Elsevier’s Oncology Journal Network highlights

Explore the latest breakthroughs shaping cancer research and clinical care with Elsevier’s Oncology Journal Network highlights. Bringing together insights from leading peer-reviewed oncology journals, this collection showcases cutting-edge studies, emerging therapies, and expert perspectives across the cancer continuum—from prevention and diagnosis to treatment and survivorship. Designed for researchers, clinicians, and healthcare professionals, it offers a curated view of high-impact oncology research driving innovation and improving patient outcomes worldwide.

Melanoma Awareness Month

• Carbon-Ion Radiotherapy for Head and Neck Mucosal Melanoma: Preliminary Clinical Outcomes and the MedAustron Approach for Reporting RBE-Weighted Dose With 2 Models

• PTCOG Ocular Survey – Perspective on Ocular Particle Therapy: Current Practices and Emerging Trends

• Immunotherapy for anorectal melanoma: A case report - ScienceDirect

• Cutaneous toxicity following intra-arterial chemotherapy with melphalan for uveal melanoma: A case report

• Unusual presentation and course of malignant melanoma of anal canal in an African-American patient

• S-adenosylmethionine blocks tumorigenesis and with immune checkpoint inhibitor enhances anti-cancer efficacy against BRAF mutant and wildtype melanomas

• Tozasertib activates anti-tumor immunity through decreasing regulatory T cells in melanoma

• Acral melanoma: new insights into the immune and genomic landscape - ScienceDirect

• Anti-PD-1/PD-L1 therapy for colorectal cancer: Clinical implications and future considerations

• Corresponding ctDNA and tumor burden dynamics in metastatic melanoma patients on systemic treatment

• Peroxisome proliferator-activated receptors: Key regulators of tumor progression and growth

• The role of coenzyme Q10 as a preventive and therapeutic agent for the treatment of cancers

• Gamma Knife Stereotactic Radiosurgery With a Reduced Peripheral Dose: Outcomes in Uveal Melanoma Patients

• New Findings in the Visualization of Subepithelial Melanoma or Pseudoprogression-Like Phenomena in Oral Mucosal Melanoma During Carbon-Ion Radiation Therapy

• Carbon Ion Versus Photon-based Stereotactic Ablative Radiation Therapy for Patients with Choroidal Melanoma

• Surgical Reconstruction Toxicity Following Hypofractionated Adjuvant Radiation Therapy for Primary Cutaneous Melanoma

• Staged I-125 Eye Plaque Brachytherapy for the Treatment of Large Uveal Melanoma: A Single Institution Experience

• Stereotactic Radiation Therapy or Protons for Uveal Melanoma Patients? An Artificial Intelligence (AI)-Based Clinical Treatment Decision-Making Tool Predicting Doses To Radiation Therapy Constraints

• Synchrotron Microbeam Radiation Therapy in Combination With Gold Nanoparticles Improves Control of Mouse Melanoma

• Tirbanibulin 1 % ointment: A narrative review of new data presented at the 11th World Congress of Melanoma in conjunction with 21st European Association of Dermato-Oncology Congress 2025

• BRAF/MEK inhibitor rechallenge in patients with non-resectable or metastatic BRAF V600-mutated melanoma: A stratified, controlled, retrospective EUMelaReg multicenter study

• CLAUDIUS Study: Risk of materno-fetal transmission of melanoma cells in pregnant women with high grade melanoma – A retrospective multicenter study and literature review

• Comparative analysis of progression free survival and treatment maintenance in patients with advanced melanoma responding to first-line treatment

• Mutational landscape of oral mucosal melanoma based on comprehensive cancer genomic profiling tests in a Japanese cohort

• Twelve years after: The french national network on rare head and neck tumours (REFCOR)

• Immuno-oncology approaches to overcome T cell exhaustion in melanoma

• Deciphering the prognostic value and immunotherapeutic strategy of aggrephagy in melanoma: Integrating single-cell sequencing and machine learning

• Role of neoadjuvant pembrolizumab in advanced melanoma

• Metabolism at the core of melanoma: From bioenergetics to immune escape and beyond

• Sapogenin-based nanoscale assemblies induce immunogenic cell death, remodel the tumor microenvironment, and drive systemic antitumor immunity in melanoma

• Irreversible electroporation activates the NLRP3 inflammasome pathway mediating the antitumor immune responses in pancreatic cancer

• Cancer overdiagnosis: A challenge in the era of screening

• Chromatin assembly factor 1 suppresses epigenetic reprogramming toward adaptive drug resistance

