Ventilation, Blood Flow, and Diffusion - 1st Edition - ISBN: 9780127445014, 9780323154550

Ventilation, Blood Flow, and Diffusion

1st Edition

Editors: John West
eBook ISBN: 9780323154550
Imprint: Academic Press
Published Date: 28th January 1980
Page Count: 354
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Pulmonary Gas Exchange, Volume I: Ventilation, Blood Flow, and Diffusion considers the mechanisms of gas exchange in the lung. This volume is composed of nine chapters that particularly discuss the roles of ventilation, blood flow, and diffusion in pulmonary gas exchange. The opening chapter briefly traces the history of the chemistry and physics of pulmonary gas exchange. The next two chapters are devoted to the momentous developments that took place near the end of the Second World War advances which established the modern basis of gas. The remaining chapters describe the mechanism of gas exchange in the alveoli, how it crosses the blood-gas barrier, and the way in which ventilation-perfusion relationships determine the efficiency of exchange. This book will be of great benefit to pulmonologists and researchers in the biomedical field.

Table of Contents

List of Contributors Preface Contents of Volume II 1 Historical Development I. Introduction II. Knowledge prior to the Seventeenth Century III. Seventeenth and Eighteenth Centuries IV. Nineteenth Century V. Alveolar Gas and Dead Space VI. Secretion versus Diffusion VII. Blood Gases References 2 Development of Concepts in Rochester, New York, in the 1940s I. Introduction II. Equipment III. The High-Altitude Chamber IV. Sampling and Analysis of Alveolar Gas V. The Oxygen-Carbon Dioxide Diagram VI. The Ventilation-Perfusion Relationship VII. The Pressure-Volume Diagram IX. Retrospect Appendix References 3 Development of the Three-Compartment Model for Dealing with Uneven Distribution I. Cast of Characters during World War II II. Alveolar Gas and End-Capillary Blood III. The Three-Compartment Model IV. Reflections on a Simpler Era V. Newer Models for New Times References 4 Intrapulmonary Gas Mixing and Stratification I. Concepts and Significance II. Diffusion in Gas Phase III. Diffusion in Convective Flow IV. Anatomical Basis for Lung Models V. Mathematical Analysis of Gas Mixing in the Lung VI. Experimental Approaches to Identification of Stratified Inhomogeneity VII. Conclusions VIII. Appendix: Stratification in Nonmammalian Vertebrates References 5 Blood- Gas Equilibration in Lungs I. Equilibrium Condition II. Diffusion Limitation: Concept and General Model III. Lung Models and Experimental Designs for Determination of Pulmonary Diffusing Capacity IV. Problems in Application of Models to Real Lungs V. Gas-Blood Equilibration in Functionally Inhomogeneous Lungs VI. Pulmonary Diffusing Capacity References 6 Kinetics of Pulmonary Gas Exchange I. Experimental Techniques II. O


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© Academic Press 1980
Academic Press
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About the Editor

John West

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