 8 2 - 6

Physiological Pharmacology: A Comprehensive Treatise, Volume I: The Nervous System — Part A, Central Nervous System Drugs focuses on the influence of drugs on the functions of the central nervous system. The selection first offers information on absorption, distribution, and elimination and effects upon physiological systems. Discussions focus on factors that disturb normal sequence of uptake and elimination of volatile drugs; variations in distribution due to systemic effects of anesthetics; factors influencing the uptake of gases by tissues; and theories of general anesthesia. The book also ponders on alcohols, including alcohols acting on the central nervous system; effect of alcohols on and outside the central nervous system; and synergisms and antagonisms between alcohols and other drugs. The publication takes a look at sedatives and hypnotics, effects upon physiological systems, and analgesics and antipyretic drugs. The text also examines non-narcotic analgesics, tranquilizers, and diphenylmethane derivatives. The selection is a vital source of data for readers interested in the effects of drugs on the central nervous system.