Books in Pharmacology

31-40 of 814 results in All results

Polymer-Drug Conjugates

1st Edition
July 5, 2023
Jitender Madan + 3 more
English
Paperback
9 7 8 - 0 - 3 2 3 - 9 1 6 6 3 - 9
eBook
9 7 8 - 0 - 3 2 3 - 9 1 6 9 0 - 5

Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of ‘Linker Chemistry’ in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.

Pharmacogenomics

1st Edition
June 13, 2023
Showkat Ahmad Ganie + 3 more
English
Paperback
9 7 8 - 0 - 4 4 3 - 1 5 3 3 6 - 5
eBook
9 7 8 - 0 - 4 4 3 - 1 5 3 3 7 - 2

Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The book's chapters over the foundational aspects of pharmacogenomics, including drug metabolism, drug discovery, development, and testing, and then detail studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. This is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. However, researchers and graduate students in the related fields of genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit from the structured approach of the book.

Bioactive Lipid Mediators in Cardiopulmonary Pharmacology

1st Edition
Volume 97
May 24, 2023
Darryl C Zeldin + 1 more
English
Hardback
9 7 8 - 0 - 3 2 3 - 9 5 0 5 7 - 2
eBook
9 7 8 - 0 - 3 2 3 - 9 5 0 5 8 - 9

Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast array of signaling pathways that regulate both physiological and pathophysiological responses. Chapters in this new release include Cyclooxygenases and Vascular Function, Cyclooxygenases and Platelet Function, Eicosanoids and Cardiomyopathies, Cytochrome P450 Bioactive Lipids in the Heart, Epoxide Hydrolase and Leukotoxin in the Heart and Lung, Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response, Bioactive Lipids in Hypertension, Cytochrome P450 Metabolites and Angiogenesis, 20-Hydroxyeicosatetraenoic Acid and Vascular Function, and more. Other critical sections cover Cytochrome P450 Eicosanoids and the Brain, Omega-3 Oxylipids, Resolvins, Lipoxins and Inflammation, Endocannabinoids as Bioactive Metabolites, and Oxylipins and Aspirin Exacerbated Respiratory Disease.

Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development

1st Edition
May 23, 2023
Kunal Roy
English
Paperback
9 7 8 - 0 - 4 4 3 - 1 8 6 3 8 - 7
eBook
9 7 8 - 0 - 4 4 3 - 1 8 6 3 9 - 4

Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development aims at showcasing different structure-based, ligand-based, and machine learning tools currently used in drug design. It also highlights special topics of computational drug design together with the available tools and databases. The integrated presentation of chemometrics, cheminformatics, and machine learning methods under is one of the strengths of the book.The first part of the content is devoted to establishing the foundations of the area. Here recent trends in computational modeling of drugs are presented. Other topics present in this part include QSAR in medicinal chemistry, structure-based methods, chemoinformatics and chemometric approaches, and machine learning methods in drug design. The second part focuses on methods and case studies including molecular descriptors, molecular similarity, structure-based based screening, homology modeling in protein structure predictions, molecular docking, stability of drug receptor interactions, deep learning and support vector machine in drug design. The third part of the book is dedicated to special topics, including dedicated chapters on topics ranging from de design of green pharmaceuticals to computational toxicology. The final part is dedicated to present the available tools and databases, including QSAR databases, free tools and databases in ligand and structure-based drug design, and machine learning resources for drug design. The final chapters discuss different web servers used for identification of various drug candidates.