• Overview of skin cancer types and prevalence rates across continents

• Survival benefits and toxicity effects of radiotherapy and immunotherapy treatments in melanoma patients with brain metastases: A meta-analysis

• State-of-the-art machine learning techniques for melanoma skin cancer detection and classification: a comprehensive review

Lung Cancer article collection

Cancer Letters

• Autophagy-driven regulation of cisplatin response in human cancers: Exploring molecular and cell death dynamics

• Reprogramming of TAMs via the STAT3/CD47-SIRPα axis promotes acquired resistance to EGFR-TKIs in lung cancer

• The interplay between autophagy and apoptosis: its implication in lung cancer and therapeutics

Cancer Pathogenesis and Therapy

• Epithelial–mesenchymal transition (EMT) and its role in acquired epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) chemoresistance in non-small cell lung cancer (NSCLC)

• Inflammatory cytokines and specific factors influencing lung cancer progression

• Targeting tumor-associated neutrophils: A promising strategy in lung cancer immunotherapy

• Amide proton transfer-weighted MRI in predicting pathological types of brain metastases in lung Cancer

Cancer Treatment and Research Communications

• Time from immune checkpoint inhibitor to sotorasib use correlates with risk of hepatotoxicity in non-small cell lung cancer: A brief report

• The prognostic impact of KRAS, TP53, STK11 and KEAP1 mutations and their influence on the NLR in NSCLC patients treated with immunotherapy

• Personalized medicine: An alternative for cancer treatment

Chinese Medical Journal Pulmonary and Critical Care Medicine

• Mechanisms and current advances in treating KRAS-mutated lung cancer

• Temporal trends in the burden of tracheal, bronchial, and lung cancer in China and globally: A comprehensive analysis from 1990 to 2021

• Sphingolipid metabolism dysregulation: A cause for lung cancer development, progression, and resistance to therapies

• Heterogeneity and therapeutic implications of cancer-associated fibroblasts in lung cancer: Recent advances and future perspectives

Clinical Lung Cancer

• TARGET: A Phase II, Open-Label, Single-Arm Study of 5-Year Adjuvant Osimertinib in Completely Resected EGFR-Mutated Stage II to IIIB NSCLC Post Complete Surgical Resection

• Lung Cancer in Women: The Past, Present, and Future

• Pembrolizumab Plus Chemotherapy Per PD-L1 Stratum In Patients With Metastatic Non–Small Cell Lung Cancer: Real-World Effectiveness Versus Trial Efficacy

• Amivantamab, an Epidermal Growth Factor Receptor (EGFR) and Mesenchymal-epithelial Transition Factor (MET) Bispecific Antibody, Designed to Enable Multiple Mechanisms of Action and Broad Clinical Applications

• Young Onset Lung Cancer in India: Insights Into Clinical, Demographic, and Genomic Profiles

Current Problems in Cancer: Case Reports

• Use of anamorelin hydrochloride in a patient with lung cancer-related cachexia undergoing chemoradiotherapy: A case report

• High-flow nasal cannula combined with intravenous general anesthesia for stent implantation in right lung cancer: A case report

• Rare case of de novo EGFR L718V mutation-positive non-small cell lung cancer successfully treated with afatinib

International Journal of Particle Therapy

• NTCP-Based Prediction of Lung Sparing With IMPT in BC Patients and Implication of Patient Selection

• Comprehensive Robustness Evaluation of Proton and Carbon-Ion Plans in Thoracic Cancer Treatment

• Definitive Proton Beam Therapy for Second Primary Non–small Cell Lung Cancer After Pneumonectomy

• Feasibility of Utilizing Spot-Scanning Proton Arc (SPArc) for Whole-Lung Irradiation: A Case Report

Journal of the National Cancer Center

• Cancer incidence and mortality in China, 2022

• Immunological features of EGFR-mutant non-small cell lung cancer and clinical practice: a narrative review

• Long-term exposure to ozone and incidence of lung cancer in China: data based on a national population cohort (ChinaHEART)

Journal of Thoracic Oncology

• Lung Cancer in Jordan

• Lung Cancer in Norway

• Lung Cancer in Tanzania

• Lung Cancer in Argentina

• Advances in Lung Cancer Basic and Translational Research in 2025 – Overview and Perspectives Focusing on NSCLC

• 50 Years of Progress in NSCLC: A New Fellow’s Guide in the Clinic

• Safety and Sample Adequacy for Comprehensive Biomarker Testing of Bronchoscopic Biopsies: An American Association of Bronchology and Interventional Pulmonology and International Association for the Study of Lung Cancer Clinical Practice Guideline

