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using Reaxys can help you design safe and effective compounds?
Plan your structure-activity-relationship (SAR) studies and assess the potential for off-target interactions with comprehensive access to extracted substances, targets and bioactivity data, from journals and patents.
Reaxys extracts substances, target, and bioactivity data from key patent offices, including those in Asia (CN, KR, JP, and TW), with titles, abstracts, and claims fully translated into English for instant accessibility. This provides researchers with a competitive edge in the drug discovery process, helping them gain a more complete understanding of global trends, emerging compounds, and potential therapeutic applications.
Reaxys' bioactivity visualization feature empowers you to:
Easily view structures alongside their bioactivity values across various targets
Compare data points effortlessly with normalized pX values
With the world’s largest database of targets, bioactivity, and toxicology data, Reaxys enables you to pinpoint SAR, ADME data, and toxicity values, helping you optimize leads and evaluate substance-target interactions with confidence.
Reaxys offers dedicated forms in the Query Builder to streamline your workflow and simplify complex searches. These forms are tailored to key topics such as Affinity on Target, Selectivity Profiles, Animal Models, and more, helping you achieve precise results faster and more efficiently.
Reaxys allows you to directly search and access in-vivo bioactivity data for specific species or animal models. This data enhances the development of structure-activity relationship (SAR) and ADME/Tox models, enabling more accurate predictions of human outcomes and supporting a more efficient drug discovery process.
In Reaxys, you can access all bioactivity data reported for a substance, easily assessing all targets for which it has reported activity, including on-target and off-target effects.
Reaxys includes 47 million bioactivity data points from patents and journals, allowing you to search and access detailed information on pharmacokinetic properties, affinity, potency, specificity, toxicity, and off-target activity of all compounds published in a patent. This is invaluable for target identification and validation, as well as optimizing drug profiles.
With Reaxys, you can easily export bioactivity data from the bioactivity visualization table for SAR analysis. This export provides detailed, high-quality data in a user-friendly format, facilitating offline analysis and seamless integration with widely used SAR tools.
Start a conversation with your local expert
Erik Siemens, Regional Director, Chemistry Contact Erik to get in touch opens in new tab/windowwith his team of chemistry experts covering Europe, Middle East and Africa
Randy Kenien, Regional Director, Chemistry Contact Randy to get in touch opens in new tab/windowwith his team of chemistry experts covering USA, Canada, Central and South America
Eric Tan, Regional Director, Chemistry Contact Eric to get in touch opens in new tab/windowwith his team of chemistry experts covering Japan, China, Korea, Singapore, Taiwan, Australia and New Zealand
