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Books in Toxicology

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Additional Principles and Methods of Analysis

  • 1st Edition
  • January 1, 1967
  • Gunter Zweig
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 2 0 8 2 - 6
Analytical Methods for Pesticides, Plant Growth Regulators, and Food Additives, Volume V: Additional Principles and Methods of Analysis covers the major advances in the analytical techniques used for the qualitative and quantitative determinations of minute amounts of pesticide and plant growth regulator residues in foods and crops. The book discusses developments in analytical methods (i.e. the polarographic technique, thin-layer chromatography) and their general applications; the analytical aspects of pesticide residue analyses in the environment; and specific analytical methods for formulation and residue analyses of insecticides, fungicides, herbicides and plant growth regulators. Agriculturists, agricultural engineers, toxicologists, and people involved in the study of pesticides and biochemicals will find the book invaluable.

Heredity and Environment in the Functional Psychoses

  • 1st Edition
  • January 1, 1967
  • Einar Kringlen
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 9 5 7 8 - 0
Heredity and Environment in the Functional Psychoses involves an epidemiological clinical study of twins carried out at the University Psychiatric Institute in Oslo. The author reviews the history and nosological aspects of psychiatry. In his study of twin genetics, the author seeks to answer the questions "What is inherited?" and "How is it inherited?" In his review of 342 pairs of twins in the Central Register of Psychosis, his study had the following aims: to obtain true concordance figures for all types of functional psychoses; to study problems pertaining to nosology; and to study a larger sample of discordant pairs in order to clarify crucial environmental factors. His findings show that concordance figures for schizophrenia are 25-38 per cent in monozygotic twins and 4-10 per cent ion dizygotic twins. He points out that the difference in such concordance rates between the two types of twins is statistically significant. The data supports the (weak) assumption of a genetic factor in the etiology of schizophrenia. Behavioral scientists, psychiatrists, child psychologists, and researchers involved in genetics will find this book helpful and informative.

Antibiotics

  • 1st Edition
  • January 1, 1967
  • Tadeusz Korzybski + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 2 3 0 4 - 9
Antibiotics; Origin, Nature and Properties, Volume II focuses on the principles of the classification of antibiotic substances. This volume is divided into four main topics—antibiotics produced by Fungi imperfecti, antibiotics produced by fungi belonging to the basidiomycetes and ascomycetes, antibiotics produced by lichens and algae, and antibiotics from higher plants. The antibiotics covered in this book include penicillin, viridicatin, cyclopaldic acid, cephalosporin P, bongkrek acid, chlamydosporine, and flammulin. The diploicin, chlorellin, chlorophorin, ethyl gallate, anacardic acid, and echinacosid are also described. Other antibiotics include the tuberosine, antifungal substance from field corn, fulvoplumerin, plumericin, and chinoc acid. This publication is recommended for pharmacists and specialists interested in the classification of antibiotics.

Antibiotics

  • 1st Edition
  • January 1, 1967
  • Tadeusz Korzybski + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 2 3 0 5 - 6
Antibiotics: Origin, Nature and Properties, Volume I is a systematic coverage of the sources, varieties, and properties of the antibiotics. This book is organized into two main parts encompassing 13 chapters. This book considers the antibiotics according to their sources. It describes the antibiotics produced by bacteria, Actinomycetes,Fungi imperfecti, Basidiomycetes, algae, lichens and green plants, and those from animal sources. This group of antibiotics includes, streptomycin, the tetracyclines, chloromycetin, the macrolide family of compounds of which erythromycin, magnamycin and spiramycin are members, and the antifungal polyene compounds. The members of each group are arranged according to their chemical and biological similarity. Sections on each antibiotic present complete information, including the name, description of the producing strains, composition of the media, methods of culture, isolation and purification of the antibiotic principle, its physical and chemical properties, antibiotic spectrum, toxicity for laboratory animals, results of treatment of experimental infections, and possible clinical applications. This book is of value to researchers and workers in various medical fields.

Progress in Chemical Toxicology

  • 1st Edition
  • January 1, 1967
  • Abraham Stolman
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 2 4 9 1 - 6
Progress in Chemical Toxicology, Volume 3 explores the developments in methods and instrumentation for toxicological analyses. This book is composed of eight chapters, and begins with a description of the pharmacologic and physiologic effects of aliphatic alcohols. The succeeding chapter deals with the methods of analysis of various volatile poisons, such as halogenated aliphatic compounds, aromatic hydrocarbons, and acid compounds. A chapter focuses on the methods of determination and classic procedures for carbon monoxide analysis in breath and blood. These topics are followed by discussions on the development of spectrochemical methods chemical and radiochemical methods of determination of radionuclides in human bones and tissues; and the toxic effects of combined drug action. The last chapter examines the poison residue occurrence in human tissues. This book is of great value to toxicologists and public health workers and researchers.