Formulation of Monoclonal Antibody Therapies

1st Edition
May 20, 2023
Amal Ali Elkordy
English
Paperback
9 7 8 - 0 - 1 2 - 8 2 3 3 6 5 - 8
eBook
9 7 8 - 0 - 1 2 - 8 2 3 4 2 8 - 0

Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information on monoclonal antibodies, the book then discusses the importance of biopharmaceutical products, monoclonal antibodies, and biosimilars in treatment of chronic diseases, pharmaceutical aspects of mAbs, and how it can be administered. It also covers the industrial point of view and the clinical application of mAbs including in oncology, general medicine, rheumatology, hematology, dermatology, gastrointestinal tract, metabolic diseases, and dentistry. Formulation of Monoclonal Antibody Therapies: From Lab to Market is essential reading for researchers in biotechnology and biopharmaceutical fields, academics and pharmaceutical industrial scientists, and university students in pharmaceutical and biopharmaceutical sciences.

Anesthesia and Analgesia in Laboratory Animals

3rd Edition
May 17, 2023
Melissa Dyson + 4 more
English
Hardback
9 7 8 - 0 - 1 2 - 8 2 2 2 1 5 - 7
eBook
9 7 8 - 0 - 1 2 - 8 2 2 2 2 0 - 1

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. This will be a complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.

Neuropsychopharmacology

1st Edition
May 10, 2023
Jahangir Moini + 2 more
English
Paperback
9 7 8 - 0 - 3 2 3 - 9 5 9 7 4 - 2
eBook
9 7 8 - 0 - 3 2 3 - 9 5 9 7 3 - 5

Neuropsychopharmacology reviews the principles of pharmacology with a focus on the central nervous system and autonomic nervous system. Beyond autonomic and central nervous system pharmacology, this volume uniquely discusses psychiatric disorders and the pharmacological interventions that are available for conditions including depression, schizophrenia and anxiety disorders. With a focus on these specific body systems, readers will see end-of-chapter questions that offer real-world case studies, as well as multiple-choice questions for further learning. Beneficial features and content also include two extensive examination tests, which each contain 100 questions for better learning or to be used in teaching, and a glossary. Helpful appendices cover high-alert medications and toxicology effects on the nervous system. Each chapter will contain classifications of medications, pharmacokinetics, mechanism of action, clinical indications and toxicities.

Medicinal Chemistry of Anticancer Drugs

3rd Edition
April 28, 2023
Carmen Avendaño + 1 more
English
Paperback
9 7 8 - 0 - 1 2 - 8 1 8 5 4 9 - 0
eBook
9 7 8 - 0 - 1 2 - 8 1 9 6 5 2 - 6

This third edition of Medicinal Chemistry of Anticancer Drugs, provides an updated resource for students and researchers from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. This new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theranostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point of view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references to reviews and the primary literature.

Pharmaceutical Biotechnology in Drug Development

1st Edition
April 21, 2023
Muhammad Sajid Hamid Akash + 3 more
English
Paperback
9 7 8 - 0 - 4 4 3 - 1 9 1 3 5 - 0
eBook
9 7 8 - 0 - 4 4 3 - 1 9 1 3 6 - 7

Pharmaceutical Biotechnology in Drug Development summarizes key concepts and the latest developments of biotechnology applied to the development of biopharmaceuticals. Chapters present a comprehensive collection of introductory biotechnology technologies and their modern concepts and cover pharmacokinetic and pharmacodynamic behavior of biopharmaceuticals and modification techniques of amino acids and nucleic acid. Other sections focus on topics such as gene therapy, immunological preparations and nanoparticles which are the major contributions of pharmaceutical biotechnology. Final chapters discuss emerging techniques in the field of pharmaceutical biotechnology to meet current patient and health care demand. This book is an essential reference useful for pharmaceutical scientists, clinicians and academic researchers who want easy access to up-to-date practices of pharmaceutical biotechnology. Corporate researchers will also benefit from this book’s succinct and objective content structure.

Rang & Dale's Pharmacology

10th Edition
April 17, 2023
James M. Ritter + 6 more
English
Paperback
9 7 8 - 0 - 3 2 3 - 8 7 3 9 5 - 6
eBook
9 7 8 - 0 - 3 2 3 - 8 7 3 9 8 - 7

Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing.