Vaccines for Biodefense and Emerging and Neglected Diseases
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The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease.
Key Features
* Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats
* Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace
* Each chapter will include a map of the world showing where that particular disease is naturally found
* Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace
* Each chapter will include a map of the world showing where that particular disease is naturally found
Readership
Primary: Researchers and physicians in vaccinology, virology, microbiology, parasitology and infectious diseases. Secondary: public health officials.
Table of Contents
- Agents of Emerging Infectious Diseases; Bacterial biothreats agents; Viral Biothreat agents; Vaccine Development Pathway; Immunology of Vaccines; Molecular Approches to Bacterial Vaccines; Viral Vectors; DNA Vaccines; Vaccine Adjuvants; Preclinical Vaccine Development; Vaccine Manufacturing; Clinical Trials of Vaccines; Pre-IND/IND Process; Regulatory Issues-USA; Special Issues around Veterinary Vaccines; Vaccines Misinformation; Vaccine for Military Application; Dengue; Filoviruses; Alphaviral Encephalitides; Foot & Mouth; Hantaviruses;
Hepatitis; HIV; Human papillomavirus; Influenza; Japanese encephalitis; Junin & other Arenaviruses; Measles; Nipah and Hendra; O'Nyong, N'yong, and Chikungunya Viruses; Rabies; Ross River Virus; Rotavirus; SARS; Smallpox; Tick Borne Encephalitis; West Nile Virus; Yellow Fever; Anthrax; Brucellosis; Burkholderia mallei and Burkholderia pseudomallei; Chlamydia; Cholea; Botulinum; Erlichia; Extraintestinal pathogenic E. coli; Gonnorhea; Helicobactor pylori; Intestinal pathogenic E. coli; Lyme Disease; Niesseria meningitidis; Plague; Ricin-a toxin; Rickettsia; Salmonella; Shigella; Syphilis; Tuberculosis; Tularemia; African trypanosomiasis; Leishmaniasis; Leptospirosis; Malaria; Hookworm; Onchocerciasis; Schistosomiasis; American Trypanosomiasis
Product details
- No. of pages: 1488
- Language: English
- Copyright: © Academic Press 2008
- Published: December 17, 2008
- Imprint: Academic Press
- eBook ISBN: 9780080919027
About the Authors
Alan D.T. Barrett
Drs. Stanberry and Barrett are highly respected authorities in vaccine development. Dr. Barrett researches tropical virus diseases such as dengue, West Nile, yellow fever and Japanese encephalitis. He has made important contributions to molecular aspects of immunogens and preclinical development of candidate vaccines for these diseases, and studies on the current yellow fever 17D vaccine. Dr Stanberry focuses on sexually transmitted diseases research and has made important contributions in the area of tropical microbicides an in herpes simplex virus pathogenesis, immunobiology, and antiviral therapy. He has played major roles in the pre-clinical and clinical assessment of many of the herpes vaccines currently in development.
Affiliations and Expertise
Sealy Center for Vaccine Development, University of Texas at Galveston, USA
Lawrence Stanberry
Dr. Stanberry is a highly respected authority in vaccine development. Dr. Stanberry focuses on sexually transmitted diseases research and has made important contributions in the area of tropical microbicides an in herpes simplex virus pathogenesis, immunobiology, and antiviral therapy. He has played major roles in the pre-clinical and clinical assessment of many of the herpes vaccines currently in development.
Affiliations and Expertise
College of Physicians and Surgeons, Columbia University, New York, USA
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