Cell Chemical Biology

Cell Chemical Biology is a Cell Press journal that aims to publish the most important advances in chemical biology research of exceptional interest for our diverse community, from basic scientists to clinicians. Launched in 1994 under the title Chemistry & Biology, the journal was the first to recognize the growing importance of investigations at the interface of chemistry and biology. The mission has always been to support and promote chemical biology and conversation and collaboration between chemical and life sciences. Cell Chemical Biology strongly encourages submission of articles that provide significant conceptual advancement of broad general interest to researchers within chemical, biological, clinical, and associated fields. We are especially interested in papers that combine the use of chemical tools to perturb, visualize, and measure biological systems and cellular processes and offer unique insights into molecular mechanisms or disease biology, and therapeutics.

We welcome submissions that are focused on method development highlighting significant technical advancements in chemical probes, tools, and technologies, including imaging tools, analytical platform development and application strategies for basic life sciences or that have practical impact for either drug development, or clinical and biotechnological advances.

Research areas that we consider within our scope include but are not limited to studies of biochemistry, metabolism, and physiology; drug discovery; cancer biology; immunology, immunomodulation; neuromodulation; transcription/gene regulation; disease mechanism and therapeutics; new therapeutic modalities; signaling pathways; virology; molecular microbiology; natural product biosynthesis; generation, distribution, and function of small molecule-protein conjugates such as post-translational modifications; mechanism of resistance to small molecules by viruses/bacteria/cancer cells/organisms; intra- and intercellular and intra- and interspecies communication mediated by small molecules; and chemical biology of lipids, sugars, and nucleic acids.

Finally, large-scale studies enabled by the use of chemistry-based technology, such as proteomics, lipidomics, metabolomics, transcriptomics, genomics, and glycomics, are also within our scope, as well as synthetic and systems biology work when inspired and supported by chemical tools or aimed at engineering biological systems to perform a new type of chemical transformation.

Cell Chemical Biology mission statement

We publish, support, and promote chemical biology, a unique discipline that harnesses power of chemistry to deliver profound insights into biological function, and develop solutions for life sciences, biotechnology, and human health. Our mission is to publish review and research content that pushes biology and our ability to study it forward and to have an editorial reputation for integrity, responsiveness, fairness, and friendliness.

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