• Screening for Lung Cancer, Overdiagnosis, and Healthcare Utilization: A Nationwide Population-Based Study

• Risk-Based Lung Cancer Screening in Clinical Practice

• Prospective Evaluation of Lung Cancer Screening Eligibility Criteria and Lung Cancer Detection in the Yorkshire Lung Screening Trial

• Screening-Detected Versus Interval Lung Cancer in the Biennial Korean National Lung Cancer Screening Program: Proportion, Characteristics, and Mortality

• Barriers to Lung Cancer Screening in a Multi-Disciplinary Thoracic Oncology Program Cohort: Effects of an Incidental Pulmonary Nodule Program

• Molecular Tumor Boards: A Consensus Statement From the International Association for the Study of Lung Cancer

• Low Dose Computed Tomography for Lung Cancer Screening in Tuberculosis Endemic Countries: A Systematic Review and Meta-Analysis

• Lung Cancer Screening Program Quality Indicators—Review and Recommendations: An International Association for the Study of Lung Cancer Delphi Process Study

• Impact of Comorbidities on the Mortality Benefits of Lung Cancer Screening: A Post-Hoc Analysis of the PLCO and NLST Trials

• Predicted Effect of Incidental Pulmonary Nodule Findings on NSCLC Mortality

• Overdiagnosis of Lung Cancer Due to the Introduction of Low-Dose Computed Tomography in Average-Risk Populations in the People’s Republic of China

• Recommendations for Standardization of Tobacco Use Treatment Data

• The Use of Investigator-Assigned Subjective or Judgmental Efficacy and Toxicity Reporting in Early Phase Clinical Trials of Lung Cancer Treatments

• The International Association for the Study of Lung Cancer Staging Project: The Impact of Smoking Status on Lung Cancer Staging in the Ninth Edition of the TNM Classification

• The Risk and Reversibility of Osimertinib-Related Cardiotoxicity in a Real-World Population

• The 2024 International Association for the Study of Lung Cancer Global Survey on Biomarker Testing

• Current and Future Perspectives on Computed Tomography Screening for Lung Cancer: A Roadmap From 2023 to 2027 From the International Association for the Study of Lung Cancer

• Second Primary Lung Cancer – An Emerging Issue in Lung Cancer Survivors

• Lung Cancer Oncogene-Directed Therapy, Fertility, and Pregnancy

• Neoadjuvant and Adjuvant Treatments for Early Stage Resectable NSCLC: Consensus Recommendations From the International Association for the Study of Lung Cancer

• American Radium Society Appropriate Use Criteria on Cardiac Toxicity Prevention and Management After Thoracic Radiotherapy

Lung Cancer

• Advanced-stage ALK-positive non–small-cell lung cancer (NSCLC) patients: Real-world treatment patterns and outcomes from the Italian biomarker ATLAS database

• An international and multidisciplinary EORTC survey on resectability of stage III non-small cell lung cancer

• Definition of resectable stage III non-small cell lung cancer: A systematic review from EORTC lung cancer group

Neoplasia

• Lung cancer lesion detection in histopathology images using graph‐based sparse PCA network

• Evidence based on Mendelian randomization: Causal relationship between mitochondrial biological function and lung cancer and its subtypes

• Dihydroartemisinin, a potential PTGS1 inhibitor, potentiated cisplatin-induced cell death in non-small cell lung cancer through activating ROS-mediated multiple signaling pathways

Radiation Medicine and Protection

• A meta-analysis of the diverse invasion and migration responses of lung cancer cells to photon irradiation

• A summary of UNSCEAR 2019 report on lung cancer from exposure to radon and research needs

• Regulator of G protein signaling 20 contributes to radioresistance of non-small cell lung cancer cells by suppressing pyroptosis

Seminars in Oncology

• Explainable machine learning and feature interpretation to predict survival outcomes in the treatment of lung cancer

• Chemotherapy plus immunotherapy as first line combination in older patients with extensive stage small cell lung cancer: A systematic review and meta-analysis

Seminars in Ultrasound, CT and MRI

• The Role of Chest Radiography in Lung Cancer

• Imaging of Lung Cancer Staging: TNM 9 Updates

Translational Oncology

• Systemic immune-inflammation index predicts survival in patients with resected lung invasive mucinous adenocarcinoma

• Tumor mutation burden in the prognosis and response of lung cancer patients to immune-checkpoint inhibition therapies

• Anti-PD-1/PD-L1 therapy for colorectal cancer: Clinical implications and future considerations

Elsevier’s Oncology Journal Network