Ulcerative Colitis, An Issue of Gastroenterology Clinics of North America

1st Edition, Volume 49-4 - November 11, 2020
Editor: Scott Lee
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 3 5 5 8 - 9
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 3 5 5 9 - 6

Together with Consulting Editor, Dr. Alan Buchman, Dr. Scott Lee has put together a state-of-the-art issue of Gastroenterology Clinics devoted to Ulcerative Colitis (UC). He has… Read more

Ulcerative Colitis, An Issue of Gastroenterology Clinics of North America

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Together with Consulting Editor, Dr. Alan Buchman, Dr. Scott Lee has put together a state-of-the-art issue of Gastroenterology Clinics devoted to Ulcerative Colitis (UC). He has selected expert authors to contribute clinical reviews that provide the latest clinical findings and recommendations. Articles are devoted to the following topics: Epidemiology and pathogenesis of UC; Making initial diagnosis of UC and ruling out other diseases that mimic UC; Assessing severity of disease; Initial medical treatment of UC; Treatment of UC with steroids; Biologic therapy in UC; Non-biologic immune suppression in UC; Microbiome and fecal transplant in UC; Health maintenance in UC, including bone density scan, vaccination recommendations, cancer screening; Women's issues and UC; Risk of colon cancer and recommended surveillance strategies in UC patients; Surgical management of UC, indications and outcomes from colectomy; and Management of J-pouches. Readers will come away with the latest clinical recommendations they need to improve outcomes in patients with UC.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Epidemiology and Pathogenesis of Ulcerative Colitis
Key points
Introduction
Epidemiology
Pathophysiology
Genetics
Diet
Microbiome
Smoking
Appendectomy
Living conditions and hygiene
Medications
Summary
Ulcerative Colitis: Making the Diagnosis
Key points
Introduction
Clinical presentation
Differential diagnosis
Physical examination
Laboratory workup
Imaging
Endoscopic evaluation
Microscopic evaluation
Atypical features
Disease classification
Summary
Assessing Severity of Disease in Patients with Ulcerative Colitis
Key points
Introduction
Summary
Clinical care points
Mesalamine in the Initial Therapy of Ulcerative Colitis
Key points
Introduction
Evolution of mesalamine in ulcerative colitis therapy
Mesalamine formulations
Summary
Treatment of Ulcerative Colitis with Steroids (in Whom, How Long, What Dose, What Form)
Key points
Introduction
History
Background
Discussion
Summary
Clinical care points
Biologic Therapy for Ulcerative Colitis
Key points
Introduction
Summary
Nonbiologic Immune Suppression in Ulcerative Colitis
Key points
Introduction
Efficacy of nonbiologic immunosuppressive therapies in ulcerative colitis
Safety and monitoring of nonbiologic immunosuppressive therapies in ulcerative colitis
Summary
Fecal Microbiota Transplantation for Ulcerative Colitis. Are We Ready for Primetime?
Key points
Introduction
Discussion
Summary
Surgical Management of Ulcerative Colitis
Key points
Introduction
History
Definitions
Discussion/surgical options for ulcerative colitis
Summary
Clinics care points
Women’s Health and Ulcerative Colitis
Key points
Introduction
Menstrual cycle and menopause
Fertility and fecundity
Pregnancy
Management of disease flares
Health maintenance recommendations for females with ulcerative colitis
Summary
Key points in clinical care
Risk of Colon Cancer and Recommended Surveillance Strategies in Patients with Ulcerative Colitis
Key points
Introduction
Epidemiology of colorectal cancer in inflammatory bowel disease
Risk factors for dysplasia and colorectal cancer in ulcerative colitis
Colorectal cancer prevention and mitigation
Colonoscopic prevention with screening and surveillance strategies
Practical approach and recommendations
Health Maintenance in Patients with Ulcerative Colitis
Key points
Introduction
Immunizations
Cancer screening/prevention
Bone health/fracture prevention
Micronutrient deficiencies
Mental health screening
Summary