The Nervous System

  • 1st Edition
  • January 1, 1967
  • Walter S. Root + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 7 2 9 4 - 8
Physiological Pharmacology: A Comprehensive Treatise, Volume III: The Nervous System — Part C: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including cardiovascular effects and metabolism. The selection first offers information on the cardiovascular effects of choline esters and the effects of choline esters on smooth muscles and secretions. Topics include actions of acetylcholine, physiological role of choline esters, and actions of cholinergic drugs on smooth muscles and secretions. The book also takes a look at the pharmacologic, toxicologic, and therapeutic properties of anticholinesterase agents, including the chemistry and metabolism of anticholinesterase substances and mechanisms of action of anticholinesterase agents and role of cholinesterases. The publication examines muscarinic blocking drugs and ganglion-blocking drugs. Discussions focus on actions on the secretory glands and cardiovascular system; distribution, metabolism, and excretion of atropine; substances that block ganglionic transmission; and cardiovascular effects. The text also elaborates on neuromuscular blocking drugs. The selection is a dependable reference for readers interested in the effects of drugs on the nervous system.

The Nervous System

  • 1st Edition
  • January 1, 1967
  • Walter S. Root + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 7 2 9 5 - 5
Physiological Pharmacology: A Comprehensive Treatise, Volume IV: The Nervous System — Part D: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including how adrenergic drugs affect the heart and systemic circulation, metabolism, and adrenergic compounds. The selection first offers information on the effects of adrenergic drugs on the heart and systemic circulation. Topics include actions of adrenergic drugs, possible drug actions on the heart, epinephrine and arterenol, and other sympathomimetic drugs. The book then examines the effects of adrenergic compounds on pulmonary circulation, including physiologic considerations and general considerations of adrenergic compounds. The manuscript ponders on the effects of adrenergic agents on smooth muscles other than those of the vascular system and the effects of sympathomimetic amines and adrenergic blocking agents on metabolism. The book also touches on veratrum alkaloids and neurotoxins, as well as botulism, tetanus, therapeutic use, and chemistry of veratrum alkaloids. The selection is a dependable reference for readers interested in the effects of drugs on the nervous system.

The Hallucinogens

  • 1st Edition
  • January 1, 1967
  • A. Hoffer + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 6 1 6 9 - 0
The Hallucinogens attempts to provide a detailed description of the hallucinogens in a single volume. Hallucinogens are chemicals which in nontoxic doses produce changes in perception, in thought, and in mood, but which seldom produce mental confusion, memory loss, or disorientation for person, place, and time. These latter changes are characteristic of organic brain reactions following intoxications with alcohol, anesthetics, and other toxic drugs. The book covers the following hallucinogens: plant ß-phenethylamines, d-lysergic acid diethylamide, ololiuqui, indole hallucinogens derived from tryptophan, and taraxein. The discussions include their chemistry, biochemistry, and neurophysiological effects. The final chapter deals with animal studies with hallucinogenic drugs. This work has been written for chemists, biochemists, psychologists, sociologists, and research physicians. While it cannot satisfy each group fully, it is sufficiently comprehensive and well documented so that each group can use it as a springboard for future enquiry into these fascinating chemicals.

Pharmacology of the Coronary Circulation

  • 1st Edition
  • January 1, 1965
  • Natalia V. Kaverina
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 5 3 5 - 4
Pharmacology of the Coronary Circulation focuses on the effects of pharmacological substances on the circulation of the heart, physiology of coronary circulation, effects of adrenomimetic, cholinergic, and ganglion-blocking agents, phenothiazine derivatives, analgesics, nitrites, and nitrates on cardiac vessels and results of clinical trials on Chloracizine. The publication first offers information on the physiology of the coronary circulation and the effects of pharmacological substances on the coronary circulation, including myotropic and neutropic substances and other substances. The book then examines the effects of adrenomimetic substances and cholinergic substances on the coronary circulation. The manuscript evaluates the effects of ganglion-blocking substances and analgesic substances on the coronary circulation. Topics include nicotine, etraethylammonium, hexamethonium, pentamine, and mecamine. The publication then takes a look at the effects of phenothiazine derivatives on the coronary circulation; importance of reflex reactions in connection with the development of acute coronary insufficiency; and effects of pharmacological substances on reflex reactions in the coronary vessels. The book is a dependable reference for readers interested in the pharmacology of the coronary circulation.

Pharmacology of Cholinergic and Adrenergic Transmission

  • 1st Edition
  • January 1, 1965
  • G. B. Koelle + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 5 3 9 - 2
Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 3: Pharmacology of Cholinergic and Adrenergic Transmission focuses on the effects of drugs on muscles, nerve fibers, and the central nervous system. The selection first offers information on the role of sodium ions in the release of acetylcholine and the distribution and release of acetylcholine in muscles. Discussions focus on the effects of sodium deficiency on ACh release in perfused ganglia; effects of sodium pump inhibitors on ganglionic and myoneural transmission; distribution of ACh and choline acetylase in muscle; and ACh release after denervation. The text then ponders on the roles of acetylcholine and acetylcholinesterase in junctional transmission and correlated studies of monoamines and acetylcholinesterase in sympathetic ganglia, manifesting the distribution of adrenergic and cholinergic neurons. The publication examines the action of acetylcholine and related drugs on mammalian nonmyelinated nerve fibers; possible mechanisms of acetylcholine action in muscles; and electrophysiological analysis of cholinergic transmission in sympathetic ganglia. The text then reviews the interactions of cholinomimetic and cholinergic blocking drugs at sympathetic ganglia; evolution of cholinoreceptive sites of locomotor muscle; and pharmacological blocking of central cholinoreactive systems and the possibilities of its therapeutic application. The selection is a dependable source of data for readers interested in the pharmacology of cholinergic and adrenergic transmission.